DE60015957D1 - Selen enthaltendes vorstufearzneimittel für krebstherapie - Google Patents

Selen enthaltendes vorstufearzneimittel für krebstherapie

Info

Publication number
DE60015957D1
DE60015957D1 DE60015957T DE60015957T DE60015957D1 DE 60015957 D1 DE60015957 D1 DE 60015957D1 DE 60015957 T DE60015957 T DE 60015957T DE 60015957 T DE60015957 T DE 60015957T DE 60015957 D1 DE60015957 D1 DE 60015957D1
Authority
DE
Germany
Prior art keywords
preliminary
cancer therapy
medicinal product
product
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60015957T
Other languages
English (en)
Other versions
DE60015957T2 (de
Inventor
Kenji Miki
Mingxu Xu
Yuying Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anticancer Inc
Original Assignee
Anticancer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anticancer Inc filed Critical Anticancer Inc
Application granted granted Critical
Publication of DE60015957D1 publication Critical patent/DE60015957D1/de
Publication of DE60015957T2 publication Critical patent/DE60015957T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60015957T 1999-05-11 2000-05-11 Selen enthaltendes vorstufearzneimittel für krebstherapie Expired - Lifetime DE60015957T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13367899P 1999-05-11 1999-05-11
US133678P 1999-05-11
PCT/US2000/012828 WO2000067762A2 (en) 1999-05-11 2000-05-11 Selenium-containing pro-drugs for cancer therapy

Publications (2)

Publication Number Publication Date
DE60015957D1 true DE60015957D1 (de) 2004-12-23
DE60015957T2 DE60015957T2 (de) 2005-11-03

Family

ID=22459797

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60015957T Expired - Lifetime DE60015957T2 (de) 1999-05-11 2000-05-11 Selen enthaltendes vorstufearzneimittel für krebstherapie

Country Status (7)

Country Link
US (2) US6653278B1 (de)
EP (1) EP1176968B1 (de)
JP (1) JP5072142B2 (de)
AU (1) AU784612B2 (de)
CA (1) CA2372992C (de)
DE (1) DE60015957T2 (de)
WO (1) WO2000067762A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT412447B (de) * 2002-11-27 2005-03-25 C Y L Handelsges M B H Mittel mit zerstörender wirkung auf maligne tumore sowie verfahren zu seiner herstellung
GB2417685B (en) * 2003-05-13 2007-12-19 Health Research Inc Method for augmenting the antitumor activity of anti-cancer agents
US20110002978A1 (en) * 2003-06-17 2011-01-06 Harrison Roger G Enzyme prodrug cancer therapy selectively targeted to tumor cells or tumor vasculature and methods of production and use thereof
US7534818B1 (en) 2003-09-15 2009-05-19 Health Research, Inc. Method of reducing alopecia and bladder toxicity of cyclophosphamide
FR2873376B1 (fr) * 2004-07-23 2006-11-24 Tetrahedron Sas Nouveaux seleno-hydroxyacides et leurs derives, applications en nutrition, cosmetique et pharmacie
US9370187B2 (en) 2005-05-24 2016-06-21 Selenium, Ltd. Selenium-based biocidal formulations and methods of use thereof
ES2684090T3 (es) * 2005-05-24 2018-10-01 Selenium, Ltd. Formulaciones biocidas basadas en selenio y métodos de uso de las mismas
WO2010080086A1 (en) 2009-01-12 2010-07-15 Selenium, Ltd. Anti-microbial orthodontic compositions and appliances and methods of production and use thereof
WO2014003950A2 (en) * 2012-06-29 2014-01-03 Sena Research, Inc. Selenium containing nucleosides as nutritional supplements
US9987241B2 (en) 2014-09-25 2018-06-05 The Board Of Regents Of The University Of Oklahoma Enzyme conjugate and prodrug cancer therapy
WO2020032951A1 (en) 2018-08-09 2020-02-13 The Board Of Regents Of The University Of Oklahoma Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4512977A (en) 1979-10-18 1985-04-23 Lundy Research Laboratories, Inc. Therapeutic selenium compositions and the use thereof
US5104852A (en) 1989-02-27 1992-04-14 The Ohio State University Method for the inhibition of the proliferation of cancer cells in a tumor sensitive to treatment with a selenodithiol by the injection into the tumor of a selenodithiol such as selenodiglutathione
ES2184756T3 (es) 1992-11-19 2003-04-16 Anticancer Inc Uso de metioninasa como agente antitumoral en quimioterapia antimetionina.
US5597829A (en) * 1994-05-09 1997-01-28 Bionumerik Pharmaceuticals, Inc. Lactone stable formulation of camptothecin and methods for uses thereof
US5783454A (en) * 1994-05-17 1998-07-21 Spallholz; Julian E. Method for the preparation of free radical pharmaceuticals using selenium conjugates

Also Published As

Publication number Publication date
US6916793B2 (en) 2005-07-12
DE60015957T2 (de) 2005-11-03
US6653278B1 (en) 2003-11-25
CA2372992C (en) 2008-09-23
CA2372992A1 (en) 2000-11-16
JP5072142B2 (ja) 2012-11-14
WO2000067762A2 (en) 2000-11-16
AU4711100A (en) 2000-11-21
US20030045496A1 (en) 2003-03-06
EP1176968B1 (de) 2004-11-17
AU784612B2 (en) 2006-05-11
JP2002544166A (ja) 2002-12-24
EP1176968A2 (de) 2002-02-06
WO2000067762A3 (en) 2001-04-19

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Legal Events

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