DE69817860D1 - Für die i45f-mutation kodierende human app oder a4ct sequenzen - Google Patents

Für die i45f-mutation kodierende human app oder a4ct sequenzen

Info

Publication number
DE69817860D1
DE69817860D1 DE69817860T DE69817860T DE69817860D1 DE 69817860 D1 DE69817860 D1 DE 69817860D1 DE 69817860 T DE69817860 T DE 69817860T DE 69817860 T DE69817860 T DE 69817860T DE 69817860 D1 DE69817860 D1 DE 69817860D1
Authority
DE
Germany
Prior art keywords
a4ct
mutation
sequences encoding
human app
app
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69817860T
Other languages
English (en)
Other versions
DE69817860T2 (de
Inventor
Stefan Lichtenthaler
Konrad Beyreuther
Louis Masters
Frank Brown
David Allsop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Australia Pty Ltd
SmithKline Beecham Pharma GmbH and Co KG
SmithKline Beecham Ltd
Original Assignee
SMITHKLINE BEECHAM (AUSTRALIA) Pty Ltd DANDENONG
SmithKline Beecham Australia Pty Ltd
SmithKline Beecham Pharma GmbH and Co KG
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SMITHKLINE BEECHAM (AUSTRALIA) Pty Ltd DANDENONG, SmithKline Beecham Australia Pty Ltd, SmithKline Beecham Pharma GmbH and Co KG, SmithKline Beecham Ltd filed Critical SMITHKLINE BEECHAM (AUSTRALIA) Pty Ltd DANDENONG
Publication of DE69817860D1 publication Critical patent/DE69817860D1/de
Application granted granted Critical
Publication of DE69817860T2 publication Critical patent/DE69817860T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69817860T 1997-06-18 1998-06-09 Für die i45f-mutation kodierende human app oder a4ct sequenzen Expired - Lifetime DE69817860T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9712849.0A GB9712849D0 (en) 1997-06-18 1997-06-18 Compounds
GB9712849 1997-06-18
PCT/EP1998/003686 WO1998058060A1 (en) 1997-06-18 1998-06-09 Human app or a4ct sequences encoding the mutation 145f

Publications (2)

Publication Number Publication Date
DE69817860D1 true DE69817860D1 (de) 2003-10-09
DE69817860T2 DE69817860T2 (de) 2004-09-09

Family

ID=10814511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69817860T Expired - Lifetime DE69817860T2 (de) 1997-06-18 1998-06-09 Für die i45f-mutation kodierende human app oder a4ct sequenzen

Country Status (4)

Country Link
EP (1) EP1027433B1 (de)
DE (1) DE69817860T2 (de)
GB (1) GB9712849D0 (de)
WO (1) WO1998058060A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6815175B2 (en) 2001-03-16 2004-11-09 Cornell Research Foundation, Inc. Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder
GB0120344D0 (en) * 2001-08-21 2001-10-17 Smithkline Beecham Plc Compounds
GB0511861D0 (en) * 2005-06-13 2005-07-20 Merck Sharp & Dohme Proteins
WO2010117079A1 (ja) * 2009-04-10 2010-10-14 東亞合成株式会社 神経分化誘導ペプチド及びその利用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998003643A2 (en) * 1996-07-22 1998-01-29 Smithkline Beecham Pharma Gmbh Transgenic animals with mutant human app or a4ct sequences

Also Published As

Publication number Publication date
GB9712849D0 (en) 1997-08-20
WO1998058060A1 (en) 1998-12-23
EP1027433B1 (de) 2003-09-03
EP1027433A1 (de) 2000-08-16
DE69817860T2 (de) 2004-09-09

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SMITHKLINE BEECHAM PHARMA GMBH & CO. KG, 80993 MüN

Owner name: SMITHKLINE BEECHAM (AUSTRALIA) PTY LTD., BORONIA,

Owner name: SMITHKLINE BEECHAM PLC, BRENTFORD, MIDDLESEX, GB

8364 No opposition during term of opposition