DE69130377D1 - Herstellung und Isolierung von O-Glykanen - Google Patents

Herstellung und Isolierung von O-Glykanen

Info

Publication number
DE69130377D1
DE69130377D1 DE69130377T DE69130377T DE69130377D1 DE 69130377 D1 DE69130377 D1 DE 69130377D1 DE 69130377 T DE69130377 T DE 69130377T DE 69130377 T DE69130377 T DE 69130377T DE 69130377 D1 DE69130377 D1 DE 69130377D1
Authority
DE
Germany
Prior art keywords
glycans
isolation
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69130377T
Other languages
English (en)
Other versions
DE69130377T2 (de
Inventor
Rajesh Bhikhu Parekh
Anthony Hugh Merry
James Bruce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ProZyme Inc
Original Assignee
Oxford GlycoSystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford GlycoSystems Ltd filed Critical Oxford GlycoSystems Ltd
Application granted granted Critical
Publication of DE69130377D1 publication Critical patent/DE69130377D1/de
Publication of DE69130377T2 publication Critical patent/DE69130377T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8881—Modular construction, specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00376—Conductive heating, e.g. heated plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00415—Other radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6043—Construction of the column joining multiple columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00712—Automatic status testing, e.g. at start-up or periodic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69130377T 1990-06-21 1991-06-18 Herstellung und Isolierung von O-Glykanen Expired - Lifetime DE69130377T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909013830A GB9013830D0 (en) 1990-06-21 1990-06-21 Release and isolation of unreduced'o-linked type'oligosaccharides

Publications (2)

Publication Number Publication Date
DE69130377D1 true DE69130377D1 (de) 1998-11-26
DE69130377T2 DE69130377T2 (de) 1999-03-11

Family

ID=10677969

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130377T Expired - Lifetime DE69130377T2 (de) 1990-06-21 1991-06-18 Herstellung und Isolierung von O-Glykanen

Country Status (5)

Country Link
US (1) US6180779B1 (de)
EP (1) EP0462798B1 (de)
JP (1) JPH0687905A (de)
DE (1) DE69130377T2 (de)
GB (1) GB9013830D0 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462794B1 (de) * 1990-06-21 1998-09-09 Oxford GlycoSciences (UK) Limited Automatisiertes Verfahren zur Spaltung von Biomolekülen
EP0462795A3 (en) * 1990-06-21 1993-02-24 Oxford Glycosystems Limited Isolation of glycans
GB9013828D0 (en) * 1990-06-21 1990-08-15 Oxford Glycosystems Ltd Release and isolation of unreduced'n-and o-linked type'oligosaccharides
GB9013831D0 (en) * 1990-06-21 1990-08-15 Oxford Glycosystems Ltd Release and isolation of unreduced'n-linked type'oligosaccharides
WO1995015969A1 (en) * 1993-12-09 1995-06-15 Macquarie University Glycozylhydrazines, preparation, immobilization and reactions of: glycoprotein analysis and o-glycan removal
US6905076B2 (en) * 2002-11-15 2005-06-14 Advanced Research And Technology Institute, Inc. High temperature incubation system and method for small volumes
US20040096948A1 (en) * 2002-11-15 2004-05-20 Yunping Huang Glycoprotein cleavage protocol for oligosaccharide analysis
EP1976857A4 (de) * 2006-01-13 2011-08-03 Baxter Int Verfahren zur reinigung von polysacchariden
US8795746B2 (en) 2011-02-16 2014-08-05 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic use of mucin glycans
CN104024849A (zh) 2011-08-12 2014-09-03 生命科技公司 用于高通量聚糖分析的装置、方法、计算机程序产品和试剂盒

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347163A1 (de) * 1983-12-27 1985-07-04 Behringwerke Ag, 3550 Marburg Verwendung von oligosacchariden zur chemotherapie oder chemoprophylaxe der malaria
US4719294A (en) * 1985-09-06 1988-01-12 Monsanto Company Isolation of unreduced oligosaccharides
EP0462795A3 (en) * 1990-06-21 1993-02-24 Oxford Glycosystems Limited Isolation of glycans
GB9013828D0 (en) * 1990-06-21 1990-08-15 Oxford Glycosystems Ltd Release and isolation of unreduced'n-and o-linked type'oligosaccharides
GB9013831D0 (en) * 1990-06-21 1990-08-15 Oxford Glycosystems Ltd Release and isolation of unreduced'n-linked type'oligosaccharides

Also Published As

Publication number Publication date
DE69130377T2 (de) 1999-03-11
GB9013830D0 (en) 1990-08-15
EP0462798A2 (de) 1991-12-27
EP0462798B1 (de) 1998-10-21
US6180779B1 (en) 2001-01-30
EP0462798A3 (en) 1993-03-10
JPH0687905A (ja) 1994-03-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PROZYME, INC., SAN LEANDRO, CALIF., US

8328 Change in the person/name/address of the agent

Representative=s name: LEINWEBER & ZIMMERMANN, 80331 MUENCHEN