DE69215983D1 - Method for measuring the concentration of an immunoreactant using electrochemiluminescence - Google Patents
Method for measuring the concentration of an immunoreactant using electrochemiluminescenceInfo
- Publication number
- DE69215983D1 DE69215983D1 DE69215983T DE69215983T DE69215983D1 DE 69215983 D1 DE69215983 D1 DE 69215983D1 DE 69215983 T DE69215983 T DE 69215983T DE 69215983 T DE69215983 T DE 69215983T DE 69215983 D1 DE69215983 D1 DE 69215983D1
- Authority
- DE
- Germany
- Prior art keywords
- immunoreactant
- electrochemiluminescence
- concentration
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Plasma & Fusion (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19580791A JPH0518970A (en) | 1991-07-10 | 1991-07-10 | Antigen/antibody measuring method utilizing chemiluminescence |
JP19580891A JPH0518971A (en) | 1991-07-10 | 1991-07-10 | Antigen/antibody measuring method utilizing chemiluminescence |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69215983D1 true DE69215983D1 (en) | 1997-01-30 |
DE69215983T2 DE69215983T2 (en) | 1997-05-22 |
Family
ID=26509364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1992615983 Expired - Fee Related DE69215983T2 (en) | 1991-07-10 | 1992-03-11 | Method for measuring the concentration of an immunoreactant using electrochemiluminescence |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0522677B1 (en) |
DE (1) | DE69215983T2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
BR9607193B1 (en) * | 1995-03-10 | 2009-01-13 | multispecific multispecific electrochemical test. | |
US6319670B1 (en) * | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
FI970593A (en) * | 1997-02-12 | 1998-08-13 | Sakari Mikael Kulmala | Use of coated conductors for analytical purposes |
GB9809160D0 (en) * | 1998-04-29 | 1998-07-01 | Queen Mary & Westfield College | Assay |
US7186568B1 (en) * | 2000-06-26 | 2007-03-06 | Lumigen Inc. | Electrochemiluminescence from acridan compounds |
EP1322670B1 (en) * | 2000-06-26 | 2005-12-21 | Lumigen, Inc. | Electrochemiluminescence from acridan compounds |
US6703210B2 (en) * | 2000-11-02 | 2004-03-09 | Satake Corporation | Method and device for determining concentration of dioxins |
DE60236732D1 (en) * | 2001-07-30 | 2010-07-29 | Meso Scale Technologies Llc | ASSAY ELECTRODES WITH REAL-ESTABLISHED LIPID / PROTEIN LAYERS AND PROCESS FOR THEIR PREPARATION AND USE |
CN101038255B (en) * | 2007-04-06 | 2010-05-19 | 福州大学 | Capillary electrophoresis chemiluminescence detector of acridiniumester, acridine sulfonamide and marker thereof, and method thereof |
WO2012028167A2 (en) * | 2010-05-20 | 2012-03-08 | Innohyphen Bv | Acridinium ester chemiluminescence upon reductive triggering |
JP6010110B2 (en) | 2011-04-20 | 2016-10-19 | アクセス メディカル システムズ,リミティド | Repeated amplification of light-emitting polymers. |
CN105717098B (en) * | 2016-02-25 | 2018-03-27 | 济南大学 | A kind of preparation method and application of the electrogenerated chemiluminescence bisphenol-A biology sensor based on nitrogen-doped titanium dioxide nanometer sheet |
CN106248658B (en) * | 2016-09-08 | 2018-11-13 | 济南大学 | The preparation of paper substrate electrochemical luminescence converter and the application in carcinomebryonic antigen detection |
CN109696461B (en) * | 2017-10-24 | 2023-05-26 | 上海药明生物技术有限公司 | Release detection method of therapeutic antibody |
WO2019079970A1 (en) * | 2017-10-24 | 2019-05-02 | 上海药明生物技术有限公司 | Release detection method for therapeutic antibody |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3352791A (en) * | 1965-01-22 | 1967-11-14 | American Cyanamid Co | Generation of light by the reaction of peroxide with heterocyclic derivatives |
FR2043486B1 (en) * | 1969-05-28 | 1973-07-13 | Roussel Uclaf | |
GB1461877A (en) * | 1974-02-12 | 1977-01-19 | Wellcome Found | Assay method utilizing chemiluminescence |
EP0082636B2 (en) * | 1981-12-11 | 2006-10-18 | The Welsh National School of Medicine | Luminescent labelling materials and procedures |
ATE111083T1 (en) * | 1986-10-22 | 1994-09-15 | Abbott Lab | CHEMILUMINESCENT ACRIDINIUM AND PHENANTRIDINIUM SALTS. |
DE3844954C2 (en) * | 1988-02-20 | 1998-07-16 | Hoechst Ag | Special chemiluminescent acridine derivatives and their use in luminescent immunoassays |
CA1325527C (en) * | 1988-04-28 | 1993-12-28 | Nicholas Leventis | Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena |
CA1339491C (en) * | 1988-09-26 | 1997-10-07 | Say-Jong Law | Nucleophilic polysubstituted aryl acridinium ester and uses thereof |
US5068088A (en) * | 1988-11-03 | 1991-11-26 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
GB2233450B (en) * | 1989-06-24 | 1993-06-30 | Univ Wales Medicine | Detecting or quantifing multiple analytes with luminescent reagents |
-
1992
- 1992-03-11 EP EP19920302080 patent/EP0522677B1/en not_active Expired - Lifetime
- 1992-03-11 DE DE1992615983 patent/DE69215983T2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0522677A1 (en) | 1993-01-13 |
EP0522677B1 (en) | 1996-12-18 |
DE69215983T2 (en) | 1997-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8320 | Willingness to grant licences declared (paragraph 23) | ||
8339 | Ceased/non-payment of the annual fee |