DE60203895D1 - Verwendung von n-acetyl-d-glucosamin bei der herstellung eines arzneimittels zur unterdrückung der nebenwirkungen von strahlentherapie und chemotherapie - Google Patents
Verwendung von n-acetyl-d-glucosamin bei der herstellung eines arzneimittels zur unterdrückung der nebenwirkungen von strahlentherapie und chemotherapieInfo
- Publication number
- DE60203895D1 DE60203895D1 DE60203895T DE60203895T DE60203895D1 DE 60203895 D1 DE60203895 D1 DE 60203895D1 DE 60203895 T DE60203895 T DE 60203895T DE 60203895 T DE60203895 T DE 60203895T DE 60203895 D1 DE60203895 D1 DE 60203895D1
- Authority
- DE
- Germany
- Prior art keywords
- glucosamine
- acetyl
- medicament
- manufacture
- radiotherapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 title abstract 3
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 3
- 229950006780 n-acetylglucosamine Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000002512 chemotherapy Methods 0.000 title 1
- 238000001959 radiotherapy Methods 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01104882A CN1131036C (zh) | 2001-02-28 | 2001-02-28 | N－乙酰－d－氨基葡萄糖在制备抑制放化疗副反应药物中的应用 |
| CN01104882 | 2001-02-28 | ||
| PCT/CN2002/000119 WO2002067946A1 (fr) | 2001-02-28 | 2002-02-28 | Utilisation de la n-acetyl-d-glucosamine dans la preparation de compositions pharmaceutiques utilisees dans la suppression des effets secondaires causes par la radiotherapie et la chimiotherapie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60203895D1 true DE60203895D1 (de) | 2005-06-02 |
| DE60203895T2 DE60203895T2 (de) | 2005-09-29 |
Family
ID=4654071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60203895T Expired - Lifetime DE60203895T2 (de) | 2001-02-28 | 2002-02-28 | Verwendung von n-acetyl-d-glucosamin bei der herstellung eines arzneimittels zur unterdrückung der nebenwirkungen von strahlentherapie und chemotherapie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7037904B2 (de) |
| EP (1) | EP1374873B8 (de) |
| CN (1) | CN1131036C (de) |
| AT (1) | ATE293983T1 (de) |
| DE (1) | DE60203895T2 (de) |
| HK (1) | HK1061530A1 (de) |
| WO (1) | WO2002067946A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1210038C (zh) | 2003-03-27 | 2005-07-13 | 中国人民解放军第三军医大学 | N－乙酰氨基葡萄糖在制备用于治疗毒物和药物中毒致脏器损伤的药物中的应用 |
| JP2007506645A (ja) * | 2003-09-17 | 2007-03-22 | 中国人民解放▲軍▼第三▲軍▼医大学 | 抗腫瘍および抗転移のための製剤の製造におけるｎ−アセチル−ｄ−グルコサミンの使用 |
| CN101155591B (zh) * | 2005-08-03 | 2012-01-18 | 国立癌中心 | 可用作tg抑制剂的葡萄糖胺及其衍生物 |
| CN104267185B (zh) * | 2014-09-12 | 2016-05-18 | 范飞舟 | 检测肿瘤的试剂盒及其专用识别n-乙酰氨基葡萄糖的物质 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4216208A (en) * | 1978-07-31 | 1980-08-05 | Proter S.P.A. | N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity |
| US4710493A (en) * | 1984-08-14 | 1987-12-01 | Albert Landsberger | Therapeutic agent for the use in cancer treatment |
| CA1340994C (en) * | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| US5229374A (en) | 1992-01-28 | 1993-07-20 | Burton Albert F | Method for treatment of lower gastrointestinal tract disorders |
| AU3881493A (en) | 1992-03-19 | 1993-10-21 | University Of British Columbia, The | Method and composition for suppression of side effects of anti-inflammatory drugs |
| CN1095366C (zh) * | 1996-12-27 | 2002-12-04 | 中国人民解放军第三军医大学 | N－乙酰－d－氨基葡萄糖在制备治疗肠道疾病药物中的应用 |
| CN1067246C (zh) * | 1996-12-27 | 2001-06-20 | 中国人民解放军第三军医大学 | N－乙酰－d－氨基葡萄糖在制备治疗皮肤癣菌的药物中的应用 |
| CN1067245C (zh) * | 1996-12-27 | 2001-06-20 | 中国人民解放军第三军医大学 | N－乙酰－d－氨基葡萄糖在制备治疗呼吸道疾病的药物中的应用 |
-
2001
- 2001-02-28 CN CN01104882A patent/CN1131036C/zh not_active Expired - Fee Related
-
2002
- 2002-02-28 WO PCT/CN2002/000119 patent/WO2002067946A1/zh not_active Application Discontinuation
- 2002-02-28 DE DE60203895T patent/DE60203895T2/de not_active Expired - Lifetime
- 2002-02-28 US US10/469,327 patent/US7037904B2/en not_active Expired - Fee Related
- 2002-02-28 AT AT02703474T patent/ATE293983T1/de not_active IP Right Cessation
- 2002-02-28 EP EP02703474A patent/EP1374873B8/de not_active Expired - Lifetime
-
2004
- 2004-06-24 HK HK04104522A patent/HK1061530A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002067946A1 (fr) | 2002-09-06 |
| US20040077596A1 (en) | 2004-04-22 |
| HK1061530A1 (en) | 2004-09-24 |
| EP1374873B1 (de) | 2005-04-27 |
| US7037904B2 (en) | 2006-05-02 |
| EP1374873A4 (de) | 2004-08-11 |
| CN1131036C (zh) | 2003-12-17 |
| DE60203895T2 (de) | 2005-09-29 |
| ATE293983T1 (de) | 2005-05-15 |
| EP1374873B8 (de) | 2005-06-29 |
| CN1372929A (zh) | 2002-10-09 |
| EP1374873A1 (de) | 2004-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: THIRD MILITARY MEDICAL UNIVERSITY CHINESE PEOPLE'S Owner name: BIO-WAVE INSTITUTE OF SUZHOU HI-TECH NEW DISTRICT Owner name: BEIJING SINO-HONGKONG DAFU SCIENCE & TECHNOLOGY OF |
|
| 8364 | No opposition during term of opposition |