DE60005359D1 - METHOD FOR QUANTITATIVE DETERMINATION OF ALKALOIDS LIKE KOKAIN IN A SOLID SAMPLE AND REAGENT FOR USE IN THIS METHOD - Google Patents

METHOD FOR QUANTITATIVE DETERMINATION OF ALKALOIDS LIKE KOKAIN IN A SOLID SAMPLE AND REAGENT FOR USE IN THIS METHOD

Info

Publication number
DE60005359D1
DE60005359D1 DE60005359T DE60005359T DE60005359D1 DE 60005359 D1 DE60005359 D1 DE 60005359D1 DE 60005359 T DE60005359 T DE 60005359T DE 60005359 T DE60005359 T DE 60005359T DE 60005359 D1 DE60005359 D1 DE 60005359D1
Authority
DE
Germany
Prior art keywords
reagent
liquid
sample
alkaloids
solid sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60005359T
Other languages
German (de)
Other versions
DE60005359T2 (en
Inventor
Vincenzo Vitalone
Andrea Lotti
Massimo Gottardi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AZIENDA PROVINCIALE PER I SERV
Original Assignee
AZIENDA PROVINCIALE PER I SERV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AZIENDA PROVINCIALE PER I SERV filed Critical AZIENDA PROVINCIALE PER I SERV
Publication of DE60005359D1 publication Critical patent/DE60005359D1/en
Application granted granted Critical
Publication of DE60005359T2 publication Critical patent/DE60005359T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

A screening-type process for the quantitative determination of cocaine and other alkaloids which are present in a solid sample and a reagent for use in the process. The process includes the steps of providing a solid sample in a finely divided or powdered form; completely immersing the sample into a liquid reagent providing a constant concentration of hydroxyl groups; maintaining the sample immersed in the liquid at a temperature in a range from 10 to 250 DEG C for a period of time in a range from a few seconds to 48 hours; and analyzing the liquid separated from the solid with a conventional kit for the determination of the said substances in urine. The reagent is a liquid that provides a constant concentration of hydroxyl groups in the range of from 0.04 to 0.33 M and comprises 0.2 M (NH4)2HPO4 with the addition of 5 ml of 25 % NH4OH for each liter thereof.
DE60005359T 1999-07-20 2000-07-14 METHOD FOR QUANTITATIVELY DETERMINING ALKALOIDS LIKE KOKAIN IN A SOLID SAMPLE AND REAGENT FOR USE IN THIS METHOD Expired - Lifetime DE60005359T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITVR990059 1999-07-20
IT1999VR000059A IT1309450B1 (en) 1999-07-20 1999-07-20 PROCEDURE FOR THE QUANTITATIVE DETERMINATION OF COCAINE AND OTHER SIMILAR SUBSTANCES PRESENT IN A SAMPLE OBTAINED FROM A
PCT/IB2000/000966 WO2001006251A2 (en) 1999-07-20 2000-07-14 Process for the quantitative determination of alkaloids such as cocaine in a solid sample and reagent for use in such process

Publications (2)

Publication Number Publication Date
DE60005359D1 true DE60005359D1 (en) 2003-10-23
DE60005359T2 DE60005359T2 (en) 2004-07-22

Family

ID=11428747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60005359T Expired - Lifetime DE60005359T2 (en) 1999-07-20 2000-07-14 METHOD FOR QUANTITATIVELY DETERMINING ALKALOIDS LIKE KOKAIN IN A SOLID SAMPLE AND REAGENT FOR USE IN THIS METHOD

Country Status (7)

Country Link
EP (1) EP1196784B1 (en)
AT (1) ATE250230T1 (en)
AU (1) AU5701000A (en)
DE (1) DE60005359T2 (en)
ES (1) ES2206262T3 (en)
IT (1) IT1309450B1 (en)
WO (1) WO2001006251A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102967523B (en) * 2012-11-18 2014-09-03 中国科学院苏州纳米技术与纳米仿生研究所 Method for detecting cocaine by using quartz crystal microbalance
ITPI20130026A1 (en) * 2013-04-06 2014-10-07 Univ Pisa METHOD AND DEVICE FOR ANALYSIS OF ABUSE DRUGS ON KERATIN MATERIAL
CN104297401B (en) * 2014-07-22 2016-06-08 吉林大学 The HPLC-ELSD content assaying method of songorine in Radix Aconiti Kusnezoffii

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6949344B1 (en) * 1987-12-28 2005-09-27 Psychemical Corporation Hair analysis method
US5910419A (en) * 1997-05-06 1999-06-08 Johnson; Ted Donald Method for forensically screening hair samples for the presence of cannabinoids

Also Published As

Publication number Publication date
EP1196784A2 (en) 2002-04-17
WO2001006251A3 (en) 2001-08-09
ES2206262T3 (en) 2004-05-16
EP1196784B1 (en) 2003-09-17
AU5701000A (en) 2001-02-05
ITVR990059A1 (en) 2001-01-20
ATE250230T1 (en) 2003-10-15
IT1309450B1 (en) 2002-01-23
WO2001006251A2 (en) 2001-01-25
DE60005359T2 (en) 2004-07-22

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