DE69024159D1 - 3-aroyl-2-oxindole-1-carboxamides - Google Patents

3-aroyl-2-oxindole-1-carboxamides

Info

Publication number
DE69024159D1
DE69024159D1 DE69024159T DE69024159T DE69024159D1 DE 69024159 D1 DE69024159 D1 DE 69024159D1 DE 69024159 T DE69024159 T DE 69024159T DE 69024159 T DE69024159 T DE 69024159T DE 69024159 D1 DE69024159 D1 DE 69024159D1
Authority
DE
Germany
Prior art keywords
oxindole
carboxamides
aroyl
iodoaroyl
deiodination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69024159T
Other languages
German (de)
Other versions
DE69024159T2 (en
Inventor
Gary Richard Schulte
Frederick Jacob Ehrgott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE69024159D1 publication Critical patent/DE69024159D1/en
Application granted granted Critical
Publication of DE69024159T2 publication Critical patent/DE69024159T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

Process for making antiinflammatory 3-aroyl-2-oxindole-1-carboxamides by reductive debromination or deiodination of 3-(bromo- or iodoaroyl)-2-oxindole-1-carboxamides.
DE69024159T 1989-10-06 1990-10-03 3-aroyl-2-oxindole-1-carboxamides Expired - Fee Related DE69024159T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/417,988 US5059693A (en) 1989-10-06 1989-10-06 Process for making 3-aroyl-2-oxindole-1-carboxamides

Publications (2)

Publication Number Publication Date
DE69024159D1 true DE69024159D1 (en) 1996-01-25
DE69024159T2 DE69024159T2 (en) 1996-05-09

Family

ID=23656197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024159T Expired - Fee Related DE69024159T2 (en) 1989-10-06 1990-10-03 3-aroyl-2-oxindole-1-carboxamides

Country Status (20)

Country Link
US (1) US5059693A (en)
EP (1) EP0421749B1 (en)
JP (1) JPH0710860B2 (en)
KR (1) KR920010072B1 (en)
AT (1) ATE131476T1 (en)
AU (1) AU621511B2 (en)
CA (1) CA2026974C (en)
DE (1) DE69024159T2 (en)
DK (1) DK0421749T3 (en)
ES (1) ES2080811T3 (en)
FI (1) FI102537B (en)
GR (1) GR3018680T3 (en)
HU (1) HU215841B (en)
IE (1) IE68666B1 (en)
IL (1) IL95831A (en)
MY (1) MY106583A (en)
NO (1) NO176607C (en)
NZ (1) NZ235565A (en)
PT (1) PT95518B (en)
ZA (1) ZA907974B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK590689A3 (en) * 1988-10-18 1996-03-06 Pfizer 3-aryl-2-oxindole-1-carboxamides and method of their preparation
HUP9600855A3 (en) * 1996-04-03 1998-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing tenidap
AU3595000A (en) * 1999-02-11 2000-08-29 Ingersoll-Rand Company Automatically regulated heating system for paving screed
KR101677919B1 (en) * 2015-05-07 2016-11-21 한서대학교 산학협력단 Portable wireless speaker device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039591A (en) * 1975-03-20 1977-08-02 Scm Corporation Synthesis of dehydrophytol and Vitamin E
US4474967A (en) * 1983-04-27 1984-10-02 Pfizer Inc. 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
IN162090B (en) * 1984-03-19 1988-03-26 Pfizer
DE3510033A1 (en) * 1985-03-20 1986-09-25 Basf Ag METHOD FOR REDUCING DEHALOGENATION OF HALOGEN COMPOUNDS
RO105052B1 (en) * 1987-02-02 1994-12-01 Pfizer Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
SK590689A3 (en) * 1988-10-18 1996-03-06 Pfizer 3-aryl-2-oxindole-1-carboxamides and method of their preparation

Also Published As

Publication number Publication date
FI904909A0 (en) 1990-10-05
FI102537B1 (en) 1998-12-31
JPH0710860B2 (en) 1995-02-08
HU215841B (en) 1999-09-28
IE68666B1 (en) 1996-07-10
IE903565A1 (en) 1991-04-10
GR3018680T3 (en) 1996-04-30
IL95831A0 (en) 1991-06-30
NO904334D0 (en) 1990-10-05
MY106583A (en) 1995-06-30
JPH03151380A (en) 1991-06-27
EP0421749B1 (en) 1995-12-13
PT95518B (en) 1997-07-31
AU621511B2 (en) 1992-03-12
ES2080811T3 (en) 1996-02-16
CA2026974A1 (en) 1991-04-07
DE69024159T2 (en) 1996-05-09
CA2026974C (en) 1999-12-21
AU6385690A (en) 1991-06-20
EP0421749A2 (en) 1991-04-10
HU906357D0 (en) 1991-04-29
FI102537B (en) 1998-12-31
NZ235565A (en) 1992-02-25
EP0421749A3 (en) 1992-01-08
ZA907974B (en) 1992-05-27
NO904334L (en) 1991-04-08
PT95518A (en) 1991-08-14
NO176607B (en) 1995-01-23
ATE131476T1 (en) 1995-12-15
DK0421749T3 (en) 1996-01-22
KR910007920A (en) 1991-05-30
IL95831A (en) 1995-01-24
HUT59133A (en) 1992-04-28
KR920010072B1 (en) 1992-11-13
NO176607C (en) 1995-05-03
US5059693A (en) 1991-10-22

Similar Documents

Publication Publication Date Title
GB2087880B (en) 7-oxo-4-thia-1-azabicyclo(3,2,0)-heptane and 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives
OA06914A (en) Process for the preparation of substituted iminodiacides.
NO2004007I2 (en) Nebivolol hydrochloride is the generic compound of the following racemic mixture: (+) Δ (SRRR) + (RSSS) , which has the following structure:
BR9106518A (en) PREPARATION OF REPLACED PIPERIDINES
NO894410D0 (en) PROCEDURE FOR THE PREPARATION OF 3,5-DIMETHYL-4-METOXYPYRIDINE DERIVATIVES AND NEW INTERMEDIATES FOR THIS PURPOSE.
DE69033069D1 (en) Prostaglandin analogs
BE862106A (en) PROCESS FOR THE PREPARATION OF MELTED ELECTRO-CORUNDUM
ES2086065T3 (en) PREPARATION OF SUBSTITUTED TETRAHIDROPIRIDINAS.
LU80402A1 (en) PROCESS FOR THE PRODUCTION OF 2,6-DIAMINONEBULARINS
ES2080811T3 (en) 3-AROIL-2-OXINDOL-1-CARBOXAMIDES.
BE868797A (en) PROCESS FOR SEPARATION OF 3- (3,4-DIBENZYLOXYPHENYL) DIASTEREOISOMERIC SERINE
HUT54976A (en) Process for producing propaneamine derivatives
ATE312193T1 (en) MICROBIOLOGICAL PRODUCTION OF L-ASCORBIC ACID
BE865429A (en) PROCESS FOR THE PRODUCTION OF ALKANE POLYOLS
ES2089176T3 (en) PROCEDURE FOR THE PREPARATION OF FLUOROMETIL-SUBSTITUTED PIPERIDINE CARBODITIOATES.
ES2082890T3 (en) PROCEDURE FOR THE PREPARATION OF FORSKOLINA DERIVATIVES 6- (AMINOPROPIONYL SUBSTITUTED).
BE884206A (en) PROCESS FOR THE PREPARATION OF 3- (4) -FORMYL-TRICYCLO- (5,2,1,02,6) -DECENE-8
ES2048213T3 (en) PROCEDURE FOR THE PREPARATION OF ACID ANHYDRIDES.
RO78476A (en) PROCESS FOR THE PREPARATION OF 3'-PHENYL-SPIRO (ISOBENZOFURAN-1 (3H), 5 '(4'H) -ISOXAZOLE) -3-ONE
ES2080286T3 (en) PROCEDURE FOR THE PREPARATION OF PIRIDINADICARBOXILATOS SUBSTITUTED WITH FLUOROMETILO.
RO79790A2 (en) PROCESS FOR OBTAINING WHITE MICROALLY WHITE
IT7851816A0 (en) BENZOXAZOLIL-PHENYLSTILBENES PROCEDURE FOR THEIR PRODUCTION AS WELL AS THEIR APPLICATION AS OPTICAL WHITENERS
PT68385A (en) PROCESS FOR PRODUCING ASBESTOS DIAPHRAGM
DK93884A (en) PROCEDURE FOR THE MANUFACTURING OF 1,5-DEBATED-1,5,10-TRIAZADECANES, INTERMEDIATES THEREOF, AND THEIR PREPARATION
FI873000A (en) Substituted 1,2,3-thiadiazole-4-thiolates

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee