DE68912476D1 - Substituierte Thienopyrane als blutdrucksenkendes Mittel. - Google Patents

Substituierte Thienopyrane als blutdrucksenkendes Mittel.

Info

Publication number
DE68912476D1
DE68912476D1 DE89309685T DE68912476T DE68912476D1 DE 68912476 D1 DE68912476 D1 DE 68912476D1 DE 89309685 T DE89309685 T DE 89309685T DE 68912476 T DE68912476 T DE 68912476T DE 68912476 D1 DE68912476 D1 DE 68912476D1
Authority
DE
Germany
Prior art keywords
antihypertensive agent
thienopyrans
substituted
substituted thienopyrans
antihypertensive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89309685T
Other languages
English (en)
Other versions
DE68912476T2 (de
Inventor
Jeffery B Press
Pauline Sanfilippo
James J Mcnally
Robert Falotico
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/249,043 external-priority patent/US4992435A/en
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of DE68912476D1 publication Critical patent/DE68912476D1/de
Application granted granted Critical
Publication of DE68912476T2 publication Critical patent/DE68912476T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DE68912476T 1988-09-23 1989-09-22 Substituierte Thienopyrane als blutdrucksenkendes Mittel. Expired - Fee Related DE68912476T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/249,043 US4992435A (en) 1988-09-23 1988-09-23 Substituted thienopyrans as antihypertensive agents
US40162889A 1989-09-06 1989-09-06

Publications (2)

Publication Number Publication Date
DE68912476D1 true DE68912476D1 (de) 1994-03-03
DE68912476T2 DE68912476T2 (de) 1994-05-19

Family

ID=26939780

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68912476T Expired - Fee Related DE68912476T2 (de) 1988-09-23 1989-09-22 Substituierte Thienopyrane als blutdrucksenkendes Mittel.

Country Status (19)

Country Link
US (2) US5284857A (de)
EP (1) EP0360621B1 (de)
JP (1) JPH02174781A (de)
KR (1) KR920008824B1 (de)
CN (1) CN1032210C (de)
AU (1) AU619896B2 (de)
CA (1) CA1338419C (de)
DE (1) DE68912476T2 (de)
DK (1) DK469189A (de)
ES (1) ES2062027T3 (de)
FI (1) FI894491A (de)
HU (1) HUT54162A (de)
IE (1) IE63301B1 (de)
IL (1) IL91709A (de)
MY (1) MY129947A (de)
NO (1) NO172802C (de)
NZ (1) NZ230711A (de)
PH (2) PH30818A (de)
PT (1) PT91787B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63935B1 (en) * 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
DE3925719A1 (de) * 1989-08-03 1991-02-07 Bayer Ag Substituierte thienopyranone, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von parasiten
NZ240933A (en) * 1990-12-21 1993-05-26 Ortho Pharma Corp Preparing enantiomerically pure thienopyran derivatives
GB9225860D0 (en) * 1992-12-11 1993-02-03 Smithkline Beecham Plc Novel treatment
GB9411635D0 (en) 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
DE19706892A1 (de) * 1997-02-21 1998-08-27 Hoechst Ag Sulfonamid-substituierte Thiophene, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0895994A3 (de) * 1997-08-05 1999-12-15 Hoechst Marion Roussel Deutschland GmbH Sulfonamid-substituierte Pyranopyridine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
GB9909792D0 (en) 1998-12-04 1999-06-23 Cambridge Bioclinical Limited Potassium channel activators and their use
AU6019900A (en) * 1999-11-24 2001-06-04 Sumika Fine Chemicals Co., Ltd. Anhydrous mirtazapine crystals and process for producing the same
WO2016209996A1 (en) 2015-06-23 2016-12-29 University Of Oregon Phosphorus-containing heterocycles and a method for making and using

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308063D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
EP0126311B1 (de) * 1983-05-18 1989-09-13 Beecham Group Plc Benzopyran-Derivate.
DE3475786D1 (de) * 1983-09-01 1989-02-02 Beecham Group Plc Chromanol derivatives
GB8324547D0 (en) * 1983-09-14 1983-10-19 Beecham Group Plc Compounds
US4797413A (en) * 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4824968A (en) * 1984-12-12 1989-04-25 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
DE3682331D1 (de) * 1985-06-08 1991-12-12 Beecham Group Plc Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8613786D0 (en) * 1986-06-06 1986-07-09 Beecham Group Plc Active compounds
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
US5030736A (en) * 1988-09-23 1991-07-09 Ortho Pharmaceutical Corporation Substituted thienopyrans
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
IE63935B1 (en) * 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
US5120757A (en) * 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
DE3925719A1 (de) * 1989-08-03 1991-02-07 Bayer Ag Substituierte thienopyranone, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von parasiten

Also Published As

Publication number Publication date
NO893775D0 (no) 1989-09-22
KR900004745A (ko) 1990-04-12
NO172802B (no) 1993-06-01
PH30818A (en) 1997-10-17
CN1042152A (zh) 1990-05-16
PH30773A (en) 1997-10-17
JPH02174781A (ja) 1990-07-06
AU4170889A (en) 1990-03-29
US5284857A (en) 1994-02-08
EP0360621B1 (de) 1994-01-19
KR920008824B1 (ko) 1992-10-09
NZ230711A (en) 1990-10-26
CN1032210C (zh) 1996-07-03
CA1338419C (en) 1996-06-25
IL91709A (en) 1994-07-31
IE63301B1 (en) 1995-04-05
DK469189D0 (da) 1989-09-22
HUT54162A (en) 1991-01-28
US5378713A (en) 1995-01-03
EP0360621A1 (de) 1990-03-28
ES2062027T3 (es) 1994-12-16
NO893775L (no) 1990-03-26
PT91787A (pt) 1990-03-30
NO172802C (no) 1993-09-08
PT91787B (pt) 1995-05-31
AU619896B2 (en) 1992-02-06
IL91709A0 (en) 1990-06-10
IE893045L (en) 1990-03-23
MY129947A (en) 2007-05-31
DE68912476T2 (de) 1994-05-19
FI894491A0 (fi) 1989-09-22
FI894491A (fi) 1990-03-24
DK469189A (da) 1990-03-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee