DE60017074D1 - Implantable nuclear magnetic resonance spectrometer - Google Patents

Implantable nuclear magnetic resonance spectrometer

Info

Publication number
DE60017074D1
DE60017074D1 DE60017074T DE60017074T DE60017074D1 DE 60017074 D1 DE60017074 D1 DE 60017074D1 DE 60017074 T DE60017074 T DE 60017074T DE 60017074 T DE60017074 T DE 60017074T DE 60017074 D1 DE60017074 D1 DE 60017074D1
Authority
DE
Germany
Prior art keywords
magnetic resonance
nuclear magnetic
implant
resonance spectrometer
implantable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60017074T
Other languages
German (de)
Other versions
DE60017074T2 (en
Inventor
Alec Ginggen
Yanik Tardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medos International SARL
Original Assignee
Medos SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medos SARL filed Critical Medos SARL
Application granted granted Critical
Publication of DE60017074D1 publication Critical patent/DE60017074D1/en
Publication of DE60017074T2 publication Critical patent/DE60017074T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/302—Miniaturized sample handling arrangements for sampling small quantities, e.g. flow-through microfluidic NMR chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G01R33/307—Sample handling arrangements, e.g. sample cells, spinning mechanisms specially adapted for moving the sample relative to the MR system, e.g. spinning mechanisms, flow cells or means for positioning the sample inside a spectrometer

Abstract

Implantable nuclear magnetic resonance spectrometer contained in a housing comprising a permanent magnet arrangement (1,2,3,4) for generating a static magnetic field of suitable intensity and homogeneity for analysing a sample of fluid flowing into a catheter (6) traversing the implant. The implant further comprises an arrangement of electronic circuits (8,9) responsible for the excitation and detection of the nuclear magnetic resonance signal and at least one coil (7) to expose the fluid sample to the excitation signal and to collect the returned nuclear magnetic resonance signal. The implant also comprises the necessary RF circuits and an antenna (10) for communicating by conventional telemetry with an inductively coupled reader. <IMAGE>
DE60017074T 2000-03-06 2000-03-06 Implantable nuclear magnetic resonance spectrometer Expired - Lifetime DE60017074T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00104778A EP1132048B1 (en) 2000-03-06 2000-03-06 Implantable nuclear magnetic resonance spectrometer

Publications (2)

Publication Number Publication Date
DE60017074D1 true DE60017074D1 (en) 2005-02-03
DE60017074T2 DE60017074T2 (en) 2006-03-30

Family

ID=8168041

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60017074T Expired - Lifetime DE60017074T2 (en) 2000-03-06 2000-03-06 Implantable nuclear magnetic resonance spectrometer

Country Status (6)

Country Link
US (1) US6600945B2 (en)
EP (1) EP1132048B1 (en)
JP (1) JP4846112B2 (en)
AT (1) ATE285709T1 (en)
CA (1) CA2339325C (en)
DE (1) DE60017074T2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9694166B2 (en) 2002-03-26 2017-07-04 Medtronics Ps Medical, Inc. Method of draining cerebrospinal fluid
WO2003101534A1 (en) 2002-06-04 2003-12-11 Biophan Technologies, Inc. Nuclear magnetic resonance spectrometer assembly
US6925322B2 (en) * 2002-07-25 2005-08-02 Biophan Technologies, Inc. Optical MRI catheter system
US7781228B2 (en) * 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
JP5295769B2 (en) 2005-08-31 2013-09-18 ティツー・バイオシステムズ・インコーポレーテッド NMR apparatus for detecting analytes
US8368402B2 (en) * 2006-11-08 2013-02-05 T2 Biosystems, Inc. NMR systems for in vivo detection of analytes
US20110166614A1 (en) * 2007-12-21 2011-07-07 Hans Abrahamson Implantable analyte rf spectroscopy measuring system
EP2223133A1 (en) * 2007-12-21 2010-09-01 T2 Biosystems, Inc. Magnetic resonance system with implantable components and methods of use thereof
DE102010020152B4 (en) 2010-05-11 2013-10-24 Siemens Aktiengesellschaft Device with local coil arrangement and implantable device
US8729893B2 (en) * 2010-10-19 2014-05-20 Baker Hughes Incorporated Nuclear magnetic resonance 1H and 13C multiphase flow measurements, estimating phase selected flow rates from velocity distributions, volume fractions, and mean velocity
US20140194715A1 (en) * 2011-01-31 2014-07-10 Case Western Reserve University Glucose Analyzing Blood Examiner
US20120197107A1 (en) * 2011-01-31 2012-08-02 Case Western Reserve University Glucose analyzing blood examiner (gabe)
JP2015516826A (en) 2012-03-16 2015-06-18 バイタル センサーズ ホールディング カンパニー， インク．Ｖｉｔａｌ Ｓｅｎｓｏｒｓ Ｈｏｌｄｉｎｇ Ｃｏｍｐａｎｙ， Ｉｎｃ． Dielectric constant shielding
DE102018222446A1 (en) * 2018-12-20 2020-06-25 Robert Bosch Gmbh NMR measuring device and use of the NMR measuring device

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5072732A (en) * 1986-09-04 1991-12-17 Advanced Techtronics, Inc. NMR instrument for testing for fluid constituents
US5035231A (en) * 1987-04-27 1991-07-30 Olympus Optical Co., Ltd. Endoscope apparatus
JPH01299544A (en) * 1988-05-27 1989-12-04 Hitachi Ltd Mri photographing method
CH676164A5 (en) 1988-05-28 1990-12-14 Sc Techn Dipl Ing Peter A Neuk
US5127404A (en) 1990-01-22 1992-07-07 Medtronic, Inc. Telemetry format for implanted medical device
JPH067322A (en) * 1992-06-29 1994-01-18 Olympus Optical Co Ltd Mr endoscope device
US5572132A (en) * 1995-08-15 1996-11-05 Pulyer; Yuly M. MRI probe for external imaging
JPH1057339A (en) * 1996-08-19 1998-03-03 Ge Yokogawa Medical Syst Ltd Measuring mr signal, apparatus therefor and mr probe
DE19746735C2 (en) * 1997-10-13 2003-11-06 Simag Gmbh Systeme Und Instr F NMR imaging method for the display, position determination or functional control of a device inserted into an examination object and device for use in such a method
CA2391523C (en) * 1999-11-16 2012-08-21 Ernest Wollin Magnetic resonance analyzing flow meter and flow measuring method
ATE285708T1 (en) * 2000-03-06 2005-01-15 Medos Sa MINIMAL INVASIVE CATHETER PROBE FOR NUCLEAR RESONANCE SPECTROMETRY

Also Published As

Publication number Publication date
CA2339325A1 (en) 2001-09-06
EP1132048A1 (en) 2001-09-12
CA2339325C (en) 2009-06-30
US6600945B2 (en) 2003-07-29
US20010029331A1 (en) 2001-10-11
EP1132048B1 (en) 2004-12-29
JP2001269326A (en) 2001-10-02
DE60017074T2 (en) 2006-03-30
JP4846112B2 (en) 2011-12-28
ATE285709T1 (en) 2005-01-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MEDOS INTERNATIONAL S.A.R.L., LE LOCLE, CH