DE68913997D1 - Fluorierte flavon-essigsäure. - Google Patents

Fluorierte flavon-essigsäure.

Info

Publication number
DE68913997D1
DE68913997D1 DE90901973T DE68913997T DE68913997D1 DE 68913997 D1 DE68913997 D1 DE 68913997D1 DE 90901973 T DE90901973 T DE 90901973T DE 68913997 T DE68913997 T DE 68913997T DE 68913997 D1 DE68913997 D1 DE 68913997D1
Authority
DE
Germany
Prior art keywords
acetic acid
flavon
fluorine
fluorinated
antitumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90901973T
Other languages
English (en)
Other versions
DE68913997T2 (de
Inventor
Paul Aristoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DE68913997D1 publication Critical patent/DE68913997D1/de
Publication of DE68913997T2 publication Critical patent/DE68913997T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DE68913997T 1989-01-19 1989-12-11 Fluorierte flavon-essigsäure. Expired - Fee Related DE68913997T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29910689A 1989-01-19 1989-01-19
PCT/US1989/005446 WO1990008143A1 (en) 1989-01-19 1989-12-11 Fluorinated flavone acetic acid

Publications (2)

Publication Number Publication Date
DE68913997D1 true DE68913997D1 (de) 1994-04-21
DE68913997T2 DE68913997T2 (de) 1994-07-28

Family

ID=23153335

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68913997T Expired - Fee Related DE68913997T2 (de) 1989-01-19 1989-12-11 Fluorierte flavon-essigsäure.

Country Status (9)

Country Link
EP (1) EP0454728B1 (de)
JP (1) JPH04502761A (de)
KR (1) KR910700240A (de)
AT (1) ATE102934T1 (de)
AU (1) AU4847390A (de)
CA (1) CA2006307A1 (de)
DE (1) DE68913997T2 (de)
ES (1) ES2062507T3 (de)
WO (1) WO1990008143A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USH1427H (en) * 1988-04-06 1995-04-04 Briet; Phillipe Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2
GB9707013D0 (en) * 1997-04-07 1997-05-28 Univ Strathclyde Halo and/or nitro-substituted flavonoids
AU2016226380A1 (en) * 2015-03-02 2017-09-21 Colonaryconcepts Llc Compounds and methods for PEG metabolite and PEG breakdown product assays

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2516922A1 (fr) * 1981-11-25 1983-05-27 Lipha Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant

Also Published As

Publication number Publication date
DE68913997T2 (de) 1994-07-28
ATE102934T1 (de) 1994-04-15
ES2062507T3 (es) 1994-12-16
EP0454728A1 (de) 1991-11-06
AU4847390A (en) 1990-08-13
EP0454728B1 (de) 1994-03-16
CA2006307A1 (en) 1990-07-19
KR910700240A (ko) 1991-03-14
JPH04502761A (ja) 1992-05-21
WO1990008143A1 (en) 1990-07-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee