DE60330050D1 - METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS - Google Patents
METHOD FOR PRODUCING PYRIMIDINE COMPOUNDSInfo
- Publication number
- DE60330050D1 DE60330050D1 DE60330050T DE60330050T DE60330050D1 DE 60330050 D1 DE60330050 D1 DE 60330050D1 DE 60330050 T DE60330050 T DE 60330050T DE 60330050 T DE60330050 T DE 60330050T DE 60330050 D1 DE60330050 D1 DE 60330050D1
- Authority
- DE
- Germany
- Prior art keywords
- pyrimidine compounds
- producing pyrimidine
- producing
- compounds
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0229243A GB0229243D0 (en) | 2002-12-16 | 2002-12-16 | Compounds and process |
GB0303589A GB0303589D0 (en) | 2003-02-17 | 2003-02-17 | Compounds and process |
GB0318515A GB0318515D0 (en) | 2003-08-07 | 2003-08-07 | Compounds and process |
PCT/GB2003/005359 WO2004054986A2 (en) | 2002-12-16 | 2003-12-09 | Process for the preparation of pyrimidine compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60330050D1 true DE60330050D1 (en) | 2009-12-24 |
Family
ID=32600665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60330050T Expired - Lifetime DE60330050D1 (en) | 2002-12-16 | 2003-12-09 | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS |
Country Status (23)
Country | Link |
---|---|
US (2) | US7524955B2 (en) |
EP (2) | EP2088142A3 (en) |
JP (2) | JP4579821B2 (en) |
KR (1) | KR101060215B1 (en) |
AR (1) | AR042355A1 (en) |
AT (1) | ATE448209T1 (en) |
AU (1) | AU2003288443B2 (en) |
BR (1) | BR0317313A (en) |
CA (1) | CA2509344C (en) |
CY (1) | CY1110605T1 (en) |
DE (1) | DE60330050D1 (en) |
DK (1) | DK1578731T3 (en) |
ES (1) | ES2335279T3 (en) |
HK (1) | HK1080477A1 (en) |
IL (1) | IL168884A (en) |
MX (1) | MXPA05006425A (en) |
MY (1) | MY138051A (en) |
NO (2) | NO330983B1 (en) |
NZ (1) | NZ540722A (en) |
PT (1) | PT1578731E (en) |
SI (1) | SI1578731T1 (en) |
TW (1) | TWI322145B (en) |
WO (1) | WO2004054986A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
NL1015744C2 (en) * | 2000-07-19 | 2002-01-22 | Dsm Nv | Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) acetic acid derivatives. |
AU2002318041B2 (en) | 2001-07-13 | 2008-01-03 | Astrazeneca Uk Limited | Preparation of aminopyrimidine compounds |
EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
KR20030092446A (en) * | 2002-05-29 | 2003-12-06 | 주식회사 한국토종약초연구소 | Composition comprising an extract of Lophatherum gracile BRONGN. Inhibiting HCV activity |
EP1375493A1 (en) | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
ATE448209T1 (en) | 2002-12-16 | 2009-11-15 | Astrazeneca Uk Ltd | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS |
GB0312896D0 (en) * | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
UY28501A1 (en) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | CHEMICAL COMPOUNDS |
GB0324791D0 (en) * | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
GB0428328D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
US8153791B2 (en) | 2005-12-21 | 2012-04-10 | Janssen Pharmaceutica N.V. | Substituted pyrimidinyl oxime kinase inhibitors |
WO2007109783A2 (en) * | 2006-03-23 | 2007-09-27 | Janssen Pharmaceutica, N.V. | Substituted pyrimidine kinase inhibitors |
TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
BR112012029627B1 (en) | 2010-05-21 | 2020-11-10 | Cooper Technologies Company | adapter and method for coupling together |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3278001A (en) * | 1965-02-02 | 1966-10-11 | Charles C Andrews | Bearing assembly for auger conveyors |
US4698340A (en) | 1984-07-19 | 1987-10-06 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine derivatives, processes for preparation thereof and composition containing the same |
US4689414A (en) * | 1986-02-24 | 1987-08-25 | E. R. Squibb & Sons, Inc. | 2-(substituted imino)-6-aryl-3,6-dihydro-4-substituted-1,5(2H)-pyrimidinecarboxylic acids and analogs |
JPH03501613A (en) | 1988-10-06 | 1991-04-11 | サンド・アクチエンゲゼルシヤフト | Pyrimidinyl-substituted hydroxy acids, lactones and esters and pharmaceutical compositions containing them |
FR2665159B1 (en) | 1990-07-24 | 1992-11-13 | Rhone Poulenc Sante | NEW PYRIDINE AND QUINOLEIN DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
JP2648897B2 (en) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | Pyrimidine derivatives |
WO1993008823A1 (en) | 1991-11-06 | 1993-05-13 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
JP3197971B2 (en) | 1993-03-01 | 2001-08-13 | 塩野義製薬株式会社 | Method for synthesizing 5-carboalkoxypyrimidine derivative |
US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
NZ264063A (en) | 1993-08-13 | 1995-11-27 | Nihon Nohyaku Co Ltd | N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions |
NZ297278A (en) | 1994-11-16 | 1999-06-29 | Synaptic Pharma Corp | 4-aryl dihydropyrimidine derivatives end medicaments |
DE19517186A1 (en) | 1995-05-11 | 1996-11-14 | Bayer Ag | Process for the preparation of substituted 2-fluoropyrimidines |
FR2741620B1 (en) | 1995-11-28 | 1997-12-26 | Oreal | PROCESS FOR THE PREPARATION OF COMPOUNDS WITH A BETA-HYDROXY -DELTA-LACTONE GROUP ANALOGS OF (+) COMPACTIN AND (+) MEVINOLINE |
US6278001B1 (en) | 1995-11-28 | 2001-08-21 | L'oréal | Method for preparing (+) compactin and (+) mevinolin analog compounds having a β-hydroxy-δ-lactone grouping |
SK77398A3 (en) | 1995-12-14 | 1999-02-11 | Merck & Co Inc | Process for making dihydropyrimidinones |
US5958934A (en) | 1996-05-23 | 1999-09-28 | Syntex (U.S.A.) Inc. | Aryl pyrimidine derivatives and uses thereof |
SE9702563D0 (en) | 1997-07-02 | 1997-07-02 | Astra Ab | Compounds |
CA2297889A1 (en) | 1997-08-05 | 1999-02-18 | Norihiro Ikemoto | Alpha 1a adrenergic receptor antagonist |
GB9903472D0 (en) | 1999-02-17 | 1999-04-07 | Zeneca Ltd | Chemical process |
AU5568400A (en) * | 1999-06-23 | 2001-01-09 | Ajinomoto Co., Inc. | Novel dihydropyrimidine derivatives |
HU228303B1 (en) * | 1999-07-13 | 2013-03-28 | Lonza Ag | Process for preparing 2-amino-4-(4-fluorphenyl)-6-alkylpyrimidine-5-carboxylate |
GB0003305D0 (en) | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
WO2001072706A1 (en) | 2000-03-28 | 2001-10-04 | Biocon India Limited | Synthesis of [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin) |
GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
GB0011163D0 (en) | 2000-05-10 | 2000-06-28 | Astrazeneca Ab | Chemical compound |
NL1015744C2 (en) | 2000-07-19 | 2002-01-22 | Dsm Nv | Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) acetic acid derivatives. |
AU2002318041B2 (en) * | 2001-07-13 | 2008-01-03 | Astrazeneca Uk Limited | Preparation of aminopyrimidine compounds |
EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
KR100511533B1 (en) | 2002-04-09 | 2005-08-31 | 임광민 | CHIRAL INTERMEDIATE, PROCESS FOR THE PRODUCTION THEREOF, AND PROCESS FOR THE PRODUCTION OF HMG-CoA REDUCTASE INHIBITOR |
EP1375493A1 (en) | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
ATE448209T1 (en) | 2002-12-16 | 2009-11-15 | Astrazeneca Uk Ltd | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS |
WO2004103977A2 (en) | 2003-05-21 | 2004-12-02 | Ciba Specialty Chemicals Holding Inc. | Process for the preparation of pyrimidine derivatives |
GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
UY28501A1 (en) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | CHEMICAL COMPOUNDS |
GB0321827D0 (en) | 2003-09-18 | 2003-10-15 | Astrazeneca Uk Ltd | Chemical compounds |
GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
US20050159615A1 (en) | 2003-12-24 | 2005-07-21 | Entire Interest. | Process for preparation of statins with high syn to anti ratio |
GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
-
2003
- 2003-12-09 AT AT03780362T patent/ATE448209T1/en active
- 2003-12-09 WO PCT/GB2003/005359 patent/WO2004054986A2/en active Application Filing
- 2003-12-09 MX MXPA05006425A patent/MXPA05006425A/en active IP Right Grant
- 2003-12-09 DK DK03780362.4T patent/DK1578731T3/en active
- 2003-12-09 SI SI200331722T patent/SI1578731T1/en unknown
- 2003-12-09 DE DE60330050T patent/DE60330050D1/en not_active Expired - Lifetime
- 2003-12-09 PT PT03780362T patent/PT1578731E/en unknown
- 2003-12-09 EP EP09159247A patent/EP2088142A3/en not_active Ceased
- 2003-12-09 US US10/537,723 patent/US7524955B2/en not_active Expired - Fee Related
- 2003-12-09 CA CA2509344A patent/CA2509344C/en not_active Expired - Fee Related
- 2003-12-09 JP JP2005502458A patent/JP4579821B2/en not_active Expired - Fee Related
- 2003-12-09 EP EP03780362A patent/EP1578731B1/en not_active Expired - Lifetime
- 2003-12-09 KR KR1020057010964A patent/KR101060215B1/en not_active IP Right Cessation
- 2003-12-09 AU AU2003288443A patent/AU2003288443B2/en not_active Ceased
- 2003-12-09 BR BR0317313-5A patent/BR0317313A/en not_active IP Right Cessation
- 2003-12-09 ES ES03780362T patent/ES2335279T3/en not_active Expired - Lifetime
- 2003-12-09 NZ NZ540722A patent/NZ540722A/en not_active IP Right Cessation
- 2003-12-10 AR ARP030104541A patent/AR042355A1/en unknown
- 2003-12-12 MY MYPI20034768A patent/MY138051A/en unknown
- 2003-12-16 TW TW092135557A patent/TWI322145B/en not_active IP Right Cessation
-
2005
- 2005-05-30 IL IL168884A patent/IL168884A/en not_active IP Right Cessation
- 2005-06-08 NO NO20052781A patent/NO330983B1/en not_active IP Right Cessation
-
2006
- 2006-01-12 HK HK06100506.1A patent/HK1080477A1/en not_active IP Right Cessation
-
2009
- 2009-03-16 US US12/404,575 patent/US8273878B2/en not_active Expired - Fee Related
-
2010
- 2010-01-11 CY CY20101100025T patent/CY1110605T1/en unknown
- 2010-06-23 JP JP2010142779A patent/JP5318037B2/en not_active Expired - Fee Related
-
2011
- 2011-03-10 NO NO20110366A patent/NO20110366L/en not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE498621T1 (en) | METHOD FOR PRODUCING SUBSTITUTED PYRIMIDINES | |
DE60221399D1 (en) | METHOD FOR PRODUCING MEDIUM-DISTILLATES | |
ATE340819T1 (en) | METHOD FOR PRODUCING POLYAMIDES | |
ATE403641T1 (en) | METHOD FOR PRODUCING O-DESMETHYLVENLAFAXIN | |
DE60220646D1 (en) | PROCESS FOR PRODUCING COMPOUND PROFILES | |
ATA11912002A (en) | METHOD FOR PRODUCING FAKE-SECURE IDENTIFICATION FEATURES | |
DE60230908D1 (en) | METHOD FOR PRODUCING POLYARYLENETHERS | |
DE60327788D1 (en) | METHOD FOR PRODUCING POLYTRIMETHYLENEEPHTHALSE FIBERS | |
DE60330050D1 (en) | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS | |
ATE315099T1 (en) | METHOD FOR PRODUCING TAGATOSE | |
DE50308650D1 (en) | METHOD FOR PRODUCING CELLULOSECARBAMATE FORM BODIES | |
ATE456569T1 (en) | METHOD FOR PRODUCING 6-ALKYLIDE PENEM DERIVATIVES | |
ATE287882T1 (en) | METHOD FOR PRODUCING IMIDAZOLE COMPOUNDS | |
ATE553103T1 (en) | METHOD FOR PRODUCING (S)-PANTOPRAZOLE | |
DE50303611D1 (en) | METHOD FOR PRODUCING POLYISOBUTES | |
ATE441662T1 (en) | METHOD FOR PRODUCING ECHINOCANDINE DERIVATIVES | |
ATE521596T1 (en) | METHOD FOR PRODUCING PYRIMIDINE COMPOUNDS | |
DE50200870D1 (en) | METHOD FOR PRODUCING HYDROXYALKYLPOLYSILOXANES | |
ATE402138T1 (en) | METHOD FOR PRODUCING 2-AMINOINDANDERIVATES | |
DE502004004318D1 (en) | METHOD FOR PRODUCING METAL-MATRIX-COMPOSITE MATERIALS | |
ATE471941T1 (en) | METHOD FOR PRODUCING THIAZOLOPYRIMIDINES | |
ATE371642T1 (en) | METHOD FOR PRODUCING 3-METHYLTHIOPROPANAL | |
ATE382621T1 (en) | METHOD FOR PRODUCING NEVIRAPINE | |
ATE477244T1 (en) | METHOD FOR PRODUCING BENGAMIDE DERIVATIVES | |
ATE468323T1 (en) | METHOD FOR PRODUCING 2-CYAN-3-HYDROXY-N-(PHENYL)BUT-2-ENAMIDS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |