DE60024451D1 - Bindung mehrerer zinkfinger transkriptionsfaktoren an nukleinsäuren - Google Patents
Bindung mehrerer zinkfinger transkriptionsfaktoren an nukleinsäurenInfo
- Publication number
- DE60024451D1 DE60024451D1 DE60024451T DE60024451T DE60024451D1 DE 60024451 D1 DE60024451 D1 DE 60024451D1 DE 60024451 T DE60024451 T DE 60024451T DE 60024451 T DE60024451 T DE 60024451T DE 60024451 D1 DE60024451 D1 DE 60024451D1
- Authority
- DE
- Germany
- Prior art keywords
- seq
- cacct
- separated
- aggtg
- transcription factors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108091023040 Transcription factor Proteins 0.000 title abstract 4
- 102000040945 Transcription factor Human genes 0.000 title abstract 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000011701 zinc Substances 0.000 title abstract 2
- 229910052725 zinc Inorganic materials 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 101000926140 Homo sapiens Gem-associated protein 2 Proteins 0.000 abstract 2
- 101000716750 Homo sapiens Protein SCAF11 Proteins 0.000 abstract 2
- 101000723833 Homo sapiens Zinc finger E-box-binding homeobox 2 Proteins 0.000 abstract 2
- 206010027476 Metastases Diseases 0.000 abstract 2
- 102100020876 Protein SCAF11 Human genes 0.000 abstract 2
- 102000038627 Zinc finger transcription factors Human genes 0.000 abstract 2
- 108091007916 Zinc finger transcription factors Proteins 0.000 abstract 2
- 230000009401 metastasis Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000000905 Cadherin Human genes 0.000 abstract 1
- 108050007957 Cadherin Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 206010064390 Tumour invasion Diseases 0.000 abstract 1
- 230000009400 cancer invasion Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003828 downregulation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99202068 | 1999-06-25 | ||
EP99202068 | 1999-06-25 | ||
PCT/EP2000/005582 WO2001000864A2 (en) | 1999-06-25 | 2000-06-09 | Nucleic acid binding of multi-zinc finger transcription factors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60024451D1 true DE60024451D1 (de) | 2006-01-05 |
DE60024451T2 DE60024451T2 (de) | 2006-08-17 |
Family
ID=8240367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60024451T Expired - Fee Related DE60024451T2 (de) | 1999-06-25 | 2000-06-09 | Bindung mehrerer zinkfinger transkriptionsfaktoren an nukleinsäuren |
Country Status (8)
Country | Link |
---|---|
US (2) | US20030044809A1 (de) |
EP (1) | EP1192268B1 (de) |
JP (1) | JP2003523732A (de) |
AT (1) | ATE311471T1 (de) |
AU (1) | AU772452B2 (de) |
CA (1) | CA2370687A1 (de) |
DE (1) | DE60024451T2 (de) |
WO (1) | WO2001000864A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE311471T1 (de) | 1999-06-25 | 2005-12-15 | Vlaams Interuniv Inst Biotech | Bindung mehrerer zinkfinger transkriptionsfaktoren an nukleinsäuren |
US7361635B2 (en) | 2002-08-29 | 2008-04-22 | Sangamo Biosciences, Inc. | Simultaneous modulation of multiple genes |
WO2004086038A2 (en) * | 2003-03-28 | 2004-10-07 | Institut Curie | A method for screening compounds having the capacity to control tumor cell invasion or metastasis using constitutively active akt |
US20090177191A1 (en) * | 2007-12-11 | 2009-07-09 | Brown Joe D | Laser surgery methods and apparatus |
WO2009106578A1 (en) * | 2008-02-27 | 2009-09-03 | Vib Vzw | Use of sip1 as determinant of breast cancer stemness |
JPWO2016121715A1 (ja) * | 2015-01-26 | 2017-11-02 | 国立大学法人名古屋大学 | 肺がん患者の予後を評価するための情報を提供する方法、肺がん患者の予後予測方法、内部標準、抗体、肺がん患者の予後予測装置、予後予測装置のプログラム及び記録媒体 |
CN107083427B (zh) * | 2016-04-01 | 2021-07-30 | 广州市基准医疗有限责任公司 | Dna连接酶介导的dna扩增技术 |
US11739370B1 (en) | 2020-01-10 | 2023-08-29 | Gordian Biotechnology, Inc. | Methods and compositions for in vivo screening of therapeutics through spatial transcriptomics |
EP4330406A1 (de) * | 2021-04-26 | 2024-03-06 | Gordian Biotechnology, Inc. | Zusammensetzungen und verfahren zum in-vivo-screening von therapeutika mit einzelkernsequenzierung |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE312198T1 (de) * | 1993-04-05 | 2005-12-15 | Univ Utah Res Found | Diagnose und behandlung von supravalvular aortic stenosis |
FR2710075B1 (fr) * | 1993-09-15 | 1995-10-27 | Bio Merieux | Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal. |
US5851759A (en) * | 1996-04-19 | 1998-12-22 | Chiron Corporation | Heteroduplex tracking assay (HTA) for genotyping HCV |
AU8623798A (en) * | 1997-06-02 | 1998-12-21 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Smad-interacting polypeptides and their use |
US6537751B1 (en) * | 1998-04-21 | 2003-03-25 | Genset S.A. | Biallelic markers for use in constructing a high density disequilibrium map of the human genome |
ATE311471T1 (de) | 1999-06-25 | 2005-12-15 | Vlaams Interuniv Inst Biotech | Bindung mehrerer zinkfinger transkriptionsfaktoren an nukleinsäuren |
-
2000
- 2000-06-09 AT AT00942090T patent/ATE311471T1/de not_active IP Right Cessation
- 2000-06-09 JP JP2001506856A patent/JP2003523732A/ja not_active Withdrawn
- 2000-06-09 WO PCT/EP2000/005582 patent/WO2001000864A2/en active IP Right Grant
- 2000-06-09 AU AU56832/00A patent/AU772452B2/en not_active Ceased
- 2000-06-09 DE DE60024451T patent/DE60024451T2/de not_active Expired - Fee Related
- 2000-06-09 CA CA002370687A patent/CA2370687A1/en not_active Abandoned
- 2000-06-09 EP EP00942090A patent/EP1192268B1/de not_active Expired - Lifetime
-
2001
- 2001-12-21 US US10/028,396 patent/US20030044809A1/en not_active Abandoned
-
2005
- 2005-08-03 US US11/196,670 patent/US7435806B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030044809A1 (en) | 2003-03-06 |
US20050272090A1 (en) | 2005-12-08 |
DE60024451T2 (de) | 2006-08-17 |
EP1192268A2 (de) | 2002-04-03 |
ATE311471T1 (de) | 2005-12-15 |
WO2001000864A3 (en) | 2001-11-29 |
US7435806B2 (en) | 2008-10-14 |
CA2370687A1 (en) | 2001-01-04 |
JP2003523732A (ja) | 2003-08-12 |
EP1192268B1 (de) | 2005-11-30 |
WO2001000864A2 (en) | 2001-01-04 |
AU5683200A (en) | 2001-01-31 |
AU772452B2 (en) | 2004-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |