DE69017594D1 - Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel. - Google Patents

Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel.

Info

Publication number
DE69017594D1
DE69017594D1 DE69017594T DE69017594T DE69017594D1 DE 69017594 D1 DE69017594 D1 DE 69017594D1 DE 69017594 T DE69017594 T DE 69017594T DE 69017594 T DE69017594 T DE 69017594T DE 69017594 D1 DE69017594 D1 DE 69017594D1
Authority
DE
Germany
Prior art keywords
thio
reverse transcriptase
compound
product
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69017594T
Other languages
English (en)
Inventor
Herbert Blough
Miria Richetti
Henri Buc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BLOUGH HERBERT A DR BERWYN PA US
Original Assignee
BLOUGH HERBERT A DR BERWYN PA US
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BLOUGH HERBERT A DR BERWYN PA US filed Critical BLOUGH HERBERT A DR BERWYN PA US
Application granted granted Critical
Publication of DE69017594D1 publication Critical patent/DE69017594D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/08Deoxysugars; Unsaturated sugars; Osones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69017594T 1989-06-02 1990-06-01 Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel. Expired - Lifetime DE69017594D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8907356A FR2647792B1 (de) 1989-06-02 1989-06-02
PCT/FR1990/000387 WO1990014825A1 (fr) 1989-06-02 1990-06-01 Produit inhibiteur specifique de la transcriptase inverse de retrovirus, et son application comme medicament

Publications (1)

Publication Number Publication Date
DE69017594D1 true DE69017594D1 (de) 1995-04-13

Family

ID=9382333

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69017594T Expired - Lifetime DE69017594D1 (de) 1989-06-02 1990-06-01 Spezifischer produktinhibitor der retroviralen reversen transkriptase und seine verwendung als arzneimittel.

Country Status (6)

Country Link
EP (1) EP0427843B1 (de)
JP (1) JPH04501427A (de)
AT (1) ATE119392T1 (de)
DE (1) DE69017594D1 (de)
FR (1) FR2647792B1 (de)
WO (1) WO1990014825A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177435B1 (en) 1992-05-13 2001-01-23 Glaxo Wellcome Inc. Therapeutic combinations
US5603963A (en) * 1994-07-28 1997-02-18 University Of Cincinnati Method for the treatment of retroviral diseases such as acquired immune deficiency syndrome utilizing (pseudo)halogen complexes of gold(1)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315001A (en) * 1979-08-17 1982-02-09 Blough Herbert A 2-Deoxy glucose as an antiviral agent against herpes simplex
US4657763A (en) * 1985-09-03 1987-04-14 Michael Ebert Combined chrysotherapeutic agents for autoimmune diseases

Also Published As

Publication number Publication date
JPH04501427A (ja) 1992-03-12
EP0427843B1 (de) 1995-03-08
EP0427843A1 (de) 1991-05-22
ATE119392T1 (de) 1995-03-15
WO1990014825A1 (fr) 1990-12-13
FR2647792B1 (de) 1995-06-23
FR2647792A1 (de) 1990-12-07

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Legal Events

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