DE69903346T2 - 22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität - Google Patents

22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität

Info

Publication number
DE69903346T2
DE69903346T2 DE69903346T DE69903346T DE69903346T2 DE 69903346 T2 DE69903346 T2 DE 69903346T2 DE 69903346 T DE69903346 T DE 69903346T DE 69903346 T DE69903346 T DE 69903346T DE 69903346 T2 DE69903346 T2 DE 69903346T2
Authority
DE
Germany
Prior art keywords
hydroxycholesta
alkyl
hydrogen
derivatives
meiose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69903346T
Other languages
English (en)
Other versions
DE69903346D1 (de
Inventor
Dirk Leysen
Der Louw Jaap Van
Gerard Hanssen
Anja Wiersma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1998/008130 external-priority patent/WO1999032506A1/en
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Application granted granted Critical
Publication of DE69903346D1 publication Critical patent/DE69903346D1/de
Publication of DE69903346T2 publication Critical patent/DE69903346T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69903346T 1998-12-11 1999-06-10 22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität Expired - Fee Related DE69903346T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1998/008130 WO1999032506A1 (en) 1997-12-18 1998-12-11 17β-ARYL (ARYLMETHYL) OXY(THIO)ALKYL -ANDROSTANE DERIVATIVES
PCT/EP1999/004099 WO2000035938A1 (en) 1998-12-11 1999-06-10 22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity

Publications (2)

Publication Number Publication Date
DE69903346D1 DE69903346D1 (de) 2002-11-07
DE69903346T2 true DE69903346T2 (de) 2003-01-30

Family

ID=8167154

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69903346T Expired - Fee Related DE69903346T2 (de) 1998-12-11 1999-06-10 22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität

Country Status (10)

Country Link
US (1) US6528501B1 (de)
EP (1) EP1137660B1 (de)
JP (1) JP2002532511A (de)
AT (1) ATE225366T1 (de)
AU (1) AU759344B2 (de)
CA (1) CA2352337A1 (de)
DE (1) DE69903346T2 (de)
DK (1) DK1137660T3 (de)
ES (1) ES2185360T3 (de)
WO (1) WO2000035938A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE246703T1 (de) * 1999-04-06 2003-08-15 Akzo Nobel Nv Oral wirksame 7-alpha-alkyl androgene

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
PL322106A1 (en) 1995-03-06 1998-01-05 Novo Nordisk As Meiosis stimulation
HUP9900454A3 (en) 1995-06-23 1999-11-29 Novo Nordisk As Meiosis regulating compounds and their use
IL130249A0 (en) 1996-12-20 2000-06-01 Novo Nordisk As Meiosis regulating compounds
ATE220686T1 (de) * 1997-12-18 2002-08-15 Akzo Nobel Nv 17beta-aryl(arylmethyl)oxy(thio)alkyl- androstanderivative

Also Published As

Publication number Publication date
AU759344B2 (en) 2003-04-10
DK1137660T3 (da) 2003-02-03
ATE225366T1 (de) 2002-10-15
EP1137660B1 (de) 2002-10-02
JP2002532511A (ja) 2002-10-02
ES2185360T3 (es) 2003-04-16
CA2352337A1 (en) 2000-06-22
WO2000035938A1 (en) 2000-06-22
US6528501B1 (en) 2003-03-04
EP1137660A1 (de) 2001-10-04
AU4610099A (en) 2000-07-03
DE69903346D1 (de) 2002-11-07

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: N.V. ORGANON, OSS, NL

8339 Ceased/non-payment of the annual fee