DE60105435D1 - PROCESS FOR THE PREPARATION OF BETA-CARKINE - Google Patents

PROCESS FOR THE PREPARATION OF BETA-CARKINE

Info

Publication number
DE60105435D1
DE60105435D1 DE60105435T DE60105435T DE60105435D1 DE 60105435 D1 DE60105435 D1 DE 60105435D1 DE 60105435 T DE60105435 T DE 60105435T DE 60105435 T DE60105435 T DE 60105435T DE 60105435 D1 DE60105435 D1 DE 60105435D1
Authority
DE
Germany
Prior art keywords
beta
carotene
carkine
preparation
blakeslea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60105435T
Other languages
German (de)
Other versions
DE60105435T2 (en
Inventor
Perez Javier Costa
Castro Antonio Estrella
Rodriguez Ana Teresa Marcos
De Prado J Emiliano Gonzalez
Cezon Enrique E Peiro
De La Vieja Alfonso Collados
Morales Manuel Esteban
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitatene SA
Original Assignee
Vitatene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitatene SA filed Critical Vitatene SA
Application granted granted Critical
Publication of DE60105435D1 publication Critical patent/DE60105435D1/en
Publication of DE60105435T2 publication Critical patent/DE60105435T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/931—Mucor

Abstract

A process for obtaining beta -carotene. The present invention relates to a new process for the production of beta -carotene from submerged cultures of mucor fungi such as Blakeslea, Choanephora or Phycomyces by means of addition to the culture medium of lecithin in conjunction with pH control once fermentation has started, a process that includes a step of recovery of beta -carotene that allows a simplification in the process, an optimisation of the yield, along with an increase in the purification of the product.
DE60105435T 2000-07-19 2001-07-18 PROCESS FOR THE PREPARATION OF BETA-CARKINE Expired - Lifetime DE60105435T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200001792A ES2168971B1 (en) 2000-07-19 2000-07-19 BETA-CAROTENE PRODUCTION PROCEDURE.
ES200001792 2000-07-19
PCT/ES2001/000284 WO2002010429A1 (en) 2000-07-19 2001-07-18 Method for the production of beta-carotene

Publications (2)

Publication Number Publication Date
DE60105435D1 true DE60105435D1 (en) 2004-10-14
DE60105435T2 DE60105435T2 (en) 2005-09-22

Family

ID=8494321

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105435T Expired - Lifetime DE60105435T2 (en) 2000-07-19 2001-07-18 PROCESS FOR THE PREPARATION OF BETA-CARKINE

Country Status (10)

Country Link
US (1) US8859228B2 (en)
EP (1) EP1306444B1 (en)
JP (1) JP4287142B2 (en)
AT (1) ATE275635T1 (en)
AU (1) AU2001272562A1 (en)
DE (1) DE60105435T2 (en)
ES (2) ES2168971B1 (en)
PT (1) PT1306444E (en)
TR (1) TR200402687T4 (en)
WO (1) WO2002010429A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2195766B1 (en) * 2002-01-29 2005-04-01 Antibioticos, S.A.U. BETA-CAROTENE PRODUCTION PROCEDURE FOR FERMENTATION IN MIXED CULTURE USING BLAPESLEA TRISPORA (+) 4 (-).
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
CA2658483A1 (en) 2006-07-21 2008-01-24 Xyleco, Inc. Conversion systems for biomass
EP2078092A2 (en) 2006-09-28 2009-07-15 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US20100145116A1 (en) 2007-03-08 2010-06-10 Frederik Van Keulen Production of High-Purity Carotenoids by Fermenting Selected Bacterial Strains
JPWO2011013707A1 (en) 2009-07-29 2013-01-10 味の素株式会社 Method for producing L-amino acid
DK2571996T3 (en) 2010-05-17 2017-05-08 Dynadis Biotehc (India) Private Ltd PROCEDURE FOR PREPARING BETA CAROTH AND HIGH-PURITY LYCOPEN CRYSTALS FROM FUNGI BIOMASS
CN102787158B (en) 2011-05-20 2015-01-21 浙江医药股份有限公司新昌制药厂 Method for producing natural beta-carotene by fermentation and application
DE102014208876B4 (en) * 2014-05-12 2018-10-31 Jäckering Research GmbH Process for the preparation of carotenoids by submerged fermentation with mixed cultures of (+) and (-) strains of the fungus Blakeslea trispora
CN104557648A (en) * 2014-12-23 2015-04-29 嘉必优生物工程（武汉）有限公司 Method for preparing beta-carotene
CN109280685B (en) * 2017-07-21 2021-11-23 浙江医药股份有限公司新昌制药厂 Method for producing natural carotenoid by increasing dissolved oxygen in fermentation process of natural carotenoid
CN114127259A (en) 2019-08-01 2022-03-01 帝斯曼知识产权资产管理有限公司 Beta-carotene fermentation method
WO2022090547A1 (en) 2020-10-30 2022-05-05 Dsm Ip Assets B.V. Production of carotenoids by fermentation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2959521A (en) * 1959-01-12 1960-11-08 Grain Processing Corp Process for preparing beta-carotene
US3268606A (en) * 1963-09-27 1966-08-23 Upjohn Co Beta-carotene process
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
EP0410236B1 (en) * 1989-07-25 1993-10-27 F. Hoffmann-La Roche Ag Process for the production of carotinoid preparations
WO1991018108A1 (en) * 1990-05-15 1991-11-28 Zeagen, Inc. A high productivity, continuous fermentation process for carotenoid-producing microorganisms
IL104736A0 (en) * 1992-03-27 1993-06-10 Zeagen Inc Method for producing beta-carotene using a fungal mated culture
US5466599A (en) * 1993-04-19 1995-11-14 Universal Foods Corporation Astaxanthin over-producing strains of phaffia rhodozyma
DE4429506B4 (en) * 1994-08-19 2007-09-13 Degussa Gmbh Process for the extraction of natural carotenoid dyes
DE19531254A1 (en) * 1995-08-25 1997-02-27 Sueddeutsche Kalkstickstoff Process for the extraction of carotene dyes from solid natural substances
JP2000515742A (en) * 1996-07-19 2000-11-28 ギスト ブロカデス ベスローテン フェンノートシャップ Method for recovering crystalline β-carotene from natural raw materials
ES2337530T3 (en) * 1997-05-02 2010-04-26 Dsm Ip Assets B.V. INSULATION OF CAROTENOID CRYSTALS FROM MICROBIAL BIOMASS.
US6048846A (en) * 1998-02-26 2000-04-11 Cochran; Timothy M. Compositions used in human treatment
US6309677B1 (en) * 1998-03-24 2001-10-30 Amway Corporation Multi-carotenoid product
US6262284B1 (en) * 1998-10-21 2001-07-17 University Of Maryland Process for extraction and purification of lutein, zeaxanthin and rare carotenoids from marigold flowers and plants
DE60008299T2 (en) * 2000-07-13 2004-11-25 Vitatene, S.A. Process for the preparation of a water-dispersible carotenoid-containing formulation

Also Published As

Publication number Publication date
DE60105435T2 (en) 2005-09-22
US20040067550A1 (en) 2004-04-08
ES2168971A1 (en) 2002-06-16
PT1306444E (en) 2004-11-30
EP1306444A1 (en) 2003-05-02
JP4287142B2 (en) 2009-07-01
JP2004504853A (en) 2004-02-19
ATE275635T1 (en) 2004-09-15
EP1306444B1 (en) 2004-09-08
WO2002010429A1 (en) 2002-02-07
TR200402687T4 (en) 2004-11-22
ES2223894T3 (en) 2005-03-01
AU2001272562A1 (en) 2002-02-13
ES2168971B1 (en) 2003-11-01
US8859228B2 (en) 2014-10-14

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