DE69410465D1 - Verfahren zur herstellung von thiopyranen - Google Patents
Verfahren zur herstellung von thiopyranenInfo
- Publication number
- DE69410465D1 DE69410465D1 DE69410465T DE69410465T DE69410465D1 DE 69410465 D1 DE69410465 D1 DE 69410465D1 DE 69410465 T DE69410465 T DE 69410465T DE 69410465 T DE69410465 T DE 69410465T DE 69410465 D1 DE69410465 D1 DE 69410465D1
- Authority
- DE
- Germany
- Prior art keywords
- thiopyrans
- producing
- preparation
- intermediates
- properties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000004882 thiopyrans Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939314133A GB9314133D0 (en) | 1993-07-08 | 1993-07-08 | New process |
| PCT/GB1994/001472 WO1995001978A1 (en) | 1993-07-08 | 1994-07-07 | Process for thiopyrans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69410465D1 true DE69410465D1 (de) | 1998-06-25 |
| DE69410465T2 DE69410465T2 (de) | 1998-10-08 |
Family
ID=10738488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69410465T Expired - Lifetime DE69410465T2 (de) | 1993-07-08 | 1994-07-07 | Verfahren zur herstellung von thiopyranen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5780636A (de) |
| EP (1) | EP0707583B1 (de) |
| JP (1) | JPH08512309A (de) |
| AT (1) | ATE166351T1 (de) |
| AU (1) | AU7080794A (de) |
| DE (1) | DE69410465T2 (de) |
| GB (1) | GB9314133D0 (de) |
| IL (1) | IL110244A0 (de) |
| WO (1) | WO1995001978A1 (de) |
| ZA (1) | ZA944981B (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2528849B1 (fr) * | 1982-06-17 | 1985-06-21 | Rhone Poulenc Sante | Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent |
| FR2653770B1 (fr) * | 1989-10-31 | 1992-01-03 | Rhone Poulenc Sante | Procede de preparation de (pyridyl-3)-2 tetrahydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r), les (pyridyl-3)-2 tetrhydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r) ainsi obtenus et les compositions pharmaceutiques qui les contiennent. |
-
1993
- 1993-07-08 GB GB939314133A patent/GB9314133D0/en active Pending
-
1994
- 1994-07-07 EP EP94919783A patent/EP0707583B1/de not_active Expired - Lifetime
- 1994-07-07 JP JP7503917A patent/JPH08512309A/ja active Pending
- 1994-07-07 AU AU70807/94A patent/AU7080794A/en not_active Abandoned
- 1994-07-07 IL IL11024494A patent/IL110244A0/xx unknown
- 1994-07-07 WO PCT/GB1994/001472 patent/WO1995001978A1/en active IP Right Grant
- 1994-07-07 AT AT94919783T patent/ATE166351T1/de not_active IP Right Cessation
- 1994-07-07 DE DE69410465T patent/DE69410465T2/de not_active Expired - Lifetime
- 1994-07-08 ZA ZA944981A patent/ZA944981B/xx unknown
-
1996
- 1996-01-05 US US08/583,363 patent/US5780636A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IL110244A0 (en) | 1994-10-21 |
| AU7080794A (en) | 1995-02-06 |
| DE69410465T2 (de) | 1998-10-08 |
| WO1995001978A1 (en) | 1995-01-19 |
| US5780636A (en) | 1998-07-14 |
| ZA944981B (en) | 1995-02-21 |
| ATE166351T1 (de) | 1998-06-15 |
| JPH08512309A (ja) | 1996-12-24 |
| EP0707583A1 (de) | 1996-04-24 |
| GB9314133D0 (en) | 1993-08-18 |
| EP0707583B1 (de) | 1998-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: AVENTIS PHARMA LTD., WEST MALLING, KENT, GB |