DE69413606D1 - Endothelinantagonistische Peptide - Google Patents
Endothelinantagonistische PeptideInfo
- Publication number
- DE69413606D1 DE69413606D1 DE69413606T DE69413606T DE69413606D1 DE 69413606 D1 DE69413606 D1 DE 69413606D1 DE 69413606 T DE69413606 T DE 69413606T DE 69413606 T DE69413606 T DE 69413606T DE 69413606 D1 DE69413606 D1 DE 69413606D1
- Authority
- DE
- Germany
- Prior art keywords
- antagonistic peptides
- endothelin antagonistic
- endothelin
- peptides
- antagonistic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15790793 | 1993-06-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69413606D1 true DE69413606D1 (de) | 1998-11-05 |
DE69413606T2 DE69413606T2 (de) | 1999-04-15 |
Family
ID=15660055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69413606T Expired - Fee Related DE69413606T2 (de) | 1993-06-03 | 1994-06-01 | Endothelinantagonistische Peptide |
Country Status (5)
Country | Link |
---|---|
US (1) | US5494897A (de) |
EP (1) | EP0632052B1 (de) |
AU (1) | AU673731B2 (de) |
CA (1) | CA2124989A1 (de) |
DE (1) | DE69413606T2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5430022A (en) * | 1990-05-14 | 1995-07-04 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound and its preparation |
US5614497A (en) * | 1991-12-27 | 1997-03-25 | Takeda Chemical Industries, Ltd. | Peptide, production and use thereof |
PT1165613E (pt) | 1999-03-29 | 2008-07-29 | Procter & Gamble | Ligantes do receptor de melanocortina |
FR2913978B1 (fr) * | 2007-03-21 | 2009-07-03 | Centre Nat Rech Scient | Procede de synthese de peptides sans solvant |
US9822157B2 (en) | 2013-03-15 | 2017-11-21 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
DK3143037T3 (da) | 2014-05-16 | 2021-09-20 | Protagonist Therapeutics Inc | Alpha4beta7-integrin-thioether-peptidantagonister |
EP3169403B1 (de) | 2014-07-17 | 2024-02-14 | Protagonist Therapeutics, Inc. | Orale peptidinhibitoren des interleukin-23-rezeptors und deren verwendung zur behandlung von entzündlichen darmerkrankungen |
SG11201702553RA (en) | 2014-10-01 | 2017-04-27 | Protagonist Therapeutics Inc | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
US11753443B2 (en) | 2018-02-08 | 2023-09-12 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
JP2021530477A (ja) * | 2018-07-12 | 2021-11-11 | プロタゴニスト セラピューティクス, インコーポレイテッド | インターロイキン−23受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用 |
CN114341161A (zh) | 2019-07-10 | 2022-04-12 | 领导医疗有限公司 | 白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途 |
JP7441955B2 (ja) | 2020-01-15 | 2024-03-01 | ヤンセン バイオテツク,インコーポレーテツド | インターロイキン23受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用 |
MX2023005994A (es) | 2020-11-20 | 2023-08-11 | Janssen Pharmaceutica Nv | Composiciones de inhibidores peptidicos del receptor de interleucina-23. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2032559C (en) * | 1989-12-28 | 2001-11-06 | Kiyofumi Ishikawa | Endothelin antagonistic cyclic pentapeptides |
CA2043741C (en) * | 1990-06-07 | 2003-04-01 | Kiyofumi Ishikawa | Endothelin antagonistic peptide derivatives |
US5144918A (en) * | 1990-07-19 | 1992-09-08 | Mazda Motor Corporation | Intake system for engine |
GB9300048D0 (en) * | 1993-01-04 | 1993-03-03 | Wellcome Found | Endothelin converting enzyme inhibitors |
-
1994
- 1994-05-31 AU AU63454/94A patent/AU673731B2/en not_active Ceased
- 1994-06-01 EP EP94108462A patent/EP0632052B1/de not_active Expired - Lifetime
- 1994-06-01 DE DE69413606T patent/DE69413606T2/de not_active Expired - Fee Related
- 1994-06-02 CA CA002124989A patent/CA2124989A1/en not_active Abandoned
- 1994-06-03 US US08/253,775 patent/US5494897A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU673731B2 (en) | 1996-11-21 |
DE69413606T2 (de) | 1999-04-15 |
EP0632052B1 (de) | 1998-09-30 |
EP0632052A1 (de) | 1995-01-04 |
AU6345494A (en) | 1994-12-22 |
CA2124989A1 (en) | 1994-12-04 |
US5494897A (en) | 1996-02-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |