DE69915297D1 - Vorrichtung und verfahren zur bestimmung von proteindomänegrenzen - Google Patents

Vorrichtung und verfahren zur bestimmung von proteindomänegrenzen

Info

Publication number
DE69915297D1
DE69915297D1 DE69915297T DE69915297T DE69915297D1 DE 69915297 D1 DE69915297 D1 DE 69915297D1 DE 69915297 T DE69915297 T DE 69915297T DE 69915297 T DE69915297 T DE 69915297T DE 69915297 D1 DE69915297 D1 DE 69915297D1
Authority
DE
Germany
Prior art keywords
protein domain
determining protein
protein
domain limits
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69915297T
Other languages
English (en)
Inventor
Aled Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affinium Pharmaceuticals Inc
Original Assignee
Affinium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinium Pharmaceuticals Inc filed Critical Affinium Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69915297D1 publication Critical patent/DE69915297D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69915297T 1998-07-15 1999-07-15 Vorrichtung und verfahren zur bestimmung von proteindomänegrenzen Expired - Lifetime DE69915297D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002243230A CA2243230A1 (en) 1998-07-15 1998-07-15 A device and method for the determination of protein domain boundaries
PCT/CA1999/000640 WO2000004384A1 (en) 1998-07-15 1999-07-15 Device and method for the determination of protein domain boundaries

Publications (1)

Publication Number Publication Date
DE69915297D1 true DE69915297D1 (de) 2004-04-08

Family

ID=4162664

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915297T Expired - Lifetime DE69915297D1 (de) 1998-07-15 1999-07-15 Vorrichtung und verfahren zur bestimmung von proteindomänegrenzen

Country Status (7)

Country Link
US (2) US6451591B1 (de)
EP (1) EP1097383B1 (de)
AT (1) ATE261127T1 (de)
AU (1) AU4597599A (de)
CA (1) CA2243230A1 (de)
DE (1) DE69915297D1 (de)
WO (1) WO2000004384A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2243230A1 (en) * 1998-07-15 2000-01-15 Aled Edwards A device and method for the determination of protein domain boundaries
US7300753B2 (en) * 1998-09-04 2007-11-27 John Rush Immunoaffinity isolation of modified peptides from complex mixtures
US7198896B2 (en) * 1998-09-04 2007-04-03 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
US20120244594A9 (en) * 1998-09-04 2012-09-27 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
US20110111424A1 (en) 2001-06-21 2011-05-12 Cell Signaling Technology, Inc. Analysis of ubiquitinated polypeptides
CA2460819A1 (en) * 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
DE10155693A1 (de) * 2001-11-07 2003-05-15 Florian Schweigert Verfahren zum Nachweis von apathogenen Partikeln und deren pathogenen Varianten im Organismus
DE10155692A1 (de) * 2001-11-07 2003-05-22 Florian Schweigert Verfahren zum Nachweis von endogenen und exogenen Stoffen im Organismus
US20040072356A1 (en) * 2002-02-20 2004-04-15 Guillermo Senisterra Methods and apparatuses for characterizing stability of biological molecules
US20050079526A1 (en) * 2002-02-20 2005-04-14 Affinium Pharmaceuticals, Inc. Methods and apparatuses for characterizing refolding and aggregation of biological molecules
US20050181464A1 (en) * 2002-04-04 2005-08-18 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from bacteria
US20040033530A1 (en) * 2002-04-08 2004-02-19 Awrey Donald E. High throughput purification, characterization and identification of recombinant proteins
US20040121445A1 (en) * 2002-07-31 2004-06-24 Fabien Marino Cell cultures
US6916455B2 (en) * 2002-08-14 2005-07-12 The Regents Of The University Of California Protein crystallography prescreen kit
US20060214104A1 (en) * 2004-10-26 2006-09-28 Invitrogen Corporation Compositions and methods for analyzing biomolecules using mass spectroscopy
US20150232540A1 (en) 2006-07-11 2015-08-20 Cell Signaling Technology, Inc. Analysis of ubiquitnated polypeptides
FR2939036B1 (fr) 2008-12-01 2010-12-17 Oreal Procede de coloration artificielle de la peau utilisant un melange de carotenoide et de colorant vert lidophile ; nouveau melange de colorants lipophiles ; composition
US9133450B2 (en) 2012-01-31 2015-09-15 University Of Calcutta Thermostable enzymes and methods of making and using the same
CN104535637B (zh) * 2014-12-11 2017-05-10 淮海工学院 一种胃蛋白酶酶解鉴定大分子胶原蛋白或明胶的方法
MX2018009339A (es) * 2016-02-04 2019-01-10 Oncobiologics Inc Métodos para la identificación y análisis de secuencias de aminoácidos de las proteínas.
US10544457B2 (en) * 2016-06-14 2020-01-28 Pacific Biosciences Of California, Inc. Methods and compositions for enriching compositions for polymerase enzyme complexes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3556945A (en) 1968-02-05 1971-01-19 Corning Glass Works Enzyme stabilization
US3519538A (en) 1968-09-05 1970-07-07 Corning Glass Works Chemically coupled enzymes
US3666627A (en) 1968-10-14 1972-05-30 Corning Glass Works Method of stabilizing enzymes
GB1536822A (en) 1976-05-31 1978-12-20 Sumitomo Chemical Co Immobilized non-specific proteases
JPH06172380A (ja) * 1992-12-04 1994-06-21 Shimadzu Corp ペプチドフラグメント分取装置
DE4403057C1 (de) * 1994-02-02 1994-12-08 Biotest Pharma Gmbh Thrombozytenstabilisierende Faktor IX-Fragmente, deren Herstellung sowie sie enthaltende Arzneimittel
US5856082A (en) * 1994-08-31 1999-01-05 University Of British Columbia Devices and methods for characterizing proteins and peptides
US6207370B1 (en) * 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
US6221626B1 (en) * 1998-06-30 2001-04-24 University Of Geneva Kit for electroblotting polypeptides separated on an electrophoresis gel
CA2243230A1 (en) * 1998-07-15 2000-01-15 Aled Edwards A device and method for the determination of protein domain boundaries
US7166441B2 (en) * 2002-03-12 2007-01-23 Perseptive Biosystems Inc. Method and apparatus for the identification and quantification of biomolecules

Also Published As

Publication number Publication date
EP1097383A1 (de) 2001-05-09
US20030104509A1 (en) 2003-06-05
AU4597599A (en) 2000-02-07
EP1097383B1 (de) 2004-03-03
US6451591B1 (en) 2002-09-17
CA2243230A1 (en) 2000-01-15
ATE261127T1 (de) 2004-03-15
WO2000004384A1 (en) 2000-01-27

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