DE69226961T2 - Verwendung von 5-ht4 - antagonisten zur herstellung eines arzneimittels zur behandlung von harninkontinenz - Google Patents

Verwendung von 5-ht4 - antagonisten zur herstellung eines arzneimittels zur behandlung von harninkontinenz

Info

Publication number
DE69226961T2
DE69226961T2 DE69226961T DE69226961T DE69226961T2 DE 69226961 T2 DE69226961 T2 DE 69226961T2 DE 69226961 T DE69226961 T DE 69226961T DE 69226961 T DE69226961 T DE 69226961T DE 69226961 T2 DE69226961 T2 DE 69226961T2
Authority
DE
Germany
Prior art keywords
treatment
antagonists
production
medicinal product
urine incontinence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69226961T
Other languages
English (en)
Other versions
DE69226961D1 (de
Inventor
Gareth John Smithkline Sanger
Kay Alison Smithkline B Wardle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919127184A external-priority patent/GB9127184D0/en
Priority claimed from GB919127185A external-priority patent/GB9127185D0/en
Priority claimed from GB929219354A external-priority patent/GB9219354D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE69226961D1 publication Critical patent/DE69226961D1/de
Application granted granted Critical
Publication of DE69226961T2 publication Critical patent/DE69226961T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69226961T 1991-12-21 1992-12-21 Verwendung von 5-ht4 - antagonisten zur herstellung eines arzneimittels zur behandlung von harninkontinenz Expired - Fee Related DE69226961T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB919127184A GB9127184D0 (en) 1991-12-21 1991-12-21 Pharmaceuticals
GB919127185A GB9127185D0 (en) 1991-12-21 1991-12-21 Pharmaceuticals
GB929219354A GB9219354D0 (en) 1992-09-12 1992-09-12 Pharmaceuticals
PCT/GB1992/002376 WO1993012785A1 (en) 1991-12-21 1992-12-21 Use of 5-ht4 modulators for the manufacture of a medicament for the treatment of the bladder diseases

Publications (2)

Publication Number Publication Date
DE69226961D1 DE69226961D1 (de) 1998-10-15
DE69226961T2 true DE69226961T2 (de) 1999-04-29

Family

ID=27265978

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226961T Expired - Fee Related DE69226961T2 (de) 1991-12-21 1992-12-21 Verwendung von 5-ht4 - antagonisten zur herstellung eines arzneimittels zur behandlung von harninkontinenz

Country Status (9)

Country Link
EP (1) EP0617620B1 (de)
JP (1) JPH07502528A (de)
AT (1) ATE170747T1 (de)
AU (1) AU671430B2 (de)
CA (1) CA2126354C (de)
DE (1) DE69226961T2 (de)
DK (1) DK0617620T3 (de)
ES (1) ES2121984T3 (de)
WO (1) WO1993012785A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998409A (en) * 1992-03-12 1999-12-07 Smithkline Beecham Plc Condensed indole derivatives as 5HT4 -receptor antagonists
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
US5726187A (en) * 1992-10-16 1998-03-10 Smithkline Beecham Plc N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-HT4 receptor antagonists
WO1996038420A1 (fr) * 1995-05-31 1996-12-05 Nisshin Flour Milling Co., Ltd. Derives de l'indazole a groupe amino monocyclique
JP2003522103A (ja) * 1998-06-15 2003-07-22 セプラコア インコーポレーテッド 無呼吸、過食症およびその他の障害を治療するための光学的に純粋な（−）−ノルシスアプリドの使用
TR200003708T2 (tr) * 1998-06-15 2001-06-21 Sepracor Inc. Apne, bulimi ve başka bozuklukların tedavi edilmesi için optik açıdan saf (+)-norsisapridin kullanımı.
US6362202B1 (en) 1999-03-02 2002-03-26 Sepracor Inc. Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
TWI263496B (en) * 1999-12-10 2006-10-11 Novartis Ag Pharmaceutical combinations and their use in treating gastrointestinal disorders
EP1551394A1 (de) * 2002-08-14 2005-07-13 Janssen Pharmaceutica N.V. BEHANDLUNG VON SYMPTOMEN DER UNTEREN HARNWEGE IM ZUSAMMENHANG MIT BLASENHYPERAKTIVITûT BEI MûNNERN UND FRAUEN

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2044854A1 (en) * 1990-07-19 1992-01-20 Hong-I Chen Method for preventing or treating urinary incontinence
GB9103862D0 (en) * 1991-02-25 1991-04-10 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
CA2126354C (en) 2006-07-11
DE69226961D1 (de) 1998-10-15
DK0617620T3 (da) 1999-06-07
CA2126354A1 (en) 1993-07-08
ATE170747T1 (de) 1998-09-15
ES2121984T3 (es) 1998-12-16
AU3168393A (en) 1993-07-28
WO1993012785A1 (en) 1993-07-08
EP0617620B1 (de) 1998-09-09
EP0617620A1 (de) 1994-10-05
JPH07502528A (ja) 1995-03-16
AU671430B2 (en) 1996-08-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee