DE69409553T2 - Zytotoxische Verbindungen - Google Patents
Zytotoxische VerbindungenInfo
- Publication number
- DE69409553T2 DE69409553T2 DE69409553T DE69409553T DE69409553T2 DE 69409553 T2 DE69409553 T2 DE 69409553T2 DE 69409553 T DE69409553 T DE 69409553T DE 69409553 T DE69409553 T DE 69409553T DE 69409553 T2 DE69409553 T2 DE 69409553T2
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- cytotoxic compounds
- mpta
- antitumor
- formulae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/02—1,2-Dioxanes; Hydrogenated 1,2-dioxanes
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939302044A GB9302044D0 (en) | 1993-02-03 | 1993-02-03 | Cytotoxic compounds i |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69409553D1 DE69409553D1 (de) | 1998-05-20 |
| DE69409553T2 true DE69409553T2 (de) | 1998-10-15 |
Family
ID=10729726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69409553T Expired - Fee Related DE69409553T2 (de) | 1993-02-03 | 1994-02-02 | Zytotoxische Verbindungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5449684A (de) |
| EP (1) | EP0610076B1 (de) |
| JP (1) | JPH0769884A (de) |
| AT (1) | ATE165094T1 (de) |
| AU (1) | AU674366B2 (de) |
| CA (1) | CA2114777A1 (de) |
| DE (1) | DE69409553T2 (de) |
| DK (1) | DK0610076T3 (de) |
| ES (1) | ES2116522T3 (de) |
| GB (1) | GB9302044D0 (de) |
| ZA (1) | ZA94746B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541515B2 (en) * | 2000-08-09 | 2003-04-01 | Merck & Co., Inc. | HIV integrase inhibitors |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4731377A (en) * | 1986-01-31 | 1988-03-15 | Harbor Branch Oceanographic Institute, Inc. | Antitumor cyclic peroxides |
| US5183924A (en) * | 1989-01-24 | 1993-02-02 | Lipha, Lyonnaise Industrielle Pharmaceutique | Derivatives of benzocycloalkenyldihydroxyalkanoic acids, processes of preparation and medications containing them |
-
1993
- 1993-02-03 GB GB939302044A patent/GB9302044D0/en active Pending
-
1994
- 1994-02-02 CA CA002114777A patent/CA2114777A1/en not_active Abandoned
- 1994-02-02 DE DE69409553T patent/DE69409553T2/de not_active Expired - Fee Related
- 1994-02-02 ES ES94300778T patent/ES2116522T3/es not_active Expired - Lifetime
- 1994-02-02 EP EP94300778A patent/EP0610076B1/de not_active Expired - Lifetime
- 1994-02-02 AT AT94300778T patent/ATE165094T1/de not_active IP Right Cessation
- 1994-02-02 DK DK94300778T patent/DK0610076T3/da active
- 1994-02-03 US US08/191,336 patent/US5449684A/en not_active Expired - Fee Related
- 1994-02-03 ZA ZA94746A patent/ZA94746B/xx unknown
- 1994-02-03 AU AU54910/94A patent/AU674366B2/en not_active Ceased
- 1994-02-03 JP JP6043023A patent/JPH0769884A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB9302044D0 (en) | 1993-03-24 |
| AU674366B2 (en) | 1996-12-19 |
| JPH0769884A (ja) | 1995-03-14 |
| AU5491094A (en) | 1994-08-11 |
| EP0610076B1 (de) | 1998-04-15 |
| DE69409553D1 (de) | 1998-05-20 |
| ES2116522T3 (es) | 1998-07-16 |
| CA2114777A1 (en) | 1994-08-04 |
| ATE165094T1 (de) | 1998-05-15 |
| DK0610076T3 (da) | 1999-01-25 |
| US5449684A (en) | 1995-09-12 |
| ZA94746B (en) | 1994-09-29 |
| EP0610076A1 (de) | 1994-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |