DE69839191D1 - Metall-komplexe mit antibakteriele und fungizide wirkungen - Google Patents

Metall-komplexe mit antibakteriele und fungizide wirkungen

Info

Publication number
DE69839191D1
DE69839191D1 DE69839191T DE69839191T DE69839191D1 DE 69839191 D1 DE69839191 D1 DE 69839191D1 DE 69839191 T DE69839191 T DE 69839191T DE 69839191 T DE69839191 T DE 69839191T DE 69839191 D1 DE69839191 D1 DE 69839191D1
Authority
DE
Germany
Prior art keywords
metal complexes
fungicidal effects
antibacterial targets
antibacterial
targets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69839191T
Other languages
English (en)
Other versions
DE69839191T2 (de
Inventor
Juan I Luengo
Stephen G Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ligand Pharmaceuticals Inc
SmithKline Beecham Corp
Original Assignee
Ligand Pharmaceuticals Inc
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ligand Pharmaceuticals Inc, SmithKline Beecham Corp filed Critical Ligand Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69839191D1 publication Critical patent/DE69839191D1/de
Publication of DE69839191T2 publication Critical patent/DE69839191T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69839191T 1997-10-31 1998-10-30 Metall-komplexe mit antibakteriele und fungizide wirkungen Expired - Lifetime DE69839191T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6540997P 1997-10-31 1997-10-31
US65409 1997-10-31
PCT/US1998/023049 WO1999022732A1 (en) 1997-10-31 1998-10-30 Novel metal complexes

Publications (2)

Publication Number Publication Date
DE69839191D1 true DE69839191D1 (de) 2008-04-10
DE69839191T2 DE69839191T2 (de) 2009-02-19

Family

ID=22062521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69839191T Expired - Lifetime DE69839191T2 (de) 1997-10-31 1998-10-30 Metall-komplexe mit antibakteriele und fungizide wirkungen

Country Status (8)

Country Link
US (1) US6211200B1 (de)
EP (1) EP1039906B1 (de)
JP (1) JP2001521895A (de)
AU (1) AU748063B2 (de)
CA (1) CA2308316A1 (de)
DE (1) DE69839191T2 (de)
ES (1) ES2301215T3 (de)
WO (1) WO1999022732A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU738473B2 (en) * 1997-10-31 2001-09-20 Glaxosmithkline Llc Novel metal complexes
US20090048318A1 (en) * 2003-04-29 2009-02-19 Connie Erickson-Miller Methods for treating degenerative diseases/injuries
EP1622609A4 (de) * 2003-04-29 2008-09-03 Smithkline Beecham Corp Verfahren zur behandlung von degenerativen erkrankungen/verletzungen
US20090143453A1 (en) * 2003-04-29 2009-06-04 Connie Erickson-Miller Methods for treating degenerative diseases/injuries
US20090298179A1 (en) * 2003-04-29 2009-12-03 Connie Erickson-Miller Methods For Treating Degenerative Diseases/Injuries
US20100004302A1 (en) * 2003-04-29 2010-01-07 Connie Erickson-Miller Methods for Treating Degenerative Diseases/Injuries

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830851A (en) 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5773569A (en) 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5693515A (en) 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US5767078A (en) 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US5981551A (en) * 1996-05-22 1999-11-09 Smithkline Beecham Corporation 2,5-diimino-3a,6a-diaryl-1,2,3,3a,4,5,6,6a-octahydroimidazo[4,5-d]imidazoles which are effective as G-CSF mimetics
AU9265698A (en) 1997-09-02 1999-03-22 Boehringer Mannheim Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing themand their use for the treatment and prevention of thrombocytopaenia and anaemia

Also Published As

Publication number Publication date
AU1369499A (en) 1999-05-24
ES2301215T3 (es) 2008-06-16
AU748063B2 (en) 2002-05-30
DE69839191T2 (de) 2009-02-19
CA2308316A1 (en) 1999-05-14
US6211200B1 (en) 2001-04-03
JP2001521895A (ja) 2001-11-13
WO1999022732A1 (en) 1999-05-14
EP1039906A4 (de) 2004-02-11
EP1039906B1 (de) 2008-02-27
EP1039906A1 (de) 2000-10-04

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Legal Events

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