DE69317428T2 - METHOD FOR INHIBITING HIV REPLICATION USING IL-4 - Google Patents

METHOD FOR INHIBITING HIV REPLICATION USING IL-4

Info

Publication number
DE69317428T2
DE69317428T2 DE69317428T DE69317428T DE69317428T2 DE 69317428 T2 DE69317428 T2 DE 69317428T2 DE 69317428 T DE69317428 T DE 69317428T DE 69317428 T DE69317428 T DE 69317428T DE 69317428 T2 DE69317428 T2 DE 69317428T2
Authority
DE
Germany
Prior art keywords
pct
hiv replication
inhibiting hiv
sec
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69317428T
Other languages
German (de)
Other versions
DE69317428D1 (en
Inventor
Jerome Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE69317428D1 publication Critical patent/DE69317428D1/en
Application granted granted Critical
Publication of DE69317428T2 publication Critical patent/DE69317428T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

PCT No. PCT/US93/07587 Sec. 371 Date Feb. 16, 1995 Sec. 102(e) Date Feb. 16, 1995 PCT Filed Aug. 17, 1993 PCT Pub. No. WO94/04179 PCT Pub. Date Mar. 3, 1994This invention provides a method for inhibiting HIV replication in a patient which comprises administering to a patient infected with HIV a therapeutically effective amount of IL-4.
DE69317428T 1992-08-19 1993-08-17 METHOD FOR INHIBITING HIV REPLICATION USING IL-4 Expired - Fee Related DE69317428T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93213492A 1992-08-19 1992-08-19
PCT/US1993/007587 WO1994004179A1 (en) 1992-08-19 1993-08-17 Method for inhibiting hiv replication using il-4

Publications (2)

Publication Number Publication Date
DE69317428D1 DE69317428D1 (en) 1998-04-16
DE69317428T2 true DE69317428T2 (en) 1998-07-02

Family

ID=25461831

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69317428T Expired - Fee Related DE69317428T2 (en) 1992-08-19 1993-08-17 METHOD FOR INHIBITING HIV REPLICATION USING IL-4

Country Status (22)

Country Link
US (1) US5700461A (en)
EP (1) EP0656785B1 (en)
JP (1) JP2711182B2 (en)
KR (1) KR950702838A (en)
CN (1) CN1086437A (en)
AT (1) ATE163860T1 (en)
AU (1) AU683427B2 (en)
CA (1) CA2142862C (en)
CZ (1) CZ38095A3 (en)
DE (1) DE69317428T2 (en)
ES (1) ES2113549T3 (en)
FI (1) FI950696A (en)
HU (1) HUT72709A (en)
IL (1) IL106717A0 (en)
MX (1) MX9305016A (en)
NO (1) NO950599D0 (en)
NZ (1) NZ255735A (en)
PL (1) PL307508A1 (en)
SK (1) SK21295A3 (en)
TW (1) TW291439B (en)
WO (1) WO1994004179A1 (en)
ZA (1) ZA936018B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000507917A (en) * 1995-11-02 2000-06-27 シェーリング コーポレイション Continuous low-dose cytokine infusion therapy
US20040132161A1 (en) * 1998-04-20 2004-07-08 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness
US20030232738A1 (en) * 1998-04-20 2003-12-18 National Jewish Medical And Research Center Method and composition for increasing CD4+ T lymphocyte immune responsiveness
US20050124645A1 (en) * 1998-04-20 2005-06-09 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness
MXPA00012842A (en) * 1998-06-24 2004-06-22 Univ Emory Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv.
US6734192B1 (en) * 1999-08-23 2004-05-11 Mp-1 Inc. Treatment of viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
JPH02485A (en) * 1987-08-03 1990-01-05 Yuu Honshiyo Novel human interleukin-4, recombination vector for manifesting the same factor and transformant transformed by the same vector
US5011829A (en) * 1989-06-02 1991-04-30 G. D. Searle & Co. Pharmaceutical composition and method of inhibiting virus
ES2082201T3 (en) * 1990-03-21 1996-03-16 Schering Corp USE OF IL-4 TO IMPROVE THE IMMUNE RESPONSE TO INFECTIOUS ANTIGEN TESTS.
US5206345A (en) * 1990-08-02 1993-04-27 Fred Hutchinson Cancer Research Center Il-4 and tnf induce mab 6g10-recognized expression on bone marrow stromal cells
EP0490006B1 (en) * 1990-12-13 1994-06-22 Schering-Plough Pharmaceutical compositions for the treatment of B-cell malignancies

Also Published As

Publication number Publication date
SK21295A3 (en) 1997-01-08
CZ38095A3 (en) 1995-12-13
ZA936018B (en) 1994-06-13
TW291439B (en) 1996-11-21
EP0656785B1 (en) 1998-03-11
ATE163860T1 (en) 1998-03-15
FI950696A0 (en) 1995-02-16
HUT72709A (en) 1996-05-28
KR950702838A (en) 1995-08-23
JP2711182B2 (en) 1998-02-10
NO950599L (en) 1995-02-17
HU9500487D0 (en) 1995-04-28
IL106717A0 (en) 1993-12-08
CN1086437A (en) 1994-05-11
AU683427B2 (en) 1997-11-13
AU5007593A (en) 1994-03-15
JPH07506116A (en) 1995-07-06
ES2113549T3 (en) 1998-05-01
DE69317428D1 (en) 1998-04-16
CA2142862A1 (en) 1994-03-03
EP0656785A1 (en) 1995-06-14
FI950696A (en) 1995-02-16
NO950599D0 (en) 1995-02-17
MX9305016A (en) 1994-02-28
CA2142862C (en) 2000-05-30
WO1994004179A1 (en) 1994-03-03
US5700461A (en) 1997-12-23
PL307508A1 (en) 1995-05-29
NZ255735A (en) 1997-06-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee