DE68923159D1 - Verfahren zur Herstellung von 1,4-Dihydropyridin-Derivaten. - Google Patents

Verfahren zur Herstellung von 1,4-Dihydropyridin-Derivaten.

Info

Publication number
DE68923159D1
DE68923159D1 DE68923159T DE68923159T DE68923159D1 DE 68923159 D1 DE68923159 D1 DE 68923159D1 DE 68923159 T DE68923159 T DE 68923159T DE 68923159 T DE68923159 T DE 68923159T DE 68923159 D1 DE68923159 D1 DE 68923159D1
Authority
DE
Germany
Prior art keywords
preparation
dihydropyridine derivatives
dihydropyridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68923159T
Other languages
English (en)
Other versions
DE68923159T2 (de
Inventor
Hiroaki Satoh
Shizuo Himoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Publication of DE68923159D1 publication Critical patent/DE68923159D1/de
Application granted granted Critical
Publication of DE68923159T2 publication Critical patent/DE68923159T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68923159T 1988-11-30 1989-11-29 Verfahren zur Herstellung von 1,4-Dihydropyridin-Derivaten. Expired - Fee Related DE68923159T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63301075A JPH02149563A (ja) 1988-11-30 1988-11-30 ２−ハロエトキシカルボニル基を含有する１，４−ジヒドロピリジン誘導体の製造法

Publications (2)

Publication Number Publication Date
DE68923159D1 true DE68923159D1 (de) 1995-07-27
DE68923159T2 DE68923159T2 (de) 1995-10-26

Family

ID=17892570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68923159T Expired - Fee Related DE68923159T2 (de) 1988-11-30 1989-11-29 Verfahren zur Herstellung von 1,4-Dihydropyridin-Derivaten.

Country Status (3)

Country Link
EP (1) EP0371492B1 (de)
JP (1) JPH02149563A (de)
DE (1) DE68923159T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006082A1 (en) * 1991-09-13 1993-04-01 Merck & Co., Inc. Process for the preparation of 4-substituted-1,4-dihydropyridines
US5310917A (en) * 1991-09-13 1994-05-10 Merck & Co., Inc. Process for the preparation of 4-substituted-1,4-dihydropydrines
DK0657432T3 (da) * 1993-12-10 2003-07-07 Bayer Ag Phenylsubstituerede 1,4-dihydropyridiner med cerebral aktivitet
DE19842900A1 (de) * 1998-09-18 2000-03-23 Basf Ag Verfahren zur gemeinsamen Herstellung eines cyclischen Lactams und eines cyclischen Amins
JP4544895B2 (ja) * 2004-03-31 2010-09-15 大日本印刷株式会社 ジヒドロピリジン誘導体の製造法
WO2012123966A1 (en) 2011-03-04 2012-09-20 Arch Pharmalabs Limited Process for the preparation of 4 -substituted -1, 4-dihydropyridines
CN114149360B (zh) * 2021-11-25 2024-03-01 天津太平洋化学制药有限公司 一种高纯度尼群地平原料药的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3377352D1 (en) * 1982-06-03 1988-08-18 Pierrel Spa Dihydropyridines with an antagonistic activity to calcium, process for their preparation, and pharmaceutical compositions containing them
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US4755512A (en) * 1984-04-11 1988-07-05 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities
DK114587A (da) * 1986-03-12 1987-09-13 Byk Gulden Lomberg Chem Fab Monocycliske esterderivater
EP0287828A1 (de) * 1987-03-27 1988-10-26 Byk Gulden Lomberg Chemische Fabrik GmbH Neue Zwischenprodukte und Verfahren

Also Published As

Publication number Publication date
EP0371492A3 (en) 1990-12-05
EP0371492B1 (de) 1995-06-21
EP0371492A2 (de) 1990-06-06
JPH02149563A (ja) 1990-06-08
DE68923159T2 (de) 1995-10-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NISSHIN SEIFUN GROUP INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee