DE69519564D1 - Verfahren zur herstellung von 4,4-dialkyl-6-halogen-chromanen oder -thiochromanen, welche als pharmazeutische zwischenprodukte brauchbar sind - Google Patents
Verfahren zur herstellung von 4,4-dialkyl-6-halogen-chromanen oder -thiochromanen, welche als pharmazeutische zwischenprodukte brauchbar sindInfo
- Publication number
- DE69519564D1 DE69519564D1 DE69519564T DE69519564T DE69519564D1 DE 69519564 D1 DE69519564 D1 DE 69519564D1 DE 69519564 T DE69519564 T DE 69519564T DE 69519564 T DE69519564 T DE 69519564T DE 69519564 D1 DE69519564 D1 DE 69519564D1
- Authority
- DE
- Germany
- Prior art keywords
- thiochromans
- chromanes
- useable
- dialkyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/183,543 US5420295A (en) | 1994-01-19 | 1994-01-19 | Process for preparing 4,4-dialkyl-6-halo-chromans or thiochromans useful as pharmaceutical intermediates |
PCT/US1995/000637 WO1995019973A2 (en) | 1994-01-19 | 1995-01-17 | Process for preparing 4,4-dialkyl-6-halo-chromans or thiochromans useful as pharmaceutical intermediates |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69519564D1 true DE69519564D1 (de) | 2001-01-11 |
DE69519564T2 DE69519564T2 (de) | 2001-05-17 |
Family
ID=22673255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69519564T Expired - Fee Related DE69519564T2 (de) | 1994-01-19 | 1995-01-17 | Verfahren zur herstellung von 4,4-dialkyl-6-halogen-chromanen oder -thiochromanen, welche als pharmazeutische zwischenprodukte brauchbar sind |
Country Status (8)
Country | Link |
---|---|
US (2) | US5420295A (de) |
EP (1) | EP0740665B1 (de) |
JP (1) | JP3872102B2 (de) |
AU (1) | AU1681895A (de) |
CA (1) | CA2181567C (de) |
DE (1) | DE69519564T2 (de) |
ES (1) | ES2153024T3 (de) |
WO (1) | WO1995019973A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA200100017A1 (ru) * | 1999-04-06 | 2001-08-27 | Америкэн Цианамид Компани | Способ дегалогенирования производных тиохромана и дигидробензотиофена |
WO2006040644A2 (en) * | 2004-10-11 | 2006-04-20 | Ranbaxy Laboratories Limited | Processes for the preparation of substituted thiochroman derivatives |
CN105924425B (zh) * | 2016-04-29 | 2018-06-05 | 浙江师范大学 | 一种制备二氢硫色满衍生物的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3434946A1 (de) * | 1984-09-22 | 1986-04-03 | Basf Ag, 6700 Ludwigshafen | Diarylacetylene, ihre herstellung und verwendung |
US4739098A (en) * | 1986-09-22 | 1988-04-19 | Allergan, Inc. | Ethynylphenyl-containing retinoic acid derivatives |
US5089509A (en) * | 1988-09-15 | 1992-02-18 | Allergan, Inc. | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity |
US4810804A (en) * | 1987-03-26 | 1989-03-07 | Allergan, Inc. | Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity |
US4895868A (en) * | 1988-06-29 | 1990-01-23 | Allergan, Inc. | Thiochroman esters of phenols and terephthallates having retinoid-like activity |
US5162546A (en) * | 1989-09-19 | 1992-11-10 | Allergan, Inc. | Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
US5023341A (en) * | 1989-09-19 | 1991-06-11 | Allergan, Inc. | Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity |
WO1992014725A1 (en) * | 1991-02-13 | 1992-09-03 | Allergan, Inc. | Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity |
-
1994
- 1994-01-19 US US08/183,543 patent/US5420295A/en not_active Expired - Lifetime
-
1995
- 1995-01-17 JP JP51962595A patent/JP3872102B2/ja not_active Expired - Fee Related
- 1995-01-17 WO PCT/US1995/000637 patent/WO1995019973A2/en active IP Right Grant
- 1995-01-17 EP EP95908537A patent/EP0740665B1/de not_active Expired - Lifetime
- 1995-01-17 AU AU16818/95A patent/AU1681895A/en not_active Abandoned
- 1995-01-17 CA CA002181567A patent/CA2181567C/en not_active Expired - Lifetime
- 1995-01-17 ES ES95908537T patent/ES2153024T3/es not_active Expired - Lifetime
- 1995-01-17 DE DE69519564T patent/DE69519564T2/de not_active Expired - Fee Related
- 1995-03-01 US US08/396,848 patent/US5519150A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH09508119A (ja) | 1997-08-19 |
US5519150A (en) | 1996-05-21 |
JP3872102B2 (ja) | 2007-01-24 |
US5420295A (en) | 1995-05-30 |
DE69519564T2 (de) | 2001-05-17 |
EP0740665B1 (de) | 2000-12-06 |
WO1995019973A2 (en) | 1995-07-27 |
EP0740665A1 (de) | 1996-11-06 |
AU1681895A (en) | 1995-08-08 |
WO1995019973A3 (en) | 1995-10-12 |
CA2181567C (en) | 2006-11-28 |
ES2153024T3 (es) | 2001-02-16 |
CA2181567A1 (en) | 1995-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |