DE60216570D1 - METHOD FOR DETECTING ALZHEIMER DISEASE - Google Patents
METHOD FOR DETECTING ALZHEIMER DISEASEInfo
- Publication number
- DE60216570D1 DE60216570D1 DE60216570T DE60216570T DE60216570D1 DE 60216570 D1 DE60216570 D1 DE 60216570D1 DE 60216570 T DE60216570 T DE 60216570T DE 60216570 T DE60216570 T DE 60216570T DE 60216570 D1 DE60216570 D1 DE 60216570D1
- Authority
- DE
- Germany
- Prior art keywords
- alzheimer disease
- detecting alzheimer
- disease
- alzheimer
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/99—Isomerases (5.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Abstract
The present invention relates diagnostic screens for Alzheimer's disease, and in particular to diagnostic tests based on screening for the presence of cellular changes that occur early in the pathology of Alzheimer's disease.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0106051 | 2001-03-12 | ||
GBGB0106051.6A GB0106051D0 (en) | 2001-03-12 | 2001-03-12 | Diagnostic screens for alzheimer's disease |
PCT/GB2002/001137 WO2002073212A2 (en) | 2001-03-12 | 2002-03-12 | Diagnostic screens for alzheimer's disease |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60216570D1 true DE60216570D1 (en) | 2007-01-18 |
DE60216570T2 DE60216570T2 (en) | 2007-04-05 |
Family
ID=9910482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60216570T Expired - Lifetime DE60216570T2 (en) | 2001-03-12 | 2002-03-12 | METHOD FOR DETECTING ALZHEIMER DISEASE |
Country Status (9)
Country | Link |
---|---|
US (1) | US20040132113A1 (en) |
EP (2) | EP1724588B1 (en) |
JP (3) | JP4430306B2 (en) |
AT (1) | ATE347698T1 (en) |
AU (1) | AU2002238766A1 (en) |
DE (1) | DE60216570T2 (en) |
ES (1) | ES2272673T3 (en) |
GB (1) | GB0106051D0 (en) |
WO (1) | WO2002073212A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0117645D0 (en) | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
GB0311835D0 (en) * | 2003-05-22 | 2003-06-25 | Isis Innovation | Susceptibility gene for alzheimer's disease |
ES2330465T3 (en) * | 2006-02-03 | 2009-12-10 | Mtm Laboratories Ag | PROCEDURE TO PERFORM A DENATURING IMMUNO TEST. |
WO2010112034A2 (en) * | 2009-04-02 | 2010-10-07 | Aarhus Universitet | Compositions and methods for treatment and diagnosis of synucleinopathies |
GB0912394D0 (en) * | 2009-07-16 | 2009-08-26 | Univ Birmingham | Screening methods |
GB201112246D0 (en) * | 2011-07-15 | 2011-08-31 | Univ Birmingham | Diagnosis of alzheimer's disease |
GB201212334D0 (en) | 2012-07-11 | 2012-08-22 | Warwick The | Therapeutic targets for alzheimers disease |
CN103808917B (en) * | 2014-03-16 | 2015-11-04 | 国家烟草质量监督检验中心 | A kind of tobacco juice for electronic smoke cell proliferation toxicity assessment method |
CN103808919B (en) * | 2014-03-16 | 2015-11-18 | 国家烟草质量监督检验中心 | A kind of cigarette smoke propagation toxicity assessment method of mixing based on bromodeoxyuridine nucleosides |
WO2019113277A1 (en) * | 2017-12-08 | 2019-06-13 | NeuroDiagnostics LLC | Diagnosing disease via gene expression profile in synchronized cells |
KR102478811B1 (en) | 2020-08-21 | 2022-12-16 | 재단법인대구경북과학기술원 | Novel biomarker composition for diagnosis of Alzheimer's Disease based on multiplex PCR platform |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4544993A (en) * | 1992-06-24 | 1994-01-24 | Cortex Pharmaceuticals, Inc. | Use of calpain inhibitors in the inhibition and treatment of medical conditions associated with increased calpain activity |
US5773219A (en) * | 1992-10-06 | 1998-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Process for detecting Alzheimer disease using cultured cells |
US6022683A (en) * | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
CA2222813A1 (en) * | 1996-04-04 | 1997-10-16 | University Of South Florida | Variant presenilin-2 genes |
US6342350B1 (en) * | 1997-09-05 | 2002-01-29 | The General Hospital Corporation | Alpha-2-macroglobulin diagnostic test |
WO2000079000A1 (en) * | 1999-06-22 | 2000-12-28 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Method for detection of early-onset alzheimer's disease |
-
2001
- 2001-03-12 GB GBGB0106051.6A patent/GB0106051D0/en not_active Ceased
-
2002
- 2002-03-12 AU AU2002238766A patent/AU2002238766A1/en not_active Abandoned
- 2002-03-12 EP EP06014441.7A patent/EP1724588B1/en not_active Expired - Lifetime
- 2002-03-12 DE DE60216570T patent/DE60216570T2/en not_active Expired - Lifetime
- 2002-03-12 AT AT02704967T patent/ATE347698T1/en not_active IP Right Cessation
- 2002-03-12 ES ES02704967T patent/ES2272673T3/en not_active Expired - Lifetime
- 2002-03-12 EP EP02704967A patent/EP1370870B9/en not_active Expired - Lifetime
- 2002-03-12 WO PCT/GB2002/001137 patent/WO2002073212A2/en active IP Right Grant
- 2002-03-12 JP JP2002572422A patent/JP4430306B2/en not_active Expired - Fee Related
-
2003
- 2003-09-10 US US10/659,578 patent/US20040132113A1/en not_active Abandoned
-
2008
- 2008-05-29 JP JP2008141226A patent/JP4541429B2/en not_active Expired - Lifetime
-
2010
- 2010-03-04 JP JP2010047861A patent/JP2010166922A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP4430306B2 (en) | 2010-03-10 |
GB0106051D0 (en) | 2001-05-02 |
AU2002238766A1 (en) | 2002-09-24 |
US20040132113A1 (en) | 2004-07-08 |
DE60216570T2 (en) | 2007-04-05 |
JP2010166922A (en) | 2010-08-05 |
ES2272673T3 (en) | 2007-05-01 |
WO2002073212A2 (en) | 2002-09-19 |
EP1370870B9 (en) | 2009-12-02 |
EP1724588A3 (en) | 2007-09-05 |
ATE347698T1 (en) | 2006-12-15 |
EP1370870B1 (en) | 2006-12-06 |
EP1370870A2 (en) | 2003-12-17 |
JP2008245654A (en) | 2008-10-16 |
EP1724588B1 (en) | 2017-05-03 |
EP1724588A2 (en) | 2006-11-22 |
JP4541429B2 (en) | 2010-09-08 |
JP2004531244A (en) | 2004-10-14 |
WO2002073212A3 (en) | 2003-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |