DE69627150D1 - Verfahren zur herstellung von gegen e.coli bakterien der familie cs4-cfa/1 gerichteten antikörpern - Google Patents

Verfahren zur herstellung von gegen e.coli bakterien der familie cs4-cfa/1 gerichteten antikörpern

Info

Publication number
DE69627150D1
DE69627150D1 DE69627150T DE69627150T DE69627150D1 DE 69627150 D1 DE69627150 D1 DE 69627150D1 DE 69627150 T DE69627150 T DE 69627150T DE 69627150 T DE69627150 T DE 69627150T DE 69627150 D1 DE69627150 D1 DE 69627150D1
Authority
DE
Germany
Prior art keywords
cfa
family
consensus
peptide
coli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69627150T
Other languages
English (en)
Other versions
DE69627150T2 (de
Inventor
Frederick Cassels
Jeffrey Anderson
Mark Carter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Army
Original Assignee
US Department of Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Army filed Critical US Department of Army
Application granted granted Critical
Publication of DE69627150D1 publication Critical patent/DE69627150D1/de
Publication of DE69627150T2 publication Critical patent/DE69627150T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69627150T 1995-06-02 1996-06-03 Verfahren zur herstellung von gegen e.coli bakterien der familie cs4-cfa/1 gerichteten antikörpern Expired - Lifetime DE69627150T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/460,617 US5914114A (en) 1995-06-02 1995-06-02 Method of raising antibodies against E. coli of the family CS4-CFA/I
PCT/US1996/008730 WO1996038171A1 (en) 1995-06-02 1996-06-03 Methods of raising antibodies against e.coli of the family cs4-cfa/1

Publications (2)

Publication Number Publication Date
DE69627150D1 true DE69627150D1 (de) 2003-05-08
DE69627150T2 DE69627150T2 (de) 2004-01-29

Family

ID=23829417

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69627150T Expired - Lifetime DE69627150T2 (de) 1995-06-02 1996-06-03 Verfahren zur herstellung von gegen e.coli bakterien der familie cs4-cfa/1 gerichteten antikörpern

Country Status (8)

Country Link
US (1) US5914114A (de)
EP (1) EP0831900B1 (de)
AT (1) ATE235916T1 (de)
CA (1) CA2223013C (de)
DE (1) DE69627150T2 (de)
DK (1) DK0831900T3 (de)
ES (1) ES2196155T3 (de)
WO (1) WO1996038171A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734532B2 (en) * 1996-04-19 2001-06-14 Henry M. Jackson Foundation For The Advancement Of Military Medicine Histidine-tagged intimin and methods of using intimin to stimulate an immune response and as an antigen carrier with targeting capability
DE69737233D1 (de) * 1996-08-02 2007-02-22 Us Army Monoklonaler antikörper für die agglutinierung von e. coli, das ein protein der cs4/cfa-familie enthält
US7404961B2 (en) * 1996-08-02 2008-07-29 The United States Of America As Represented By The Secretary Of The Army Peptides responsive to antibodies against consensus peptide of the CS4-CFA/I family proteins
US7094883B1 (en) * 1996-08-02 2006-08-22 The United States Of America As Represented By The Secretary Of The Army Monoclonal antibody which agglutinates E. coli having the CS4-CFA/I family protein
JP4484968B2 (ja) * 1996-08-02 2010-06-16 デパートメント オブ ジ アーミー， ユー．エス． ガバメント Ｃｓ４―ｃｆａ／ｉファミリータンパク質のコンセンサスペプチドに対する抗体に応答性のペプチド
US6797276B1 (en) * 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
US7422747B2 (en) * 1997-10-07 2008-09-09 Loma Linda University Transgenic plant-based vaccines
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
AU4188100A (en) * 1999-04-08 2000-11-14 Gregory M. Glenn Dry formulation for transcutaneous immunization
AU6100500A (en) * 1999-07-15 2001-02-05 Med Immune, Inc. Fima pilus-based vaccines
AU7304000A (en) * 1999-09-22 2001-04-24 Isis Innovation Limited Virulence gene and protein, and their use
AU2001255543B2 (en) * 2000-04-20 2005-06-23 University Of Maryland, Baltimore Isolation and characterization of the csa operon (etec-cs4 pili) and methods of using same
IES20010042A2 (en) * 2001-01-19 2002-12-11 Enfer Technology Ltd Test for transmissible spongiform encephalopathies
US7527802B2 (en) * 2001-02-13 2009-05-05 The United States Of America As Represented By The Secretary Of The Army Vaccine for transcutaneous immunization
EP1481053B1 (de) * 2002-02-25 2007-09-12 US Army Medical Research & Materiel Command Verfahren zur herstellung von cs6-antigenimpfstoff zur behandlung, vorbeugung oder hemmung enterotoxigener escherichia coli-infektionen
JP5389438B2 (ja) * 2005-05-24 2014-01-15 アメリカ合衆国 抗アドヘシンに基づく受動免疫予防物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411888A (en) * 1981-06-22 1983-10-25 The University Of Rochester Composition of a novel immunogen for protection against diarrheal disease caused by enterotoxigenic Escherichia coli
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4971794A (en) * 1982-09-02 1990-11-20 Unilever Patent Holdings B.V. Production of antibodies using a mixture of strains of E. coli collectively expressing type I pili, CFA I pili, CFA II pili and K88 pili
US5417986A (en) * 1984-03-16 1995-05-23 The United States Of America As Represented By The Secretary Of The Army Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
US5017372A (en) * 1986-04-14 1991-05-21 Medicis Corporation Method of producing antibody-fortified dry whey
ES2042718T3 (es) * 1987-10-26 1993-12-16 Akzo Nv Procedimiento para la preparacion de una vacuna para proteger aves de corral contra septicemia producida por e. coli.
US5190746A (en) * 1989-05-10 1993-03-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Plaque inhibiting oligosaccharide
US5071977A (en) * 1989-05-10 1991-12-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Plaque inhibiting oligosaccharide
AU8417191A (en) * 1990-07-24 1992-02-18 Emory University Production of and compositions for the major cs1 pilin antigen including vaccines and diagnostic probes
US5698416A (en) * 1995-06-02 1997-12-16 The United States Of America As Represented By The Secretary Of The Army Methods for production of antigens under control of temperature-regulated promotors in enteric bacteria
US5637576A (en) * 1995-06-05 1997-06-10 Synsorb Biotech, Inc. Treatment of traveller's diarrhea
US5627163A (en) * 1995-06-05 1997-05-06 Synsorb Biotech, Inc. Treatment of traveller's diarrhea

Also Published As

Publication number Publication date
DE69627150T2 (de) 2004-01-29
US5914114A (en) 1999-06-22
WO1996038171A1 (en) 1996-12-05
EP0831900A4 (de) 1999-01-20
EP0831900B1 (de) 2003-04-02
ES2196155T3 (es) 2003-12-16
CA2223013A1 (en) 1996-12-05
DK0831900T3 (da) 2003-07-21
ATE235916T1 (de) 2003-04-15
EP0831900A1 (de) 1998-04-01
CA2223013C (en) 2011-03-22

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