DE602004023753D1 - Verfahren und zusammensetzungen zur herstellung und verwendung fixiert behandelter zellinien und von fixiert behandeltem gewebe bei der in-situ-fluoreszenzhybridisierung - Google Patents

Verfahren und zusammensetzungen zur herstellung und verwendung fixiert behandelter zellinien und von fixiert behandeltem gewebe bei der in-situ-fluoreszenzhybridisierung

Info

Publication number
DE602004023753D1
DE602004023753D1 DE602004023753T DE602004023753T DE602004023753D1 DE 602004023753 D1 DE602004023753 D1 DE 602004023753D1 DE 602004023753 T DE602004023753 T DE 602004023753T DE 602004023753 T DE602004023753 T DE 602004023753T DE 602004023753 D1 DE602004023753 D1 DE 602004023753D1
Authority
DE
Germany
Prior art keywords
tissue
fixed treated
fixed
compositions
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602004023753T
Other languages
English (en)
Inventor
Jon Edelson
Paola Capodieci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aureon Laboratories Inc
Original Assignee
Aureon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aureon Laboratories Inc filed Critical Aureon Laboratories Inc
Publication of DE602004023753D1 publication Critical patent/DE602004023753D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602004023753T 2003-07-21 2004-07-19 Verfahren und zusammensetzungen zur herstellung und verwendung fixiert behandelter zellinien und von fixiert behandeltem gewebe bei der in-situ-fluoreszenzhybridisierung Expired - Fee Related DE602004023753D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/624,233 US6995020B2 (en) 2003-07-21 2003-07-21 Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
PCT/US2004/023207 WO2005010203A2 (en) 2003-07-21 2004-07-19 Treatment of cells for fluorescence in situ hybridization

Publications (1)

Publication Number Publication Date
DE602004023753D1 true DE602004023753D1 (de) 2009-12-03

Family

ID=34079958

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004023753T Expired - Fee Related DE602004023753D1 (de) 2003-07-21 2004-07-19 Verfahren und zusammensetzungen zur herstellung und verwendung fixiert behandelter zellinien und von fixiert behandeltem gewebe bei der in-situ-fluoreszenzhybridisierung

Country Status (7)

Country Link
US (2) US6995020B2 (de)
EP (1) EP1689883B1 (de)
AT (1) ATE446383T1 (de)
AU (1) AU2004260105A1 (de)
CA (1) CA2532467C (de)
DE (1) DE602004023753D1 (de)
WO (1) WO2005010203A2 (de)

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US6995020B2 (en) * 2003-07-21 2006-02-07 Aureon Laboratories, Inc. Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
US7467119B2 (en) * 2003-07-21 2008-12-16 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US8062897B2 (en) * 2003-07-21 2011-11-22 Aureon Laboratories, Inc. Diagnostic histopathology using multiplex gene expression FISH
WO2005086068A2 (en) * 2004-02-27 2005-09-15 Aureon Laboratories, Inc. Methods and systems for predicting occurrence of an event
WO2007001986A2 (en) * 2005-06-20 2007-01-04 Yuling Luo Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations
US7599893B2 (en) * 2005-10-13 2009-10-06 Aureon Laboratories, Inc. Methods and systems for feature selection in machine learning based on feature contribution and model fitness
PT1934607E (pt) * 2005-10-13 2013-11-13 Fundacao D Anna Sommer Champalimaud E Dr Carlos Montez Champalimaud Análise imuno-histoquímica in situ multiplex
WO2007117700A2 (en) 2006-04-07 2007-10-18 The Trustees Of The University Of Pennsylvania In situ cloning from pathological tissue specimens
US8060348B2 (en) * 2006-08-07 2011-11-15 General Electric Company Systems for analyzing tissue samples
US20080032321A1 (en) * 2006-08-07 2008-02-07 General Electric Company System and methods for analyzing images of tissue samples
US8131476B2 (en) * 2006-08-07 2012-03-06 General Electric Company System and method for co-registering multi-channel images of a tissue micro array
US9779213B2 (en) 2008-07-25 2017-10-03 Fundacao D. Anna Sommer Champalimaud E Dr. Carlos Montez Champalimaud System for evaluating a pathological stage of prostate cancer
CA3074969C (en) * 2008-07-25 2023-06-13 Fundacao D. Anna Sommer Champalimaud E Dr. Carlos Montez Champalimaud Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081926A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081915A1 (en) * 2008-09-29 2010-04-01 Searete Llc, Alimited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081916A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware. Histological facilitation systems and methods
US20100081928A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological Facilitation systems and methods
US20100081927A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081131A1 (en) * 2008-10-01 2010-04-01 Ach Robert A Identification of microbes using oligonucleotide based in situ hybridization
WO2010065775A2 (en) 2008-12-03 2010-06-10 The United States Government As Represented By The Department Of Veterans Affairs Pressure-assisted molecular recovery (pamr) of biomolecules, pressure-assisted antigen retrieval (paar), and pressure-assisted tissue histology (path)
WO2012016242A2 (en) 2010-07-30 2012-02-02 Aureon Biosciences, Inc. Systems and methods for segmentation and processing of tissue images and feature extraction from same for treating, diagnosing, or predicting medical conditions
EP2625502B1 (de) 2010-10-06 2018-09-05 Biocare Medical, LLC Verfahren und system zur effizienten verarbeitung biologischer proben
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
EP2802671B1 (de) 2011-12-12 2018-07-18 Cellay, Inc. Verfahren und kits für den in-situ-nachweis einer zielnucleinsäure in einer biologischen probe bei raumtemperatur
US9278401B2 (en) * 2013-02-11 2016-03-08 International Business Machines Corporation Fill head interface with combination vacuum pressure chamber
WO2016018963A1 (en) 2014-07-30 2016-02-04 President And Fellows Of Harvard College Probe library construction
CN108368543B (zh) 2015-10-12 2023-06-13 领先细胞医疗诊断有限公司 高噪声样品中原位检测核苷酸变体及相关的组合物和方法
KR20180100607A (ko) * 2016-01-07 2018-09-11 크리에티브이 마이크로테크, 인크. 순차적인 형광 소광 및 재염색을 이용한 생물학적 시료의 다중-표현형적 서브타이핑
US11788123B2 (en) 2017-05-26 2023-10-17 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
EP3803686A4 (de) * 2018-05-24 2022-03-16 University of Pittsburgh - of the Commonwealth System of Higher Education Vorhersage von krebsrezidiven aus räumlichen multiparametrischen zellulären und subzellulären bildgebungsdaten
CN109035415B (zh) * 2018-07-03 2023-05-16 百度在线网络技术（北京）有限公司 虚拟模型的处理方法、装置、设备和计算机可读存储介质
CN110208056B (zh) * 2019-06-06 2021-08-31 厦门大学附属第一医院 胃癌her-2 fish的组织芯片制作方法

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US6544798B1 (en) * 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6534266B1 (en) 1999-04-22 2003-03-18 Albert Einstein College Of Medicine Of Yeshiva University Assay of transcription sites by multi-fluor fish
US20030017491A1 (en) * 2000-09-14 2003-01-23 Zuo-Rong Shi Chromogenic in situ hybridization methods, kits, and compositions
DE10061655A1 (de) * 2000-12-11 2002-06-20 Vermicon Ag In situ-Hybridisierungs-Anordnung zum spezifischen Nachweis von Mikroorganismen
US6696271B2 (en) 2001-08-23 2004-02-24 The Regents Of The University Of California Frozen tissue microarray technology for analysis of RNA, DNA, and proteins
US6924102B2 (en) * 2001-08-24 2005-08-02 Huynh Mai Thi Nguyen Utilization of nucleotide probes for the measurement of specific mRNA for the molecular diagnosis of autosomal recessive spinal muscular atrophy
US6580056B1 (en) * 2001-09-21 2003-06-17 Biocare Medical Biological specimen heating device and quality control method for immunohistochemistry heat retrieval procedures
US6995020B2 (en) * 2003-07-21 2006-02-07 Aureon Laboratories, Inc. Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization

Also Published As

Publication number Publication date
US6995020B2 (en) 2006-02-07
US7326575B2 (en) 2008-02-05
EP1689883B1 (de) 2009-10-21
EP1689883A2 (de) 2006-08-16
CA2532467C (en) 2011-03-22
US20050019779A1 (en) 2005-01-27
EP1689883A4 (de) 2007-10-10
ATE446383T1 (de) 2009-11-15
AU2004260105A1 (en) 2005-02-03
US20060141502A1 (en) 2006-06-29
WO2005010203A3 (en) 2005-11-10
CA2532467A1 (en) 2005-02-03
WO2005010203A2 (en) 2005-02-03

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee