DE69310182D1 - Interleukin-4 stimulierter t-lymphozyten-zelltod - Google Patents
Interleukin-4 stimulierter t-lymphozyten-zelltodInfo
- Publication number
- DE69310182D1 DE69310182D1 DE69310182T DE69310182T DE69310182D1 DE 69310182 D1 DE69310182 D1 DE 69310182D1 DE 69310182 T DE69310182 T DE 69310182T DE 69310182 T DE69310182 T DE 69310182T DE 69310182 D1 DE69310182 D1 DE 69310182D1
- Authority
- DE
- Germany
- Prior art keywords
- interleukin
- population
- stimulated
- cell death
- lymphocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92629092A | 1992-08-10 | 1992-08-10 | |
PCT/US1993/007471 WO1994003202A1 (en) | 1992-08-10 | 1993-08-10 | Interleukin-4 stimulated t lymphocyte cell death |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69310182D1 true DE69310182D1 (de) | 1997-05-28 |
DE69310182T2 DE69310182T2 (de) | 1997-12-04 |
Family
ID=25453003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69310182T Expired - Lifetime DE69310182T2 (de) | 1992-08-10 | 1993-08-10 | Interleukin-4 stimulierter t-lymphozyten-zelltod |
Country Status (8)
Country | Link |
---|---|
US (1) | US5935575A (de) |
EP (1) | EP0655927B1 (de) |
JP (2) | JP3982588B2 (de) |
AT (1) | ATE151989T1 (de) |
AU (1) | AU688736B2 (de) |
CA (1) | CA2140878C (de) |
DE (1) | DE69310182T2 (de) |
WO (1) | WO1994003202A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003202A1 (en) * | 1992-08-10 | 1994-02-17 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Interleukin-4 stimulated t lymphocyte cell death |
AU699217B2 (en) * | 1993-06-09 | 1998-11-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Interleukin-2 stimulated T lymphocyte cell death for the treatment of autoimmune diseases, allergic disorders, and graft rejection |
AU768571B2 (en) * | 1994-06-03 | 2003-12-18 | Dana-Farber Cancer Institute | Ligands for induction of antigen specific apoptosis in T cells |
US6719972B1 (en) | 1994-06-03 | 2004-04-13 | Repligen Corporation | Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies |
AU2004201139C1 (en) * | 1994-06-03 | 2008-06-12 | Dana-Faber Cancer Institute | Ligands for induction of antigen specific apoptosis in T cells |
US7041503B2 (en) | 1995-05-02 | 2006-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Modified myelin basic protein molecules |
EP0914163B1 (de) * | 1997-02-28 | 2016-02-24 | Enzo Therapeutics, Inc. | Verfahren zur selektiven Immunherabregulation (SIDR) |
WO1999051247A1 (en) * | 1998-04-03 | 1999-10-14 | Osiris Therapeutics, Inc. | Use of human mesenchymal stem cells to induce t-cell apoptosis |
US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
US20030170258A1 (en) * | 2001-05-09 | 2003-09-11 | Enzo Therapeutics, Inc. | Novel processes implementing selective immune down regulation (SIDR) |
US20050084967A1 (en) * | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
EP1539929B1 (de) * | 2002-06-28 | 2013-04-10 | Life Technologies Corporation | Verfahren zur wiederherstellung des immunrepertoirs in patienten mit immunologischen defekten in verbindung mit autoimmunität sowie transplantation von organen oder hämatopoetischen stammzellen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4904481A (en) * | 1985-04-17 | 1990-02-27 | The Board Of Trustess Of Leland Stanford University | Method of conferring immuno-tolerance to a specific antigen |
DE69018990T2 (de) * | 1989-07-14 | 1995-12-14 | Praxis Biolog Inc | Stabile interleukine enthaltende impfstoffzusammensetzungen. |
EP0563254B1 (de) * | 1990-12-19 | 1995-11-08 | Schering Corporation | Anwendung von il-4 zur steigerung der immunantwort auf immunogene in impfstoffen |
WO1994003202A1 (en) * | 1992-08-10 | 1994-02-17 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Interleukin-4 stimulated t lymphocyte cell death |
-
1993
- 1993-08-10 WO PCT/US1993/007471 patent/WO1994003202A1/en active IP Right Grant
- 1993-08-10 JP JP50560794A patent/JP3982588B2/ja not_active Expired - Fee Related
- 1993-08-10 DE DE69310182T patent/DE69310182T2/de not_active Expired - Lifetime
- 1993-08-10 AU AU48052/93A patent/AU688736B2/en not_active Ceased
- 1993-08-10 AT AT93918698T patent/ATE151989T1/de not_active IP Right Cessation
- 1993-08-10 CA CA002140878A patent/CA2140878C/en not_active Expired - Fee Related
- 1993-08-10 EP EP93918698A patent/EP0655927B1/de not_active Expired - Lifetime
-
1994
- 1994-11-30 US US08/348,286 patent/US5935575A/en not_active Expired - Fee Related
-
2006
- 2006-11-09 JP JP2006303894A patent/JP2007077164A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2140878C (en) | 2007-12-04 |
DE69310182T2 (de) | 1997-12-04 |
JP3982588B2 (ja) | 2007-09-26 |
AU4805293A (en) | 1994-03-03 |
JPH07509724A (ja) | 1995-10-26 |
CA2140878A1 (en) | 1994-02-17 |
US5935575A (en) | 1999-08-10 |
JP2007077164A (ja) | 2007-03-29 |
WO1994003202A1 (en) | 1994-02-17 |
AU688736B2 (en) | 1998-03-19 |
EP0655927B1 (de) | 1997-04-23 |
EP0655927A1 (de) | 1995-06-07 |
ATE151989T1 (de) | 1997-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |