DE69007964T2 - Verwendung von Thrombospondin zur Beschleunigung der Wundheilung. - Google Patents

Verwendung von Thrombospondin zur Beschleunigung der Wundheilung.

Info

Publication number
DE69007964T2
DE69007964T2 DE69007964T DE69007964T DE69007964T2 DE 69007964 T2 DE69007964 T2 DE 69007964T2 DE 69007964 T DE69007964 T DE 69007964T DE 69007964 T DE69007964 T DE 69007964T DE 69007964 T2 DE69007964 T2 DE 69007964T2
Authority
DE
Germany
Prior art keywords
thrombospondin
wound healing
accelerate wound
pharmaceutical compositions
accelerate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69007964T
Other languages
English (en)
Other versions
DE69007964D1 (de
Inventor
Jacob Eyal
George Paul Tuszynski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PENNSYLVANIA MED COLLEGE
WR Grace and Co Conn
WR Grace and Co
Original Assignee
PENNSYLVANIA MED COLLEGE
WR Grace and Co Conn
WR Grace and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PENNSYLVANIA MED COLLEGE, WR Grace and Co Conn, WR Grace and Co filed Critical PENNSYLVANIA MED COLLEGE
Application granted granted Critical
Publication of DE69007964D1 publication Critical patent/DE69007964D1/de
Publication of DE69007964T2 publication Critical patent/DE69007964T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
DE69007964T 1990-02-22 1990-12-21 Verwendung von Thrombospondin zur Beschleunigung der Wundheilung. Expired - Fee Related DE69007964T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/483,500 US5155038A (en) 1990-02-22 1990-02-22 Use of thrombospondin to promote wound healing

Publications (2)

Publication Number Publication Date
DE69007964D1 DE69007964D1 (de) 1994-05-11
DE69007964T2 true DE69007964T2 (de) 1994-09-22

Family

ID=23920296

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69007964T Expired - Fee Related DE69007964T2 (de) 1990-02-22 1990-12-21 Verwendung von Thrombospondin zur Beschleunigung der Wundheilung.

Country Status (8)

Country Link
US (1) US5155038A (de)
EP (1) EP0443224B1 (de)
JP (1) JPH04211019A (de)
AT (1) ATE103815T1 (de)
CA (1) CA2031817C (de)
DE (1) DE69007964T2 (de)
DK (1) DK0443224T3 (de)
ES (1) ES2063250T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192744A (en) * 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5468505A (en) * 1992-02-28 1995-11-21 Board Of Regents, The University Of Texas System Local delivery of fibrinolysis enhancing agents
US5399667A (en) * 1993-03-05 1995-03-21 Washington University Thrombospondin receptor binding peptides
US5627265A (en) * 1993-03-05 1997-05-06 Washington University Receptor for cell-binding domain of thrombospondins
US5641483A (en) * 1995-06-07 1997-06-24 Beaulieu; Andre Wound healing formulations containing human plasma fibronectin
US5877149A (en) 1995-06-07 1999-03-02 Beaulieu; Andre Deepithelialized skin diffusion cell system
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US5733884A (en) 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
CN1069213C (zh) * 1995-12-08 2001-08-08 上海贝特生物技术有限公司 造血前体细胞保护剂
US6461640B1 (en) 1995-12-08 2002-10-08 Board Of Regents, The University Of Texas System Local delivery of fibrinolysis enhancing agents
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6716963B1 (en) * 1998-05-22 2004-04-06 Abbott Laboratories Peptide antiangiogenic drugs
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6380161B1 (en) 1999-06-21 2002-04-30 Inkine Pharmaceutical Company, Inc. Compositions for treating chemotherapy-resistant tumor cells and targeted chemotherapy compositions
WO2001090179A2 (en) * 2000-05-23 2001-11-29 Lexicon Genetics Incorporated Novel human thrombospondin-like proteins and polynucleotides encoding the same
US10821155B2 (en) * 2018-06-27 2020-11-03 Juvena Therapeutics, Inc. Heparin-associated polypeptides and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792525A (en) * 1982-08-04 1988-12-20 La Jolla Cancer Research Foundation Tetrapeptide
US4614517A (en) * 1982-08-04 1986-09-30 La Jolla Cancer Research Foundation Tetrapeptide
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide

Also Published As

Publication number Publication date
DE69007964D1 (de) 1994-05-11
ES2063250T3 (es) 1995-01-01
EP0443224A1 (de) 1991-08-28
CA2031817A1 (en) 1991-08-23
US5155038A (en) 1992-10-13
JPH04211019A (ja) 1992-08-03
EP0443224B1 (de) 1994-04-06
ATE103815T1 (de) 1994-04-15
CA2031817C (en) 2002-02-12
DK0443224T3 (da) 1994-05-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee