DE602004018527D1 - FURANDERIVATES AS EP4 RECEPTOR ANTAGONISTS - Google Patents

FURANDERIVATES AS EP4 RECEPTOR ANTAGONISTS

Info

Publication number
DE602004018527D1
DE602004018527D1 DE602004018527T DE602004018527T DE602004018527D1 DE 602004018527 D1 DE602004018527 D1 DE 602004018527D1 DE 602004018527 T DE602004018527 T DE 602004018527T DE 602004018527 T DE602004018527 T DE 602004018527T DE 602004018527 D1 DE602004018527 D1 DE 602004018527D1
Authority
DE
Germany
Prior art keywords
furanderivates
receptor antagonists
antagonists
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004018527T
Other languages
German (de)
Inventor
David Edward Clark
Neil Victor Harris
Garry Fenton
George Hynd
Keith Alfred James Stuttle
Jonathan Mark Sutton
Alexander William Oxford
Richard Jon Davis
Robert Alexander Coleman
Kenneth Lyle Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asterand UK Acquisition Ltd
Original Assignee
Asterand UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0324269.0A external-priority patent/GB0324269D0/en
Application filed by Asterand UK Ltd filed Critical Asterand UK Ltd
Publication of DE602004018527D1 publication Critical patent/DE602004018527D1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE602004018527T 2003-10-16 2004-10-15 FURANDERIVATES AS EP4 RECEPTOR ANTAGONISTS Active DE602004018527D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0324269.0A GB0324269D0 (en) 2003-10-16 2003-10-16 EP4 receptor antagonists
US51220003P 2003-10-20 2003-10-20
PCT/GB2004/004392 WO2005037812A1 (en) 2003-10-16 2004-10-15 Furan derivatives as ep4 receptor antagonists

Publications (1)

Publication Number Publication Date
DE602004018527D1 true DE602004018527D1 (en) 2009-01-29

Family

ID=34466432

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004018527T Active DE602004018527D1 (en) 2003-10-16 2004-10-15 FURANDERIVATES AS EP4 RECEPTOR ANTAGONISTS

Country Status (3)

Country Link
KR (1) KR20060097028A (en)
DE (1) DE602004018527D1 (en)
NO (1) NO20062187L (en)

Also Published As

Publication number Publication date
NO20062187L (en) 2006-07-07
KR20060097028A (en) 2006-09-13

Similar Documents

Publication Publication Date Title
DK1638969T3 (en) CGRP receptor antagonists
DK1682142T3 (en) M3-muscarinic acetylcholine receptor antagonists
DK1711465T3 (en) Hydroisoindoline tachykinic receptor antagonists
ATE394391T1 (en) INDOLE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS
ATE384053T1 (en) TRIAZOLE DERIVATIVES AS TACHYKINE RECEPTOR ANTAGONISTS
DK1677795T3 (en) Muscarine acetylcholine receptor antagonists
NO20051871D0 (en) Opioid receptor antagonists
ATE413874T1 (en) NEW THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR ANTAGONISTS
ATE518834T1 (en) 2,3,4,9-TETRAHYDRO-1H-CARBAZOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS
ATE523195T1 (en) NEW THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR ANTAGONISTS
DE602005009355D1 (en) DISABLED HIMBACINANALOGA AS THROMBIN RECEPTOR ANTAGONISTS
DK1951660T3 (en) Histamine 3 receptor antagonists
DE60331751D1 (en) N-SUBSTITUTED 2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS
IS8501A (en) Azate cyclic heterocycles as cannabinonide receptor antagonists
NL2000241A1 (en) Carboxamide derivatives as muscarinic receptor antagonists.
DK1973886T3 (en) PROKINETICIN-1 Receptor Antagonists
ATE429428T1 (en) INDANDERIVATES AS ANTAGONISTS OF THE MCH RECEPTOR
ATE462688T1 (en) DIARYLSULFONES AS 5-HT2A ANTAGONISTS
DE602004004278D1 (en) 4-CYCLOALKYLAMINOPYRAZOLOPYRIMIDINE AS NMDA / NR2B ANTAGONISTS
DE60316411D1 (en) THIAZONE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS
DE602006003666D1 (en) INDOL-3-YLCARBONYLPIPERIDINBENZIMIDAZOLE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS
ATE403651T1 (en) 3-FLUORO-PIPERIDINE AS NMDA/NR2B ANTAGONISTS
ATE377008T1 (en) IMIDAZOLE DERIVATIVES AS GLUTAMA RECEPTOR ANTAGONISTS
ATE488519T1 (en) INDOL-3-YLCARBONYLAZASPIRO DERIVATIVES AS VASOPRESSIN RECEPTOR ANTAGONISTS
ATE425161T1 (en) MERCAPTOIMIDAZOLE AS CCR2 RECEPTOR ANTAGONISTS

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R081 Change of applicant/patentee

Ref document number: 1673360

Country of ref document: EP

Owner name: ASTERAND UK ACQUISITION LIMITED, GB

Free format text: FORMER OWNER: ASTERAND UK LTD., ROYSTON, GB

Effective date: 20121011

R082 Change of representative

Ref document number: 1673360

Country of ref document: EP

Representative=s name: LEINWEBER & ZIMMERMANN, DE

Effective date: 20121011