DE69229972D1 - Temperature activated device with controlled release - Google Patents

Temperature activated device with controlled release

Info

Publication number
DE69229972D1
DE69229972D1 DE69229972T DE69229972T DE69229972D1 DE 69229972 D1 DE69229972 D1 DE 69229972D1 DE 69229972 T DE69229972 T DE 69229972T DE 69229972 T DE69229972 T DE 69229972T DE 69229972 D1 DE69229972 D1 DE 69229972D1
Authority
DE
Germany
Prior art keywords
controlled release
activated device
temperature activated
polymer
glass transition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69229972T
Other languages
German (de)
Other versions
DE69229972T2 (en
Inventor
Agis Kydonieus
Kishore R Shah
Stefanie C Decker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Convatec Technologies Inc
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE69229972D1 publication Critical patent/DE69229972D1/en
Publication of DE69229972T2 publication Critical patent/DE69229972T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Control Of Amplification And Gain Control (AREA)
  • Control Of Temperature (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Paints Or Removers (AREA)

Abstract

A polymeric device for the controlled release of active agents contained in the device in which the polymer has a glass transition temperature greater than the normal storage or non use temperature of the device. When heated to or above the glass transition temperature of the polymer, the active agent is released. The release of active agent can be switched on or off by the adjustment of the temperature of the polymeric device above or below the glass transition temperature of the polymer.
DE69229972T 1991-02-01 1992-01-31 Temperature activated device with controlled release Expired - Fee Related DE69229972T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64938191A 1991-02-01 1991-02-01

Publications (2)

Publication Number Publication Date
DE69229972D1 true DE69229972D1 (en) 1999-10-21
DE69229972T2 DE69229972T2 (en) 2000-04-27

Family

ID=24604540

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69229972T Expired - Fee Related DE69229972T2 (en) 1991-02-01 1992-01-31 Temperature activated device with controlled release

Country Status (5)

Country Link
EP (1) EP0497626B1 (en)
JP (1) JPH0542226A (en)
AT (1) ATE184481T1 (en)
CA (1) CA2060113A1 (en)
DE (1) DE69229972T2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
DE10001096A1 (en) * 2000-01-13 2001-07-26 Lohmann Therapie Syst Lts Transdermal therapeutic system for prolonged release of drugs, e.g. steroid hormones, including reservoir providing slow release of perfume to improve patient compliance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830855A (en) * 1987-11-13 1989-05-16 Landec Labs, Inc. Temperature-controlled active agent dispenser
US4840796A (en) * 1988-04-22 1989-06-20 Dow Corning Corporation Block copolymer matrix for transdermal drug release
US4908208A (en) * 1988-04-22 1990-03-13 Dow Corning Corporation Matrix for release of active ingredients
US4951657A (en) * 1988-04-22 1990-08-28 Dow Corning Corporation Heat sealable membrane for transdermal drug release

Also Published As

Publication number Publication date
EP0497626A1 (en) 1992-08-05
DE69229972T2 (en) 2000-04-27
JPH0542226A (en) 1993-02-23
EP0497626B1 (en) 1999-09-15
ATE184481T1 (en) 1999-10-15
CA2060113A1 (en) 1992-08-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CONVATEC,INC. (N. D. GES. D. STAATES DELAWARE), US

8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: CONVATEC TECHNOLOGIES INC., LAS VEGAS, NEV., US