DE69730607D1 - Fas ligand ähnliches protein, seine herstellung und verwendung - Google Patents

Fas ligand ähnliches protein, seine herstellung und verwendung

Info

Publication number
DE69730607D1
DE69730607D1 DE69730607T DE69730607T DE69730607D1 DE 69730607 D1 DE69730607 D1 DE 69730607D1 DE 69730607 T DE69730607 T DE 69730607T DE 69730607 T DE69730607 T DE 69730607T DE 69730607 D1 DE69730607 D1 DE 69730607D1
Authority
DE
Germany
Prior art keywords
protein
salt
partial peptide
fas ligand
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730607T
Other languages
English (en)
Other versions
DE69730607T2 (de
Inventor
Kazunori Nishi
Yukiko Hikichi
Yasushi Shintani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69730607D1 publication Critical patent/DE69730607D1/de
Application granted granted Critical
Publication of DE69730607T2 publication Critical patent/DE69730607T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69730607T 1996-07-19 1997-07-17 Fas ligand ähnliches protein, seine herstellung und verwendung Expired - Lifetime DE69730607T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP19120496 1996-07-19
JP19120496 1996-07-19
JP21169596 1996-08-09
JP21169596 1996-08-09
JP1933097 1997-01-31
JP1933097 1997-01-31
PCT/JP1997/002480 WO1998003648A1 (en) 1996-07-19 1997-07-17 Fas ligand-like protein, its production and use

Publications (2)

Publication Number Publication Date
DE69730607D1 true DE69730607D1 (de) 2004-10-14
DE69730607T2 DE69730607T2 (de) 2005-01-27

Family

ID=27282588

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730607T Expired - Lifetime DE69730607T2 (de) 1996-07-19 1997-07-17 Fas ligand ähnliches protein, seine herstellung und verwendung

Country Status (7)

Country Link
US (2) US6235878B1 (de)
EP (1) EP0922099B1 (de)
AT (1) ATE275630T1 (de)
AU (1) AU3461797A (de)
CA (1) CA2260767A1 (de)
DE (1) DE69730607T2 (de)
WO (1) WO1998003648A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
US7807783B1 (en) 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
EP0904278A4 (de) * 1996-03-22 1999-09-15 Human Genome Sciences Inc Apoptose-induzierendes molekül ii
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US6495520B2 (en) 1996-03-22 2002-12-17 Human Genome Sciences, Inc. Apoptosis Inducing Molecule II and methods of use
US6479254B2 (en) 1996-03-22 2002-11-12 Human Genome Sciences, Inc. Apoptosis inducing molecule II
CA2260767A1 (en) * 1996-07-19 1998-01-29 Takeda Chemical Industries, Ltd. Fas ligand-like protein, its production and use
US6998108B1 (en) 1997-07-07 2006-02-14 La Jolla Institute For Allergy And Immunology Antibodies to p30 polypeptides and methods making and using same
US6140467A (en) * 1997-07-07 2000-10-31 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US7118742B2 (en) 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6346388B1 (en) 1997-08-13 2002-02-12 Smithkline Beecham Corporation Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2
EP1054968A1 (de) * 1998-02-20 2000-11-29 Human Genome Sciences, Inc. Apoptose-induzierendes molekül ii, und verfahren zu seiner herstellung
WO2000024427A1 (fr) * 1998-10-28 2000-05-04 St. Marianna University School Of Medicine Remedes contre les rhumatismes contenant un gene fadd en qualite d'ingredient actif
CA2367315A1 (en) * 1999-03-11 2000-09-14 Human Genome Sciences, Inc. Apoptosis inducing molecule ii and methods of use
EP1179347A4 (de) * 1999-05-21 2002-06-26 Takeda Chemical Industries Ltd Kontrollsubstanzen für die leberfunktion
WO2001079496A2 (en) * 2000-03-13 2001-10-25 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
EP1273655A4 (de) * 2000-03-30 2004-08-04 Takeda Chemical Industries Ltd Verfahren zur herstellung eines rekombinanten proteins
AU5338701A (en) * 2000-04-12 2001-10-30 Jolla Inst Allergy Immunolog Ligand for herpes simplex virus entry mediator and methods of use
US20040058367A1 (en) * 2001-02-23 2004-03-25 Hideki Matsui Casoase 3 inhibitors
WO2002066049A1 (fr) * 2001-02-23 2002-08-29 Takeda Chemical Industries, Ltd. Agents pour changement plasmique
US20030078228A1 (en) * 2001-09-24 2003-04-24 Taylor Doris A. Fas Ligand
WO2003066834A2 (en) 2002-02-08 2003-08-14 Wyeth Composition and method for modulating an inflammatory response
EP1499353A4 (de) * 2002-04-15 2006-04-05 Human Genome Sciences Inc Spezifisch an tl5 bindende antikörper
ES2439994T3 (es) 2006-08-28 2014-01-27 Kyowa Hakko Kirin Co., Ltd. Anticuerpos antagonistas monoclonales humanos específicos de LIGHT humano
WO2008051612A2 (en) * 2006-10-25 2008-05-02 La Jolla Institute For Allergy And Immunology Light-mediated anti-cell proliferative compositions and methods
BRPI0720169A2 (pt) 2006-12-12 2013-12-24 Takeda Pharmaceutical Composto ou um sal do mesmo, prodroga, agente farmacêutico, método para a profilaxia ou tratamento de câncer, e, uso do composto
WO2008098183A2 (en) * 2007-02-08 2008-08-14 The University Of Chicago Combination therapy for treating cancer
WO2009113560A1 (ja) 2008-03-12 2009-09-17 武田薬品工業株式会社 縮合複素環化合物
US8734795B2 (en) * 2008-10-31 2014-05-27 Biogen Idec Ma Inc. Light targeting molecules and uses thereof
ME03564B (de) 2013-03-13 2020-07-20 Forma Therapeutics Inc Neuartige verbindungen und zusammensetzungen zur hemmung von fasn
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
CN113382633A (zh) 2018-10-29 2021-09-10 福马治疗股份有限公司 (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08127594A (ja) * 1993-11-10 1996-05-21 Mochida Pharmaceut Co Ltd Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
NZ279108A (en) * 1994-01-07 1997-06-24 Immunex Corp Human fas (tgf/ngf receptor) ligand proteins coding sequences and production
US5759536A (en) * 1994-05-27 1998-06-02 University Technology Corporation Use of fas ligand to supress T-lymphocyte-mediated immune responses
WO1997033899A1 (en) 1996-03-14 1997-09-18 Human Genome Sciences, Inc. Apoptosis inducing molecule i
ATE254135T1 (de) 1996-03-14 2003-11-15 Human Genome Sciences Inc Humaner tumornekrosefaktor delta und epsilon
EP0904278A4 (de) 1996-03-22 1999-09-15 Human Genome Sciences Inc Apoptose-induzierendes molekül ii
CA2260767A1 (en) * 1996-07-19 1998-01-29 Takeda Chemical Industries, Ltd. Fas ligand-like protein, its production and use

Also Published As

Publication number Publication date
EP0922099A1 (de) 1999-06-16
ATE275630T1 (de) 2004-09-15
CA2260767A1 (en) 1998-01-29
DE69730607T2 (de) 2005-01-27
EP0922099B1 (de) 2004-09-08
US6590090B1 (en) 2003-07-08
US6235878B1 (en) 2001-05-22
AU3461797A (en) 1998-02-10
WO1998003648A1 (en) 1998-01-29

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

8364 No opposition during term of opposition