DE69210078D1 - Umlagerungsverbindungen von Taxol und deren Verwendung bei der Bestimmung von in vivo-Aktivitäten - Google Patents

Umlagerungsverbindungen von Taxol und deren Verwendung bei der Bestimmung von in vivo-Aktivitäten

Info

Publication number
DE69210078D1
DE69210078D1 DE69210078T DE69210078T DE69210078D1 DE 69210078 D1 DE69210078 D1 DE 69210078D1 DE 69210078 T DE69210078 T DE 69210078T DE 69210078 T DE69210078 T DE 69210078T DE 69210078 D1 DE69210078 D1 DE 69210078D1
Authority
DE
Germany
Prior art keywords
taxol
ring
preferred
compounds
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69210078T
Other languages
German (de)
English (en)
Inventor
David G I Kingston
Gamini Samaranyake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Tech Intellectual Properties Inc
Original Assignee
Virginia Tech Intellectual Properties Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Tech Intellectual Properties Inc filed Critical Virginia Tech Intellectual Properties Inc
Application granted granted Critical
Publication of DE69210078D1 publication Critical patent/DE69210078D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69210078T 1991-03-18 1992-02-27 Umlagerungsverbindungen von Taxol und deren Verwendung bei der Bestimmung von in vivo-Aktivitäten Expired - Lifetime DE69210078D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67043291A 1991-03-18 1991-03-18

Publications (1)

Publication Number Publication Date
DE69210078D1 true DE69210078D1 (de) 1996-05-30

Family

ID=24690379

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69210078T Expired - Lifetime DE69210078D1 (de) 1991-03-18 1992-02-27 Umlagerungsverbindungen von Taxol und deren Verwendung bei der Bestimmung von in vivo-Aktivitäten

Country Status (5)

Country Link
EP (1) EP0505047B1 (cg-RX-API-DMAC10.html)
JP (1) JPH0684364B2 (cg-RX-API-DMAC10.html)
AT (1) ATE137229T1 (cg-RX-API-DMAC10.html)
DE (1) DE69210078D1 (cg-RX-API-DMAC10.html)
TW (1) TW223634B (cg-RX-API-DMAC10.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ258044A (en) * 1992-11-27 1995-12-21 Faulding F H & Co Ltd Pharmaceutical composition comprising taxol, solubilising agent, an acid and an organic solvent
DK0835657T3 (da) 1992-11-27 2005-01-10 Mayne Pharma Usa Inc Stabil, injicerbar paclitaxelsammensætning
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
GB9705903D0 (en) 1997-03-21 1997-05-07 Elliott Gillian D VP22 Proteins and uses thereof
EP1318794A2 (en) 2000-09-22 2003-06-18 Bristol-Myers Squibb Company Method for reducing toxicity of combined chemotherapies
US6919370B2 (en) 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
JP7025412B2 (ja) 2016-09-06 2022-02-24 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ パクリタキセル－アルブミン－結合剤組成物並びに該組成物の使用及び製造方法

Also Published As

Publication number Publication date
ATE137229T1 (de) 1996-05-15
EP0505047B1 (en) 1996-04-24
TW223634B (cg-RX-API-DMAC10.html) 1994-05-11
EP0505047A1 (en) 1992-09-23
JPH0578342A (ja) 1993-03-30
JPH0684364B2 (ja) 1994-10-26

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Legal Events

Date Code Title Description
8332 No legal effect for de