DE59801243D1 - Improved process for the preparation of 2-acetylcarboxylic acid esters - Google Patents

Improved process for the preparation of 2-acetylcarboxylic acid esters

Info

Publication number
DE59801243D1
DE59801243D1 DE59801243T DE59801243T DE59801243D1 DE 59801243 D1 DE59801243 D1 DE 59801243D1 DE 59801243 T DE59801243 T DE 59801243T DE 59801243 T DE59801243 T DE 59801243T DE 59801243 D1 DE59801243 D1 DE 59801243D1
Authority
DE
Germany
Prior art keywords
preparation
hydrogenation
condensation
acid esters
degrees
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59801243T
Other languages
German (de)
Inventor
Dr Huber
Dr Eichberger
Harald Poeschko
Gerhard Burschik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
DSM Fine Chemicals Austria Nfg GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM Fine Chemicals Austria Nfg GmbH and Co KG filed Critical DSM Fine Chemicals Austria Nfg GmbH and Co KG
Application granted granted Critical
Publication of DE59801243D1 publication Critical patent/DE59801243D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Abstract

Preparation of 2-acetylcarboxylic acid esters (I) comprises condensation of an acetic acid ester with an aldehyde, followed by removal of any unreacted educts and water formed during condensation and hydrogenation of the resulting intermediate. Preparation of 2-acetylcarboxylic acid esters (I) comprises reacting an acetic acid ester with an aldehyde, followed by hydrogenation. The novelty comprises four factors: (1) During the first stage, the use of acetic acid 1-6C alkyl esters and 1-12C aldehydes, in the presence of a condensation catalyst at 0-40 degrees C; (2) Removal of any unreacted educt and any water produced after the condensation has taken place; (3) Hydrogenation of the residue in the presence of a catalyst at 20-160 degrees C and 1-100 bar, where the hydrogenation is divided into two stages, with the first stage taking place at 20-90 degrees C and the second at 50-160 C; and (4) Isolation of (I) by distillation.
DE59801243T 1997-12-29 1998-12-22 Improved process for the preparation of 2-acetylcarboxylic acid esters Expired - Lifetime DE59801243D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0219397A AT407249B (en) 1997-12-29 1997-12-29 IMPROVED METHOD FOR PRODUCING 2-ACETYL CARBONIC ACID ESTERS

Publications (1)

Publication Number Publication Date
DE59801243D1 true DE59801243D1 (en) 2001-09-27

Family

ID=3529713

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59801243T Expired - Lifetime DE59801243D1 (en) 1997-12-29 1998-12-22 Improved process for the preparation of 2-acetylcarboxylic acid esters

Country Status (9)

Country Link
US (1) US6090975A (en)
EP (1) EP0927713B1 (en)
JP (1) JPH11263753A (en)
AT (2) AT407249B (en)
CZ (1) CZ293178B6 (en)
DE (1) DE59801243D1 (en)
DK (1) DK0927713T3 (en)
ES (1) ES2162386T3 (en)
HU (1) HU225622B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19956410A1 (en) * 1999-11-24 2001-05-31 Oxeno Olefinchemie Gmbh Process for performing aldol condensations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE760034A (en) * 1969-12-08 1971-06-08 Ici Ltd PRODUCTION OF ESTERS
DE2654850C2 (en) * 1976-12-03 1984-04-12 Hoechst Ag, 6230 Frankfurt Process for the preparation of condensation products from lower alkanoyl acetic acid alkyl esters and aliphatic or benzaldehydes in the presence of lower trialkylamines
DE3227388A1 (en) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING (ALPHA) SUBSTITUTED SS-DICARBONYL, SS-CYANCARBONYL AND SS-DICYAN COMPOUNDS
US5731453A (en) * 1996-03-12 1998-03-24 Ube Industries, Ltd. Process for producing a diaryl carbonate
US5786501A (en) * 1996-03-13 1998-07-28 Lonza Ag Process for the preparation of pure alkyl alkylacetoacetates

Also Published As

Publication number Publication date
ATE204562T1 (en) 2001-09-15
EP0927713B1 (en) 2001-08-22
JPH11263753A (en) 1999-09-28
CZ293178B6 (en) 2004-02-18
ES2162386T3 (en) 2001-12-16
DK0927713T3 (en) 2001-10-08
US6090975A (en) 2000-07-18
HU225622B1 (en) 2007-05-02
EP0927713A1 (en) 1999-07-07
HUP9803025A1 (en) 1999-12-28
ATA219397A (en) 2000-06-15
CZ414798A3 (en) 1999-07-14
AT407249B (en) 2001-01-25
HU9803025D0 (en) 1999-02-01

Similar Documents

Publication Publication Date Title
DE69517832D1 (en) A process for the preparation of tetrazolyl compounds
DE69608635T2 (en) Process for the production of acetic acid by carbonylation of dimethyl ether
DE50005769D1 (en) Process for the preparation of di (meth) acrylic esters
DE59801243D1 (en) Improved process for the preparation of 2-acetylcarboxylic acid esters
EP0812309A4 (en) Process for preparation of cinnamate sunscreen agents
DE69028833T2 (en) METHOD FOR PRODUCING UNSATURATED KETONES
DE50004236D1 (en) Process for the preparation of 1,1,4,4-tetramethoxybutene-2
FI922170A (en) CHEMICAL PROCESS
ES2183469T3 (en) PROCEDURE FOR OBTAINING HIGHER INSATURED KETONES.
ATE105545T1 (en) PROCESS FOR THE PREPARATION OF ALKOXYALKYLIDEMALONONIC ACID ESTERS.
DE59201724D1 (en) Process for the preparation of higher alcohols by catalytic hydrogenation of carboxylic acid alkyl esters.
ATE13674T1 (en) PROCESS FOR PREPARING ALPHA-DICYANOTRIMETHYL-SILYLOXY COMPOUNDS (I).
ATE68780T1 (en) PROCESS FOR PRODUCTION OF GLYOXYLIC ACID.
DE3878006D1 (en) METHOD FOR PRODUCING CARBONIC ACID METHYL ESTERS.
ATE207908T1 (en) METHOD FOR PRODUCING 2-ALKOXY-6-(TRIFLUORMETHYL)-PYRIMIDINE-4-OL
NO974340L (en) Process for the preparation of 3-pentenoic acid esters by carbonylation of alkoxybutenes
ATE13289T1 (en) PROCESS FOR THE PREPARATION OF 4ALKOXYACETESSE ESTERS.
ATE33821T1 (en) PROCESS FOR THE PREPARATION OF HALOGENATED 3,3-DIMETHYL-5-HEXEN-2-ONES.
EP0350686A3 (en) Process for the preparation of 6-hydroxycapronic-acid esters
DE60100185T2 (en) Production of carboxylic acid ester catalyzed by a sulfonic acid
TW430655B (en) Process for the preparation of acid chloride compounds
ATE231125T1 (en) SIMPLE PROCESS FOR PRODUCING HIGH QUALITY CAPTROPRIL
ATE8245T1 (en) PROCESS FOR THE RECYCLING OF BY-PRODUCTS IN THE MANUFACTURE OF LOWER GALCYLESTERS OF 3,3-DIMETHYL-4-PENTENE ACID.
ES8705880A1 (en) Symmetrical benzofuryl di:methyl di:hydro-pyridine di:ester prepn.
DE59108052D1 (en) Process for the production of procaine

Legal Events

Date Code Title Description
8364 No opposition during term of opposition