DE59801243D1 - Improved process for the preparation of 2-acetylcarboxylic acid esters - Google Patents

Improved process for the preparation of 2-acetylcarboxylic acid esters

Info

Publication number
DE59801243D1
DE59801243D1 DE59801243T DE59801243T DE59801243D1 DE 59801243 D1 DE59801243 D1 DE 59801243D1 DE 59801243 T DE59801243 T DE 59801243T DE 59801243 T DE59801243 T DE 59801243T DE 59801243 D1 DE59801243 D1 DE 59801243D1
Authority
DE
Germany
Prior art keywords
preparation
hydrogenation
condensation
acid esters
degrees
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59801243T
Other languages
German (de)
Inventor
Dr Huber
Dr Eichberger
Harald Poeschko
Gerhard Burschik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
DSM Fine Chemicals Austria Nfg GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM Fine Chemicals Austria Nfg GmbH and Co KG filed Critical DSM Fine Chemicals Austria Nfg GmbH and Co KG
Application granted granted Critical
Publication of DE59801243D1 publication Critical patent/DE59801243D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Preparation of 2-acetylcarboxylic acid esters (I) comprises condensation of an acetic acid ester with an aldehyde, followed by removal of any unreacted educts and water formed during condensation and hydrogenation of the resulting intermediate. Preparation of 2-acetylcarboxylic acid esters (I) comprises reacting an acetic acid ester with an aldehyde, followed by hydrogenation. The novelty comprises four factors: (1) During the first stage, the use of acetic acid 1-6C alkyl esters and 1-12C aldehydes, in the presence of a condensation catalyst at 0-40 degrees C; (2) Removal of any unreacted educt and any water produced after the condensation has taken place; (3) Hydrogenation of the residue in the presence of a catalyst at 20-160 degrees C and 1-100 bar, where the hydrogenation is divided into two stages, with the first stage taking place at 20-90 degrees C and the second at 50-160 C; and (4) Isolation of (I) by distillation.
DE59801243T 1997-12-29 1998-12-22 Improved process for the preparation of 2-acetylcarboxylic acid esters Expired - Lifetime DE59801243D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0219397A AT407249B (en) 1997-12-29 1997-12-29 IMPROVED METHOD FOR PRODUCING 2-ACETYL CARBONIC ACID ESTERS

Publications (1)

Publication Number Publication Date
DE59801243D1 true DE59801243D1 (en) 2001-09-27

Family

ID=3529713

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59801243T Expired - Lifetime DE59801243D1 (en) 1997-12-29 1998-12-22 Improved process for the preparation of 2-acetylcarboxylic acid esters

Country Status (9)

Country Link
US (1) US6090975A (en)
EP (1) EP0927713B1 (en)
JP (1) JPH11263753A (en)
AT (2) AT407249B (en)
CZ (1) CZ293178B6 (en)
DE (1) DE59801243D1 (en)
DK (1) DK0927713T3 (en)
ES (1) ES2162386T3 (en)
HU (1) HU225622B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19956410A1 (en) * 1999-11-24 2001-05-31 Oxeno Olefinchemie Gmbh Process for performing aldol condensations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE760034A (en) * 1969-12-08 1971-06-08 Ici Ltd PRODUCTION OF ESTERS
DE2654850C2 (en) * 1976-12-03 1984-04-12 Hoechst Ag, 6230 Frankfurt Process for the preparation of condensation products from lower alkanoyl acetic acid alkyl esters and aliphatic or benzaldehydes in the presence of lower trialkylamines
DE3227388A1 (en) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING (ALPHA) SUBSTITUTED SS-DICARBONYL, SS-CYANCARBONYL AND SS-DICYAN COMPOUNDS
US5731453A (en) * 1996-03-12 1998-03-24 Ube Industries, Ltd. Process for producing a diaryl carbonate
US5786501A (en) * 1996-03-13 1998-07-28 Lonza Ag Process for the preparation of pure alkyl alkylacetoacetates

Also Published As

Publication number Publication date
ATE204562T1 (en) 2001-09-15
HUP9803025A1 (en) 1999-12-28
CZ293178B6 (en) 2004-02-18
DK0927713T3 (en) 2001-10-08
EP0927713A1 (en) 1999-07-07
CZ414798A3 (en) 1999-07-14
HU9803025D0 (en) 1999-02-01
ES2162386T3 (en) 2001-12-16
US6090975A (en) 2000-07-18
ATA219397A (en) 2000-06-15
HU225622B1 (en) 2007-05-02
EP0927713B1 (en) 2001-08-22
JPH11263753A (en) 1999-09-28
AT407249B (en) 2001-01-25

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Legal Events

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8364 No opposition during term of opposition