DE923384C - Process for the production of elastic radioactive irradiation devices - Google Patents
Process for the production of elastic radioactive irradiation devicesInfo
- Publication number
- DE923384C DE923384C DEC7729A DEC0007729A DE923384C DE 923384 C DE923384 C DE 923384C DE C7729 A DEC7729 A DE C7729A DE C0007729 A DEC0007729 A DE C0007729A DE 923384 C DE923384 C DE 923384C
- Authority
- DE
- Germany
- Prior art keywords
- radioactive
- elastic
- production
- organosilicon compound
- irradiation devices
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
Description
Verfahren zur Herstellung elastischer radioaktiver Bestrahlungs einrichtungen Die Erfindung bezieht sich auf elastische, radioaktive Bestrahlungseinrichtungen, sogenannte Applikatoren, vorzugsweise in Form von Flächengebilden, Folien, aufblasbaren Hohlkörpern od. dgl., und Verfahren zu ihrer Herstellung.Process for the production of elastic radioactive irradiation devices the The invention relates to elastic, radioactive irradiation devices, so-called Applicators, preferably in the form of flat structures, foils, inflatable hollow bodies or the like, and processes for their preparation.
Es ist bekannt, radioaktive Strahler, etwa 32p, in Polyäthylenfolien einzuarbeiten und diese Flächenstrahler in der Therapie zu verwenden. It is known to use radioactive emitters, about 32p, in polyethylene sheeting incorporate and use these surface emitters in therapy.
Auch wurde bereits vorgeschlagen, radioaktive Strahler in Gummifolien einzubringen oder Gummifolien mit einer aktiven Schicht zu versehen, die ihrerseits wieder mit einer inaktiven Gummischicht überdeckt wird. Diese Strahler haben den Nachteil, daß sie zum Zweck der Sterilisierung nur relativ niedrig erhitzt werden können, da die Trägerfolie selbst sonst leidet. Sollen also solche Strahler aus elastischem Trägermaterial für therapeutische Zwecke Verwendung finden, so ist ihre Temperaturempfindlichkeit ein schwerwiegender Nachteil. Eine Hitzesterilisation, bei welcher sowohl Bakterien wie Sporen abgetötet werden, ist unmöglich. Nun gibt es zwar eine Reihe von elastischen Kunststoffen, die bessere Temperaturbeständigkeit haben als Naturkautschuk. Doch muß das Trägermaterial außer der Elastizität und Temperaturbeständigkeit auch noch die Bedingung erfüllen, daß es durch die radioaktive Strahlung nicht in Kürze zerstört wird. Naturgummi z. B. wird durch Betastrahlung relativ rasch mürbe gemacht und verliert so einmal seine Elastizität, zum anderen wird seine Zerreißfestigkeit durch Bestrahlung bald stark herabgesetzt.It has also already been proposed to use radioactive emitters in rubber sheets to bring in or to provide rubber sheets with an active layer, which in turn is covered again with an inactive rubber layer. These emitters have the Disadvantage that they are only heated relatively low for the purpose of sterilization otherwise the carrier film itself suffers. So should such emitters If elastic carrier material is used for therapeutic purposes, it is theirs Temperature sensitivity a serious disadvantage. A heat sterilization, in which both bacteria and spores are killed is impossible. Well there Although there are a number of elastic plastics that have better temperature resistance have as natural rubber. But the carrier material must besides the elasticity and Temperature resistance also meet the condition that it is radioactive Radiation will not be destroyed shortly. Natural rubber z. B. is caused by beta radiation worn down relatively quickly and thus loses its elasticity on the one hand, and on the other its tensile strength will soon be greatly reduced by irradiation.
Es wurde nun gefunden, daß sich eine Stoffgruppe vor anderen besonders auszeichnet, da sie I. bis zu Temperaturen über 2000 hitzebeständig, also auch sterilisierbar ist, ohne ihre elastischen und Festigkeitseigenschaften einzubüßen, 2. gegen radioaktive Strahlungen, insbesondere auch Betastrahlung, relativ unempfindlich ist und sich 3. mindestens ebenso leicht wie etwa Naturkautschuk verarbeiten und in beliebige Form bringen läßt. It has now been found that one group of substances stands out above others distinguishes itself because it is heat-resistant up to temperatures of over 2000, so it can also be sterilized is without its elastic and loss of strength properties, 2. Relatively insensitive to radioactive radiation, especially beta radiation is and 3. can be processed at least as easily as natural rubber and can be brought into any shape.
Es handelt sich hierbei um die polymeren Organosiliciumverbindungen. These are the polymeric organosilicon compounds.
Die Erfindung beruht auf der Erkenntnis der ausgezeichneten Eignung eines derartigen Werkstoffes für die Herstellung elastischer, radioaktiver Applikatoren. Als Strahler finden vorzugsweise nichtemanierende Stoffe Verwendung, z. B. Radiokobalt in Pulverform oder in Form seines Oxydes 60Co3 04. The invention is based on the knowledge of the excellent suitability such a material for the production of elastic, radioactive applicators. Non-remaning substances are preferably used as emitters, e.g. B. Radiocobalt in powder form or in the form of its oxide 60Co3 04.
Die Einbringung oder Aufbringung der Strahler in oder auf den erfindungsgemäß als Trägerfolie verwendeten Werkstoff kann auf beliebige zweckentsprechende Weise erfolgen. Beispielsweise können die radioaktiven Stoffe in Form von echten Lösungen oder auch von Suspensionen der monomerken oder wenigstens noch niedrigmolekularen Organosiliciumverbindung zugesetzt werden, die dann erst polymerisiert wird. Die den Strahler enthaltenden monomeren oder niedrigmolekularen Organosiliciumverbindungen können auch in Form einer Schicht auf einer bereits vorliegenden Folie des Polymers aufgetragen, auf dieser fertig polymerisiert und schließlich noch durch eine inaktive Schutzschicht des Polymers bedeckt werden. Die so hergestellten elastischen, radioaktiven Flächengebilde können z. B. auch in Form von' Hohlkörpern hergestellt werden, die sich in bekannter Weise vorzugsweise für die Bestrahlung von Körperhöhlen benutzen lassen. The introduction or application of the radiators in or on the according to the invention The material used as the carrier film can be used in any appropriate manner take place. For example, the radioactive substances can be in the form of real solutions or also from suspensions of the monomeric or at least still low molecular weight Organosilicon compound are added, which is then polymerized. the the emitter containing monomeric or low molecular weight organosilicon compounds can also be in the form of a layer on an already existing film of the polymer applied, polymerized on this and finally by an inactive one Protective layer of the polymer are covered. The elastic, radioactive ones produced in this way Flat structures can, for. B. are also produced in the form of 'hollow bodies, the use themselves in a known manner, preferably for the irradiation of body cavities permit.
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEC7729A DE923384C (en) | 1953-06-16 | 1953-06-16 | Process for the production of elastic radioactive irradiation devices |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEC7729A DE923384C (en) | 1953-06-16 | 1953-06-16 | Process for the production of elastic radioactive irradiation devices |
Publications (1)
Publication Number | Publication Date |
---|---|
DE923384C true DE923384C (en) | 1955-02-10 |
Family
ID=7014190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DEC7729A Expired DE923384C (en) | 1953-06-16 | 1953-06-16 | Process for the production of elastic radioactive irradiation devices |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE923384C (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1127598B (en) * | 1956-08-10 | 1962-04-12 | Cooke Troughton & Simms Ltd | Optical instrument |
DE1274277B (en) * | 1960-11-14 | 1968-08-01 | Dr Med Walter Jacoby | Carrier for drugs or therapeutically active substances |
-
1953
- 1953-06-16 DE DEC7729A patent/DE923384C/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1127598B (en) * | 1956-08-10 | 1962-04-12 | Cooke Troughton & Simms Ltd | Optical instrument |
DE1274277B (en) * | 1960-11-14 | 1968-08-01 | Dr Med Walter Jacoby | Carrier for drugs or therapeutically active substances |
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