DE69016494D1 - Peptide with activity against metastases. - Google Patents

Peptide with activity against metastases.

Info

Publication number
DE69016494D1
DE69016494D1 DE69016494T DE69016494T DE69016494D1 DE 69016494 D1 DE69016494 D1 DE 69016494D1 DE 69016494 T DE69016494 T DE 69016494T DE 69016494 T DE69016494 T DE 69016494T DE 69016494 D1 DE69016494 D1 DE 69016494D1
Authority
DE
Germany
Prior art keywords
peptide
activity against
against metastases
metastases
pentapeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016494T
Other languages
German (de)
Other versions
DE69016494T2 (en
Inventor
Charles Steven Schasteen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DE69016494D1 publication Critical patent/DE69016494D1/en
Application granted granted Critical
Publication of DE69016494T2 publication Critical patent/DE69016494T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention discloses an acylated pentapeptide that exhibits inhibitory activity toward malignant cell metastasis.
DE69016494T 1989-05-10 1990-05-09 Peptide with activity against metastases. Expired - Fee Related DE69016494T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/350,066 US5039662A (en) 1989-05-10 1989-05-10 Peptide with anti-metastasis activity

Publications (2)

Publication Number Publication Date
DE69016494D1 true DE69016494D1 (en) 1995-03-16
DE69016494T2 DE69016494T2 (en) 1995-09-14

Family

ID=23375090

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016494T Expired - Fee Related DE69016494T2 (en) 1989-05-10 1990-05-09 Peptide with activity against metastases.

Country Status (8)

Country Link
US (1) US5039662A (en)
EP (1) EP0397635B1 (en)
JP (1) JPH032196A (en)
AT (1) ATE118016T1 (en)
DE (1) DE69016494T2 (en)
DK (1) DK0397635T3 (en)
ES (1) ES2036513T1 (en)
GR (1) GR3015239T3 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759515A (en) * 1989-08-09 1998-06-02 Rhomed Incorporated Polyvalent peptide pharmaceutical applications
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
US5410024A (en) * 1993-01-21 1995-04-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide amides
US20030199531A1 (en) * 2001-07-19 2003-10-23 Todd Wipke YIGSR peptidomimetics and methods for using the same
EP1741719B1 (en) * 2004-03-31 2015-02-25 Patent Technology Development Inc. Epithelial cell growth promoter
JP2013537172A (en) 2010-09-09 2013-09-30 トリフォイリウム エーピーエス Respiratory administration of angiogenesis inhibitors
KR101644982B1 (en) * 2015-07-23 2016-08-02 주식회사 엔솔바이오사이언스 A novel peptide and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8802441A1 (en) * 1985-06-03 1988-06-16 Meloy Lab Laminin and the production thereof.
IL85372A (en) * 1987-02-12 1992-12-01 Us Health Penta to nona-peptides with laminin - like activity having an amino acid sequence and anti- metastatic compositions containing them
US5066716A (en) * 1988-12-13 1991-11-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides

Also Published As

Publication number Publication date
ES2036513T1 (en) 1993-06-01
EP0397635A1 (en) 1990-11-14
JPH032196A (en) 1991-01-08
DK0397635T3 (en) 1995-04-03
US5039662A (en) 1991-08-13
EP0397635B1 (en) 1995-02-01
GR3015239T3 (en) 1995-06-30
DE69016494T2 (en) 1995-09-14
ATE118016T1 (en) 1995-02-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee