DE69510825D1 - Verwendung von n-acylderivaten aminoalcoholen zur herstellung eines medikamentes zum ausübung neuroprotektiver wirkung bei neuropathologischen mit excitotoxizität verbundenen zuständen - Google Patents

Verwendung von n-acylderivaten aminoalcoholen zur herstellung eines medikamentes zum ausübung neuroprotektiver wirkung bei neuropathologischen mit excitotoxizität verbundenen zuständen

Info

Publication number
DE69510825D1
DE69510825D1 DE69510825T DE69510825T DE69510825D1 DE 69510825 D1 DE69510825 D1 DE 69510825D1 DE 69510825 T DE69510825 T DE 69510825T DE 69510825 T DE69510825 T DE 69510825T DE 69510825 D1 DE69510825 D1 DE 69510825D1
Authority
DE
Germany
Prior art keywords
acyl derivatives
aminoalcoholes
excitotoxicity
exercising
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69510825T
Other languages
English (en)
Inventor
Valle Francesco Della
Alberta Leon
Silvana Lorenzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LifeGroup SpA
Original Assignee
LifeGroup SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LifeGroup SpA filed Critical LifeGroup SpA
Application granted granted Critical
Publication of DE69510825D1 publication Critical patent/DE69510825D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
DE69510825T 1994-03-21 1995-03-17 Verwendung von n-acylderivaten aminoalcoholen zur herstellung eines medikamentes zum ausübung neuroprotektiver wirkung bei neuropathologischen mit excitotoxizität verbundenen zuständen Expired - Lifetime DE69510825D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI940523A IT1271623B (it) 1994-03-21 1994-03-21 N-acilderivati di aminoalcoli con acidi monocarbossilici e bicarbossilici con attivita' neuroprotettiva nelle patologie neurologiche correlate ad eccitotossicita'
PCT/EP1995/001002 WO1995025509A2 (en) 1994-03-21 1995-03-17 Use of n-acyl derivatives of aminoalcohols in the manufacture of a medicament for practising neuroprotective action in neuropathological states connected with excitotoxicity

Publications (1)

Publication Number Publication Date
DE69510825D1 true DE69510825D1 (de) 1999-08-19

Family

ID=11368280

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69510825T Expired - Lifetime DE69510825D1 (de) 1994-03-21 1995-03-17 Verwendung von n-acylderivaten aminoalcoholen zur herstellung eines medikamentes zum ausübung neuroprotektiver wirkung bei neuropathologischen mit excitotoxizität verbundenen zuständen

Country Status (8)

Country Link
US (1) US5925678A (de)
EP (1) EP0804179B1 (de)
JP (1) JPH09510467A (de)
AT (1) ATE182075T1 (de)
AU (1) AU2109095A (de)
DE (1) DE69510825D1 (de)
IT (1) IT1271623B (de)
WO (1) WO1995025509A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271266B (it) * 1994-12-14 1997-05-27 Valle Francesco Della Impiego terapeutico di ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi
US6410597B1 (en) * 2000-02-25 2002-06-25 Virginia Commonwealth University Hydroxyalkyl amide analogs of ceramide
WO2004096256A1 (en) * 2001-01-23 2004-11-11 The United States Of America, As Represented By The Secretary Of The Navy Methods for preventing and treating loss of balance function due to oxidative stress
CN1788722A (zh) * 2001-05-23 2006-06-21 钱吉子 预防和治疗痴呆的组合物
ITMI20011483A1 (it) * 2001-07-11 2003-01-11 Res & Innovation Soc Coop A R Uso di composti come antagonisti funzionali ai recettori centrali deicannabinoidi
DE10351111A1 (de) * 2003-11-03 2005-06-16 Langlotz, Rainer Arzneimittel und Verfahren zu ihrer Herstellung
JP7041673B2 (ja) * 2016-10-13 2022-03-24 カーノット， エルエルシー Ｎ－アシルエタノールアミド誘導体およびその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6183147A (ja) * 1984-09-28 1986-04-26 Nippon Chemiphar Co Ltd 新規なアミノアルコール誘導体およびその製造法並びにそれを有効成分とするグルタミン酸遮断剤
US5227397A (en) * 1989-04-28 1993-07-13 Pfizer Inc. Polyamines and polypeptides useful as antagonists of excitatory amino acid neuro-transmitters and/or as blockers of calcium channels
IT1252866B (it) * 1991-12-31 1995-06-28 Lifegroup Spa N-acilderivati di aminoalcooli con acidi policarbossilici atti alla modulazione dei mastociti nei processi infiammatori su base neuroimmunogenica
US5618842A (en) * 1991-12-31 1997-04-08 Lifegroup S.P.A. N-acyl derivatives of aminoalcohols with polycarboxylic acids able to modulate mast cells in inflammatory processes having neuroimmunogenic origin
IT1257697B (it) * 1992-04-24 1996-02-01 Lifegroup Spa N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
WO1993025203A1 (en) * 1992-06-17 1993-12-23 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo[a,d]cyclohepten-5,10-imine

Also Published As

Publication number Publication date
ITMI940523A1 (it) 1995-09-21
EP0804179A2 (de) 1997-11-05
AU2109095A (en) 1995-10-09
US5925678A (en) 1999-07-20
JPH09510467A (ja) 1997-10-21
EP0804179B1 (de) 1999-07-14
WO1995025509A3 (en) 1995-10-12
WO1995025509A2 (en) 1995-09-28
IT1271623B (it) 1997-06-04
ITMI940523A0 (it) 1994-03-21
ATE182075T1 (de) 1999-07-15

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