DE602006013094D1 - CANCER AGENT - Google Patents

CANCER AGENT

Info

Publication number
DE602006013094D1
DE602006013094D1 DE602006013094T DE602006013094T DE602006013094D1 DE 602006013094 D1 DE602006013094 D1 DE 602006013094D1 DE 602006013094 T DE602006013094 T DE 602006013094T DE 602006013094 T DE602006013094 T DE 602006013094T DE 602006013094 D1 DE602006013094 D1 DE 602006013094D1
Authority
DE
Germany
Prior art keywords
cancer agent
cancer
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006013094T
Other languages
German (de)
Inventor
Koji Yoshinaga
Daisuke Kawasaki
Yutaka Emori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeria Pharmaceutical Co Ltd
Original Assignee
Zeria Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharmaceutical Co Ltd filed Critical Zeria Pharmaceutical Co Ltd
Publication of DE602006013094D1 publication Critical patent/DE602006013094D1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
DE602006013094T 2005-01-19 2006-01-16 CANCER AGENT Active DE602006013094D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005011158 2005-01-19
PCT/JP2006/300445 WO2006077793A1 (en) 2005-01-19 2006-01-16 Antitumor agent

Publications (1)

Publication Number Publication Date
DE602006013094D1 true DE602006013094D1 (en) 2010-05-06

Family

ID=36692183

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006013094T Active DE602006013094D1 (en) 2005-01-19 2006-01-16 CANCER AGENT

Country Status (18)

Country Link
US (5) US20080161293A1 (en)
EP (1) EP1839662B1 (en)
JP (1) JP4957250B2 (en)
KR (1) KR101285047B1 (en)
CN (1) CN101102776B (en)
AU (1) AU2006207152B2 (en)
BR (1) BRPI0606459A2 (en)
CA (1) CA2594482C (en)
DE (1) DE602006013094D1 (en)
DK (1) DK1839662T3 (en)
ES (1) ES2341728T3 (en)
HK (1) HK1116064A1 (en)
PL (1) PL1839662T3 (en)
PT (1) PT1839662E (en)
RU (1) RU2391982C2 (en)
SI (1) SI1839662T1 (en)
TW (1) TWI399206B (en)
WO (1) WO2006077793A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006013094D1 (en) * 2005-01-19 2010-05-06 Zeria Pharm Co Ltd CANCER AGENT
TWI459948B (en) * 2008-05-15 2014-11-11 Zeria Pharm Co Ltd The use of a 1,5-benzodiazepine derivative or a pharmaceutically acceptable salt thereof for the manufacture of a pain therapeutic agent composition
ES2502940T3 (en) 2008-08-05 2014-10-06 Toray Industries, Inc. Pharmaceutical composition for the treatment and prevention of cancer
PL2325648T3 (en) 2008-08-05 2014-09-30 Toray Industries Method for detecting cancer
KR20120027111A (en) 2009-03-31 2012-03-21 제리아 신야쿠 고교 가부시키 가이샤 Method for manufacturing benzodiazepine derivative
WO2013018885A1 (en) 2011-08-04 2013-02-07 東レ株式会社 Method for detecting pancreatic cancer
KR102056654B1 (en) 2012-07-19 2019-12-17 도레이 카부시키가이샤 Cancer detection method
EP2979700B1 (en) * 2013-03-27 2018-09-26 Taiho Pharmaceutical Co., Ltd. Antitumor agent including low dose irinotecan hydrochloride hydrate
KR102255616B1 (en) 2013-08-09 2021-05-25 도레이 카부시키가이샤 Pharmaceutical composition for treatment and/or prevention of cancer
CN103435562B (en) * 2013-08-26 2016-02-24 华东理工大学 6-replaces Benzodiazepine-2,4-cyclohexadione compounds and uses thereof
BR112016011727A2 (en) 2013-11-22 2017-08-08 CL BioSciences LLC GASTRIN ANTAGONISTS FOR THE TREATMENT AND PREVENTION OF OSTEOPOROSIS
CN108395410A (en) * 2018-05-09 2018-08-14 日照市普达医药科技有限公司 A kind of anilinoquinazoline compound and its application in antitumor drug

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218115A (en) * 1991-04-10 1993-06-08 Merck & Co., Inc. Cholecystokinin antagonists
JPH0840908A (en) * 1994-07-28 1996-02-13 Yamanouchi Pharmaceut Co Ltd Cancerous cell proliferation inhibitor
CN1130351C (en) * 1996-12-10 2003-12-10 泽里新药工业株式会社 1,5-benzodiazepine derivatives
JP2000026434A (en) * 1998-06-05 2000-01-25 Zeria Pharmaceut Co Ltd New 1,5-benzodiazepine derivative
AU4564200A (en) * 1999-04-29 2000-11-17 Aventis Pharma S.A. Method for treating cancer using camptothecin derivatives and 5-fluorouracil
TWI288747B (en) * 1999-12-02 2007-10-21 Zeria Pharm Co Ltd Calcium salts of a 1,5-benzodiazepine derivative, a process for preparing the same, and drugs containing the same as the active ingredient
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
EP1391203A4 (en) * 2001-05-11 2005-09-14 Astellas Pharma Inc Antitumor agents
DE602006013094D1 (en) * 2005-01-19 2010-05-06 Zeria Pharm Co Ltd CANCER AGENT

Also Published As

Publication number Publication date
KR20070095930A (en) 2007-10-01
PL1839662T3 (en) 2010-08-31
PT1839662E (en) 2010-04-28
US20180318314A1 (en) 2018-11-08
EP1839662A4 (en) 2008-05-21
AU2006207152A1 (en) 2006-07-27
HK1116064A1 (en) 2008-12-19
DK1839662T3 (en) 2010-05-10
BRPI0606459A2 (en) 2009-06-30
SI1839662T1 (en) 2010-07-30
CA2594482C (en) 2013-10-01
ES2341728T3 (en) 2010-06-25
US20100143366A1 (en) 2010-06-10
TWI399206B (en) 2013-06-21
KR101285047B1 (en) 2013-07-10
JPWO2006077793A1 (en) 2008-06-19
US20100086553A1 (en) 2010-04-08
EP1839662B1 (en) 2010-03-24
US20170151256A1 (en) 2017-06-01
RU2391982C2 (en) 2010-06-20
CN101102776B (en) 2011-08-24
US20080161293A1 (en) 2008-07-03
CA2594482A1 (en) 2006-07-27
AU2006207152B2 (en) 2011-02-24
CN101102776A (en) 2008-01-09
RU2007131435A (en) 2009-02-27
EP1839662A1 (en) 2007-10-03
JP4957250B2 (en) 2012-06-20
WO2006077793A1 (en) 2006-07-27
TW200637561A (en) 2006-11-01

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