DE69325452D1 - METHOD FOR PRODUCING (S) -3-AMINO-1-SUBSTITUTED PIRROLIDINE - Google Patents

METHOD FOR PRODUCING (S) -3-AMINO-1-SUBSTITUTED PIRROLIDINE

Info

Publication number
DE69325452D1
DE69325452D1 DE69325452T DE69325452T DE69325452D1 DE 69325452 D1 DE69325452 D1 DE 69325452D1 DE 69325452 T DE69325452 T DE 69325452T DE 69325452 T DE69325452 T DE 69325452T DE 69325452 D1 DE69325452 D1 DE 69325452D1
Authority
DE
Germany
Prior art keywords
pirrolidine
amino
substituted
producing
propionylaminoü
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69325452T
Other languages
German (de)
Other versions
DE69325452T2 (en
Inventor
Tung Van Le
F Spence
James Wemple
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of DE69325452D1 publication Critical patent/DE69325452D1/en
Application granted granted Critical
Publication of DE69325452T2 publication Critical patent/DE69325452T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

1-Benzyl-3(S)-Ä2-(S)-(tert.-butoxy-carbonylamino) propionylaminoÜ-pyrrolidine and its use as an intermediate.
DE69325452T 1992-04-27 1993-04-16 METHOD FOR PRODUCING (S) -3-AMINO-1-SUBSTITUTED PIRROLIDINE Expired - Fee Related DE69325452T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/874,657 US5177217A (en) 1992-04-27 1992-04-27 Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
PCT/US1993/003646 WO1993022283A1 (en) 1992-04-27 1993-04-16 Process for the manufacture of (s)-3-amino-1-substituted-pyrrolidines

Publications (2)

Publication Number Publication Date
DE69325452D1 true DE69325452D1 (en) 1999-07-29
DE69325452T2 DE69325452T2 (en) 2000-05-18

Family

ID=25364272

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69325452T Expired - Fee Related DE69325452T2 (en) 1992-04-27 1993-04-16 METHOD FOR PRODUCING (S) -3-AMINO-1-SUBSTITUTED PIRROLIDINE

Country Status (20)

Country Link
US (1) US5177217A (en)
EP (2) EP0911322A3 (en)
JP (1) JP3264928B2 (en)
KR (1) KR950701316A (en)
AT (1) ATE181549T1 (en)
AU (1) AU666736B2 (en)
CA (1) CA2133091C (en)
CZ (1) CZ285593B6 (en)
DE (1) DE69325452T2 (en)
DK (1) DK0638068T3 (en)
ES (1) ES2135477T3 (en)
FI (1) FI106122B (en)
GR (1) GR3031149T3 (en)
HU (1) HU220603B1 (en)
MX (1) MX9302414A (en)
NO (1) NO300969B1 (en)
NZ (1) NZ252850A (en)
RU (1) RU2101279C1 (en)
SK (1) SK281195B6 (en)
WO (1) WO1993022283A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines
EP1138672A1 (en) * 1998-01-12 2001-10-04 Basilea Pharmaceutica AG Process for the preparation of 3-amino-pyrrolidine derivatives
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives
KR20010100965A (en) 1998-11-02 2001-11-14 가마꾸라 아끼오 Pyrrolidine compounds and medicinal utilization thereof
US6531594B2 (en) 2000-08-24 2003-03-11 Mitsubishi Chemical Corporation Process for producing 1H-3-aminopyrrolidine and derivatives thereof
JP4481659B2 (en) 2002-03-29 2010-06-16 株式会社カネカ Method for improving optical purity of 1-benzyl-3-aminopyrrolidine and salt used therefor
EP1676837A4 (en) * 2003-10-08 2008-09-10 Teijin Pharma Ltd Process for producing aminopyrrolidine derivative and intermediate compound
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
US8247442B2 (en) 2006-03-29 2012-08-21 Purdue Pharma L.P. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
WO2007118853A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
US8399486B2 (en) 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
WO2009040659A2 (en) 2007-09-28 2009-04-02 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
CN111620802A (en) * 2020-06-18 2020-09-04 山西千岫制药有限公司 Preparation method of cefditoren intermediate (R) -1-benzyl-3-aminopyrrolidine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785119A (en) * 1985-10-11 1988-11-15 Tokyo Kasei Kogyo Co., Ltd. 3-aminopyrrolidine compound and process for preparation thereof
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP2995704B2 (en) * 1989-02-17 1999-12-27 東京化成工業株式会社 Method for producing optically active 1H-3-aminopyrrolidine compound
US4916141A (en) * 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
HU208005B (en) * 1990-02-19 1993-07-28 Kyorin Seiyaku Kk Process for producing optically active 8-methoxy-quinolone-carboxylic acid derivatives and pharmaceutical compositions containing them
US5177217A (en) * 1992-04-27 1993-01-05 Warner-Lambert Company Process for the manufacture of (S)-3-amino-1-substituted-pyrrolidines

Also Published As

Publication number Publication date
RU94046013A (en) 1996-10-10
HUT70218A (en) 1995-09-28
EP0911322A3 (en) 2001-06-13
CZ285593B6 (en) 1999-09-15
FI945000A0 (en) 1994-10-24
ES2135477T3 (en) 1999-11-01
EP0638068B1 (en) 1999-06-23
NO300969B1 (en) 1997-08-25
NZ252850A (en) 1996-10-28
NO944075D0 (en) 1994-10-26
HU220603B1 (en) 2002-03-28
AU4289993A (en) 1993-11-29
CZ257694A3 (en) 1995-10-18
US5177217A (en) 1993-01-05
CA2133091A1 (en) 1993-11-11
JP3264928B2 (en) 2002-03-11
EP0638068A1 (en) 1995-02-15
FI945000A (en) 1994-10-24
DK0638068T3 (en) 1999-11-22
DE69325452T2 (en) 2000-05-18
KR950701316A (en) 1995-03-23
FI106122B (en) 2000-11-30
SK281195B6 (en) 2001-01-18
GR3031149T3 (en) 1999-12-31
JPH07506110A (en) 1995-07-06
ATE181549T1 (en) 1999-07-15
CA2133091C (en) 2005-01-04
AU666736B2 (en) 1996-02-22
EP0911322A2 (en) 1999-04-28
MX9302414A (en) 1993-10-01
RU2101279C1 (en) 1998-01-10
WO1993022283A1 (en) 1993-11-11
SK129894A3 (en) 1995-05-10
NO944075L (en) 1994-12-27

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8339 Ceased/non-payment of the annual fee