DE60028005D1 - PROCESS FOR THE QUALITY CONTROL AND STANDARDIZATION OF MEDICAL PLANT PRODUCTS - Google Patents

PROCESS FOR THE QUALITY CONTROL AND STANDARDIZATION OF MEDICAL PLANT PRODUCTS

Info

Publication number
DE60028005D1
DE60028005D1 DE60028005T DE60028005T DE60028005D1 DE 60028005 D1 DE60028005 D1 DE 60028005D1 DE 60028005 T DE60028005 T DE 60028005T DE 60028005 T DE60028005 T DE 60028005T DE 60028005 D1 DE60028005 D1 DE 60028005D1
Authority
DE
Germany
Prior art keywords
plant material
medicinal plant
standard
standardization
quality control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60028005T
Other languages
German (de)
Other versions
DE60028005T2 (en
Inventor
John Hylands
Jeremy Kirk Nicholson
Elaine Claire Holmes
Michael John Dunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Natural Products PLC
Original Assignee
Oxford Natural Products PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9903011.6A external-priority patent/GB9903011D0/en
Priority claimed from GBGB9919573.7A external-priority patent/GB9919573D0/en
Priority claimed from GBGB9928541.3A external-priority patent/GB9928541D0/en
Application filed by Oxford Natural Products PLC filed Critical Oxford Natural Products PLC
Application granted granted Critical
Publication of DE60028005D1 publication Critical patent/DE60028005D1/en
Publication of DE60028005T2 publication Critical patent/DE60028005T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5097—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving plant cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Control Of Non-Electrical Variables (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrotherapy Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Paper (AREA)

Abstract

A process for establishing a standard specification for a medicinal plant material comprises: (i) preparing a test solution or test extract of a sample of the medicinal plant material which is known to possess the or each property required for the standard; (ii) submitting the said solution or extract to two or more analytical methods including (a) a combination of NMR spectroscopy and a computer-based pattern recognition technique, and (b) one or more biological profiling techniques; (iii) obtaining results from the analytical methods used in step (ii); and (iv) establishing a standard specification for the said plant material on the basis of the results obtained in step (iii). Candidate samples of the medicinal plant material may subsequently be tested for compliance with the standard. They can be accepted or rejected depending on whether they give analytical results which fall within or outside either part or all of the specification established in step (iv). This approach to standardization and quality control is particularly applicable to mixtures of medicinal plant materials.
DE60028005T 1999-02-10 2000-02-10 PROCESS FOR THE QUALITY CONTROL AND STANDARDIZATION OF MEDICAL PLANT PRODUCTS Expired - Lifetime DE60028005T2 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB9903011 1999-02-10
GBGB9903011.6A GB9903011D0 (en) 1999-02-10 1999-02-10 Process for quality control of medicinal plant products
US12059199P 1999-02-18 1999-02-18
US120591P 1999-02-18
GB9919573 1999-08-18
GBGB9919573.7A GB9919573D0 (en) 1999-08-18 1999-08-18 Process for quality control of medicinal plant products
US14946899P 1999-08-19 1999-08-19
US149468P 1999-08-19
US16838299P 1999-12-02 1999-12-02
GB9928541 1999-12-02
GBGB9928541.3A GB9928541D0 (en) 1999-12-02 1999-12-02 Process for quality control of medicinal plant products
US168382P 1999-12-02
PCT/GB2000/000428 WO2000047992A1 (en) 1999-02-10 2000-02-10 Process for quality control and standardisation of medicinal plant products

Publications (2)

Publication Number Publication Date
DE60028005D1 true DE60028005D1 (en) 2006-06-22
DE60028005T2 DE60028005T2 (en) 2006-12-14

Family

ID=27547332

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60028005T Expired - Lifetime DE60028005T2 (en) 1999-02-10 2000-02-10 PROCESS FOR THE QUALITY CONTROL AND STANDARDIZATION OF MEDICAL PLANT PRODUCTS

Country Status (17)

Country Link
US (1) US6806090B1 (en)
EP (1) EP1151292B1 (en)
JP (1) JP2002536664A (en)
KR (1) KR20010108196A (en)
CN (1) CN1201148C (en)
AT (1) ATE326695T1 (en)
AU (1) AU779104B2 (en)
BR (1) BR0008122A (en)
CA (1) CA2362058A1 (en)
DE (1) DE60028005T2 (en)
GB (1) GB2362953A (en)
HK (1) HK1046730A1 (en)
ID (1) ID30478A (en)
IL (1) IL144653A0 (en)
MX (1) MXPA01008030A (en)
NO (1) NO20013889L (en)
WO (1) WO2000047992A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375996B1 (en) * 2000-10-04 2002-04-23 Fmc Technologies, Inc. Method and system for processing pulp and juice in a juice finisher
FR2819591A1 (en) * 2001-01-12 2002-07-19 Agronomique Inst Nat Rech DISCRIMINATION PROCESS WITH LOCATION AND / OR IDENTIFICATION OF SITUATIONS OF BIOLOGICAL DISTURBANCES BY SPECTROMETRY AND RECOGNITION OF SHAPE
US6895340B2 (en) 2001-04-25 2005-05-17 Bristol-Myers Squibb Company Method of molecular structure recognition
IL160324A0 (en) * 2001-08-13 2004-07-25 Beyond Genomics Inc Method and system for profiling biological systems
NZ537571A (en) * 2002-07-17 2006-10-27 Univ California Methods and devices for analysis of sealed containers using nuclear magnetic resonance
BRPI0501384A8 (en) * 2005-04-15 2017-02-14 Cesar Abib Fernando statistical and analytical validation process for corneal endothelial cells
US20070009961A1 (en) * 2005-07-07 2007-01-11 Academia Sinica Identification of targeting component of herbal medicines from simplified HPLC spectrum using after flowing through immobilized receptor (AFTIR) method
JP4891874B2 (en) * 2007-09-07 2012-03-07 独立行政法人理化学研究所 Protein search method
WO2009036387A1 (en) * 2007-09-14 2009-03-19 Leung Albert Y System and method for assessing traditional medicines
KR100905414B1 (en) * 2008-06-25 2009-07-02 대한민국 Origin discrimination method of herbal medicine
US20120140981A1 (en) * 2008-07-17 2012-06-07 Chemlmage Corporation System and Method for Combining Visible and Hyperspectral Imaging with Pattern Recognition Techniques for Improved Detection of Threats
PL2419541T3 (en) * 2009-04-17 2017-09-29 President And Fellows Of Harvard College Quality control bioassays for nutriceutical and medicinal products
KR101128911B1 (en) 2009-12-17 2012-06-27 대한민국 Screening method for salinity tolerance in Panax ginseng C.A. Mayer
CN102393391B (en) * 2011-10-18 2013-02-27 深圳市药品检验所 Rapid measurement method of melatonin doped in Chinese patent medicine and healthcare food
CN103134827B (en) * 2013-01-29 2015-07-01 河南省科高植物天然产物开发工程技术有限公司 Method for identifying angled bittersweet seed medicinal materials
CN103149232A (en) * 2013-01-30 2013-06-12 河南省科高植物天然产物开发工程技术有限公司 Method for identifying pyrethrum derivatives
US9632069B2 (en) 2014-02-05 2017-04-25 Vyripharm Llc Integrated systems and methods of evaluating cannabis and cannabinoid products for public safety, quality control and quality assurance purposes
CN104122287B (en) * 2014-08-01 2016-08-17 山西大学 A kind of wild Radix Astragali and the discrimination method of the cultivation Radix Astragali
JP7038992B2 (en) * 2017-09-29 2022-03-22 丸善製薬株式会社 How to identify licorice plant species

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2530026A1 (en) 1982-07-09 1984-01-13 Bengsch Eberhard PROCESS FOR IDENTIFYING AND DETERMINING BIOLOGICAL AND / OR TECHNO-SYNTHETIC ORIGINS OF ORGANIC SUBSTANCES
JPH07119720B2 (en) * 1989-02-23 1995-12-20 鐘紡株式会社 Method of selecting components from standard data in composition analysis of mixtures
JPH07119721B2 (en) * 1989-04-19 1995-12-20 鐘紡株式会社 Method for qualitatively quantifying composition components of mixture and method for preparing standard data used in the method
FR2732112B1 (en) * 1994-12-16 1997-06-20 Conseil Interprofessionnel Du METHOD FOR IDENTIFYING PLANT SPECIES AND THEIR HYBRIDS

Also Published As

Publication number Publication date
US6806090B1 (en) 2004-10-19
JP2002536664A (en) 2002-10-29
CN1201148C (en) 2005-05-11
GB0121376D0 (en) 2001-10-24
AU779104B2 (en) 2005-01-06
IL144653A0 (en) 2002-05-23
DE60028005T2 (en) 2006-12-14
ATE326695T1 (en) 2006-06-15
AU2450800A (en) 2000-08-29
EP1151292A1 (en) 2001-11-07
MXPA01008030A (en) 2003-06-24
HK1046730A1 (en) 2003-01-24
CN1357106A (en) 2002-07-03
KR20010108196A (en) 2001-12-07
GB2362953A (en) 2001-12-05
NO20013889D0 (en) 2001-08-09
BR0008122A (en) 2001-11-13
CA2362058A1 (en) 2000-08-17
EP1151292B1 (en) 2006-05-17
WO2000047992A1 (en) 2000-08-17
NO20013889L (en) 2001-10-03
ID30478A (en) 2001-12-13

Similar Documents

Publication Publication Date Title
DE60028005D1 (en) PROCESS FOR THE QUALITY CONTROL AND STANDARDIZATION OF MEDICAL PLANT PRODUCTS
Verdonck et al. Breast cancer and melanoma cell line identification by FTIR imaging after formalin-fixation and paraffin-embedding
DE829065T1 (en) METHOD AND APPARATUS FOR DETERMINING THE PREPARATION QUALITY OF SLIDES AND SAMPLES
DE502004008216D1 (en) APPARATUS AND METHOD FOR THE SIMULTANEOUS PROCESSING OF BLOOD GROUP DETERMINATION, SERUM COMPOST AND ANTIBODY TESTING TEST
DE69228539D1 (en) METHOD FOR CLASSIFYING ANALYTES BY MEANS OF CONCENTRATION ("SC") PROFILES
ATE98773T1 (en) METHODS OF OPTICAL ANALYSIS.
CN108195794B (en) A kind of method that near infrared ray pheretima extracts Lumbrokinase potency in intermediate
ATE489635T1 (en) APPARATUS, METHOD AND USE FOR TREATING SAMPLES
EP2299259B1 (en) Method and use of an apparatus for In-Vitro-Analysis of Biological Cells and/or Microorganisms
MY124966A (en) Process for quality control and standardisation of medicinal plant products
Khanmohammadi et al. Chemometrics assisted investigation of variations in infrared spectra of blood samples obtained from women with breast cancer: a new approach for cancer diagnosis
ES2084628T3 (en) ENZYMATIC METHOD TO DETERMINE THE CONCENTRATIONS OF THE ANALYZED PRODUCT.
DE69614374D1 (en) METHOD FOR SPECTRAL ANALYSIS OF INHOMOGENIC SAMPLES
AU2021201A (en) Apparatus and method for measuring a property of a liquid
CN206038516U (en) High flux real -time detection system is united to optoacoustic
US8552383B2 (en) Methods and systems for in-vitro analysis of biological cells and/or microorganisms
DE102004023519A1 (en) Equipment for automatic measurement of chemicals based on immunochemical methods, includes pipetting apparatus with reader and vibrator under randomizing software control
ATE274182T1 (en) APPARATUS AND METHOD FOR SUPERCRITICAL LIQUID EXTRACTION
WO2002076282A3 (en) Method for quantitative analysis of blood vessel structure
CN106706519B (en) Method for simultaneously and rapidly qualitatively analyzing activities of two transaminases in serum based on spectrometry
KR20230126523A (en) Method and device for quantification of car protein in cell therapy products using raman spectroscopic analysis
CN113189038A (en) Red sage root tablet intermediate content detection method based on near-infrared diffuse reflection spectrum
CN112345488A (en) Method for measuring uronic acid and protein content and molecular weight in hyaluronic acid
WO2000061784A3 (en) Non-invasive composition analysis
Chang et al. A TETRAZOLIUM-BASED (MTT) ASSAY FOR MEASURING

Legal Events

Date Code Title Description
8364 No opposition during term of opposition