DE60100879D1 - Helicobacter felis vaccine - Google Patents
Helicobacter felis vaccineInfo
- Publication number
- DE60100879D1 DE60100879D1 DE60100879T DE60100879T DE60100879D1 DE 60100879 D1 DE60100879 D1 DE 60100879D1 DE 60100879 T DE60100879 T DE 60100879T DE 60100879 T DE60100879 T DE 60100879T DE 60100879 D1 DE60100879 D1 DE 60100879D1
- Authority
- DE
- Germany
- Prior art keywords
- subunit polypeptides
- helicobacter felis
- nucleic acid
- acid sequences
- vaccines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000590017 Helicobacter felis Species 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 150000007523 nucleic acids Chemical group 0.000 abstract 4
- 108020004414 DNA Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 108010046334 Urease Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
The present invention relates to novel Helicobacter felis urease subunit polypeptides and to nucleic acid sequences encoding these subunit polypeptides, to DNA fragments and recombinant DNA molecules comprising the nucleic acid sequences encoding these subunit polypeptides, to live recombinant carriers and to host cells comprising nucleic acid sequences encoding these subunit polypeptides. Also, the invention relates to the subunit polypeptides for use in vaccines and the use in the manufacturing thereof, to vaccines comprising said subunit polypeptides and to methods for the preparation of such vaccines. Furthermore, the invention relates to diagnostic methods for the detection of Helicobacter felis specific nucleic acid sequences, Helicobacter felis antigenic material and to antibodies against Helicobacter felis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00202565 | 2000-07-17 | ||
EP00202565 | 2000-07-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60100879D1 true DE60100879D1 (en) | 2003-11-06 |
DE60100879T2 DE60100879T2 (en) | 2004-05-19 |
Family
ID=8171823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60100879T Expired - Fee Related DE60100879T2 (en) | 2000-07-17 | 2001-07-11 | Helicobacter felis vaccine |
Country Status (10)
Country | Link |
---|---|
US (1) | US7514547B2 (en) |
EP (1) | EP1176192B1 (en) |
JP (1) | JP2002355054A (en) |
AT (1) | ATE251215T1 (en) |
AU (1) | AU782172B2 (en) |
CA (1) | CA2351110A1 (en) |
DE (1) | DE60100879T2 (en) |
DK (1) | DK1176192T3 (en) |
ES (1) | ES2208519T3 (en) |
PT (1) | PT1176192E (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8029777B2 (en) | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
JP2008509168A (en) * | 2004-08-13 | 2008-03-27 | マーシャル,バリー,ジェー. | Bacteria delivery system |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6290962B1 (en) * | 1992-11-03 | 2001-09-18 | Oravax, Inc. | Urease-based vaccine and treatment for helicobacter infection |
US6258359B1 (en) * | 1993-05-19 | 2001-07-10 | Institut Pasteur | Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides |
WO1995014093A1 (en) * | 1993-05-19 | 1995-05-26 | Institut Pasteur | Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions and nucleic acid sequences encoding said polypeptides |
US5610060A (en) * | 1994-06-24 | 1997-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Isolated Helicobacter hepaticus |
WO1996033220A1 (en) * | 1995-04-21 | 1996-10-24 | Csl Limited | Protective helicobacter antigens |
JP3007037B2 (en) * | 1995-07-19 | 2000-02-07 | 秀実 高橋 | Helicobacter pylori urease protein-derived artificial antigen and antibody induced by the artificial antigen |
GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
JP3430853B2 (en) * | 1997-04-11 | 2003-07-28 | 株式会社ゲン・コーポレーション | Preventive and therapeutic agents for gastritis, gastric ulcer and duodenal ulcer |
US20030158396A1 (en) * | 1997-07-29 | 2003-08-21 | Harold Kleanthous | Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome |
US5985631A (en) * | 1997-09-12 | 1999-11-16 | Oravax-Merieux Co. | Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease |
EP1278768B1 (en) * | 2000-04-27 | 2006-11-15 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for identifying helicobacter antigens |
-
2001
- 2001-07-03 CA CA002351110A patent/CA2351110A1/en not_active Abandoned
- 2001-07-11 PT PT01202666T patent/PT1176192E/en unknown
- 2001-07-11 AU AU54321/01A patent/AU782172B2/en not_active Ceased
- 2001-07-11 EP EP01202666A patent/EP1176192B1/en not_active Expired - Lifetime
- 2001-07-11 DE DE60100879T patent/DE60100879T2/en not_active Expired - Fee Related
- 2001-07-11 ES ES01202666T patent/ES2208519T3/en not_active Expired - Lifetime
- 2001-07-11 DK DK01202666T patent/DK1176192T3/en active
- 2001-07-11 AT AT01202666T patent/ATE251215T1/en not_active IP Right Cessation
- 2001-07-13 US US09/904,994 patent/US7514547B2/en not_active Expired - Fee Related
- 2001-07-16 JP JP2001214711A patent/JP2002355054A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2002355054A (en) | 2002-12-10 |
ATE251215T1 (en) | 2003-10-15 |
DK1176192T3 (en) | 2004-02-02 |
EP1176192A2 (en) | 2002-01-30 |
DE60100879T2 (en) | 2004-05-19 |
US7514547B2 (en) | 2009-04-07 |
CA2351110A1 (en) | 2002-01-17 |
ES2208519T3 (en) | 2004-06-16 |
US20040005325A1 (en) | 2004-01-08 |
AU5432101A (en) | 2002-01-24 |
EP1176192A3 (en) | 2002-02-06 |
PT1176192E (en) | 2004-01-30 |
AU782172B2 (en) | 2005-07-07 |
EP1176192B1 (en) | 2003-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: INTERVET INTERNATIONAL B. V., AN BOXMEER, NL |
|
8339 | Ceased/non-payment of the annual fee |