DE68908538D1 - Thromboxan a2-antagonisten. - Google Patents

Thromboxan a2-antagonisten.

Info

Publication number
DE68908538D1
DE68908538D1 DE8989313036T DE68908538T DE68908538D1 DE 68908538 D1 DE68908538 D1 DE 68908538D1 DE 8989313036 T DE8989313036 T DE 8989313036T DE 68908538 T DE68908538 T DE 68908538T DE 68908538 D1 DE68908538 D1 DE 68908538D1
Authority
DE
Germany
Prior art keywords
thromboxan
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989313036T
Other languages
English (en)
Other versions
DE68908538T2 (de
Inventor
Robert Bruce Garland
Masateru Miyano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of DE68908538D1 publication Critical patent/DE68908538D1/de
Publication of DE68908538T2 publication Critical patent/DE68908538T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
    • C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0091—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is bridged condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE89313036T 1988-12-13 1989-12-13 Thromboxan A2-Antagonisten. Expired - Fee Related DE68908538T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/283,675 US4992581A (en) 1988-12-13 1988-12-13 Novel methods of manufacturing thromboxane A2 antagonists

Publications (2)

Publication Number Publication Date
DE68908538D1 true DE68908538D1 (de) 1993-09-23
DE68908538T2 DE68908538T2 (de) 1993-12-02

Family

ID=23087078

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89313036T Expired - Fee Related DE68908538T2 (de) 1988-12-13 1989-12-13 Thromboxan A2-Antagonisten.

Country Status (6)

Country Link
US (1) US4992581A (de)
EP (1) EP0373915B1 (de)
JP (1) JPH03502460A (de)
DE (1) DE68908538T2 (de)
GB (1) GB2226558B (de)
WO (1) WO1990006917A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202022102064U1 (de) 2022-04-19 2022-05-24 Jul. Niederdrenk Gmbh & Co. Kg Sperrvorrichtung für Fensterbeschläge

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980001381A1 (en) * 1979-01-05 1980-07-10 R Jones Substituted bicyclo (2,2,1) heptanes and hept-2-enes
JPH0259143B2 (de) * 1979-01-05 1990-12-11 Nat Res Dev
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
US4456617A (en) * 1983-01-12 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction

Also Published As

Publication number Publication date
DE68908538T2 (de) 1993-12-02
GB2226558B (en) 1992-06-17
GB8928217D0 (en) 1990-02-14
EP0373915A1 (de) 1990-06-20
US4992581A (en) 1991-02-12
GB2226558A (en) 1990-07-04
WO1990006917A1 (en) 1990-06-28
EP0373915B1 (de) 1993-08-18
JPH03502460A (ja) 1991-06-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee