DE722408C - Process for the production of a neutral complex thorium sodium tartrate - Google Patents

Process for the production of a neutral complex thorium sodium tartrate

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Publication number
DE722408C
DE722408C DEC55873D DEC0055873D DE722408C DE 722408 C DE722408 C DE 722408C DE C55873 D DEC55873 D DE C55873D DE C0055873 D DEC0055873 D DE C0055873D DE 722408 C DE722408 C DE 722408C
Authority
DE
Germany
Prior art keywords
thorium
production
sodium tartrate
tartrate
neutral complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEC55873D
Other languages
German (de)
Inventor
Dr Rudolf Gebauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemische Fabrik Von Heyden AG
Original Assignee
Chemische Fabrik Von Heyden AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemische Fabrik Von Heyden AG filed Critical Chemische Fabrik Von Heyden AG
Priority to DEC55873D priority Critical patent/DE722408C/en
Application granted granted Critical
Publication of DE722408C publication Critical patent/DE722408C/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/418—Preparation of metal complexes containing carboxylic acid moieties

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

Verfahren zur Herstellung eines neutralen komplexen Thorium-Natrium-tartra,ts Es ist bekannt, daß man durch Fällen von Thoriumnitratlösung mit Weinsäure, Auflösen des Niederschlages nach Zugabe von Ätzkali bzw. Ammoniak durch Erhitzen auf dem Wasserbad und Entfernung der entstandenen Nitrate durch Eindampfen und fraktionierte Kristallisation zu komplexen Thorium-Kalium- bzw. Thorium-Ammonium-tartraten gelangt (R o s e nheim, Samter und Davidsohn, Zeitschr. f. anorgan. Chemie 35 (19o3), S. 443).Process for the preparation of a neutral complex thorium sodium tartra, ts It is known that one can dissolve by precipitating thorium nitrate solution with tartaric acid of the precipitate after adding caustic potash or ammonia by heating on the Water bath and removal of the nitrates formed by evaporation and fractionation Crystallization leads to complex thorium-potassium or thorium-ammonium tartrates (R o s e nheim, Samter and Davidsohn, Zeitschr. F. Inorganic. Chemistry 35 (19o3), p. 443).

Das entsprechende komplexe Thorium-Natrium-tartrat konnte auf diesem Wege nicht rein erhalten werden, da es nicht vom Natriumnitrat zu trennen war.The corresponding complex thorium sodium tartrate could be based on this Ways could not be kept pure because it could not be separated from the sodium nitrate.

Es wurde nun gefunden, daß man zu einem reinen komplexen Thorium-Natrium-tartrat gelangt, indem man zunächst natronalkalische Lösungen von Thoriumtartrat, wie sie beispielsweise durch Auflösen von reinem Thoriumtartrat in Natronlauge erhalten werden, kurze Zeit erhitzt, darauf mit Weinsäure neutralisiert und nach dem Einengen kristallisieren läßt, wobei im Überschuß angewandtes Natriumhydroxyd als Natriumtartrat in Lösung bleibt. Man erhält auf diese Weise ein neutrales komplexes Th orium-Natrium-tartrat, aus dessen Lösungen dasThorium weder durch Ätzalkalien noch durch kohlensaure Alkalien fällbar ist.It has now been found that a pure complex thorium sodium tartrate can be obtained obtained by first using sodium-alkaline solutions of thorium tartrate, such as them obtained for example by dissolving pure thorium tartrate in sodium hydroxide solution are heated for a short time, then neutralized with tartaric acid and after concentrating lets crystallize, with sodium hydroxide used in excess as sodium tartrate remains in solution. In this way a neutral complex th orium sodium tartrate is obtained, from its solutions the thorium neither by caustic alkalis nor by carbonic acid alkalis is precipitable.

Das nach vorliegendem Verfahren hergestellte Produkt soll als Röntgenkontrastmittel Verwendung finden. Beispiel 84 Teile Thoriumtartrat werden mit 125 Teilen Wasser und 75 Raumteilen 2o Vol. °/oiger Natronlauge verrührt und auf dem Wasserbad erhitzt, bis eine klare Lösung entstanden ist. Diese wird noch i Stunde lang unter Rückfluß gekocht, dann mit Weinsäure neutralisiert und bis zur beginnenden Kristallisation eingeengt. Nach dem Erkalten, Absaugen, Waschen mit Methanol und Trocknen erhält man Ein schweres, weißes, kristallinisches Pulver von neutraler Reaktion, das sich im Verhältnis i ; 2 in Wasser löst. Es enthält 52 °(o Th02 und 7 0;o N a.The product manufactured according to the present process is intended as an X-ray contrast medium Find use. Example 84 parts of thorium tartrate are mixed with 125 parts of water and 75 parts by volume of 2o vol.% sodium hydroxide solution and stirred on the water bath heated, until a clear solution is obtained. This is refluxed for another hour boiled, then neutralized with tartaric acid and until crystallization begins constricted. After cooling, suction, washing with methanol and drying is obtained man A heavy, white, crystalline powder of neutral reaction, which in the ratio i; 2 dissolves in water. It contains 52 ° (o Th02 and 7 0; o N a.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines neutralen komplexen Thorium-Natrium-tartrats, dadurch gekennzeichnet, daß man reines Thoriumtartrat mit überschüssiger Natronlauge erhitzt, die so erhaltenen Lösungen mit Weinsäure neutralisiert und so «reit einengt, daß ein neutral reagierendes Komplexsalz auskristallisiert.PATENT CLAIM: Process for the production of a neutral complex Thorium sodium tartrate, characterized in that pure thorium tartrate is used heated with excess sodium hydroxide solution, the solutions thus obtained with tartaric acid neutralized and so narrow that a neutrally reacting complex salt crystallizes out.
DEC55873D 1940-06-27 1940-06-27 Process for the production of a neutral complex thorium sodium tartrate Expired DE722408C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEC55873D DE722408C (en) 1940-06-27 1940-06-27 Process for the production of a neutral complex thorium sodium tartrate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEC55873D DE722408C (en) 1940-06-27 1940-06-27 Process for the production of a neutral complex thorium sodium tartrate

Publications (1)

Publication Number Publication Date
DE722408C true DE722408C (en) 1942-07-09

Family

ID=7028222

Family Applications (1)

Application Number Title Priority Date Filing Date
DEC55873D Expired DE722408C (en) 1940-06-27 1940-06-27 Process for the production of a neutral complex thorium sodium tartrate

Country Status (1)

Country Link
DE (1) DE722408C (en)

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