DE504499C - Process for the representation of liquid bodies in a highly enriched solid form - Google Patents

Process for the representation of liquid bodies in a highly enriched solid form

Info

Publication number
DE504499C
DE504499C DED51489D DED0051489D DE504499C DE 504499 C DE504499 C DE 504499C DE D51489 D DED51489 D DE D51489D DE D0051489 D DED0051489 D DE D0051489D DE 504499 C DE504499 C DE 504499C
Authority
DE
Germany
Prior art keywords
liquid
representation
solid form
highly enriched
enriched solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DED51489D
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German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CURT VON DUHN
Original Assignee
CURT VON DUHN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CURT VON DUHN filed Critical CURT VON DUHN
Priority to DED51489D priority Critical patent/DE504499C/en
Application granted granted Critical
Publication of DE504499C publication Critical patent/DE504499C/en
Expired legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Colloid Chemistry (AREA)

Description

Verfahren zur Darstellung von flüssigen Körpern in hoch angereicherter fester Gebrauchsform Manche Gegenstände des täglichen Gebrauchs, die unter gewöhnlichen Bedingungen flüssig sind, besitzen in dieser flüssigen Form Eigenschaften; die die Anwendung unangenehm machen, oder die für den Gebrauch unzweckmäßig sind. Um solche Übelstände auszuschalten, griff man zu verschiedenen Hilfsmitteln. Z. B. schloß man die Flüssigkeiten in Kapseln ein, oder man nahm eine chemische Veränderung mit ihnen vor durch Verseifung oder sonstige Bindung. Die Kapseln sind verhältnismäßig teuer, oft unbequem, die chemische Bindung konnte die Körper so verändern, daß die erwünschten Eigenschaften gemindert, unerwünschte herbeigeführt wurden.Process for the representation of liquid bodies in highly enriched fixed form of use Some objects of daily use that fall under ordinary Conditions that are liquid have properties in this liquid form; the the Make application uncomfortable or which are inconvenient for use. To such To eliminate ills, one resorted to various aids. E.g. closed you put the liquids in capsules, or you took a chemical change with you before them by saponification or other binding. The capsules are proportionate expensive, often inconvenient, the chemical bond could change the body in such a way that the desired properties were reduced, undesirable effects were brought about.

Das vorliegende Verfahren will die Flüssigkeiten in eine fest erscheinende Form bringen, ohne sie in Kapseln zu füllen oder sie chemisch zu verändern.The present method aims to transform the liquids into a solid-appearing one Bring shape without filling into capsules or chemically altering them.

Es geht von zwei Tatsachen aus, die an sich bisher schon bekannt waren: erstens, daß in einem dispersen System, dem ein Schutzkolloid zugesetzt wird, z. B. der Emulsion einer Flüssigkeit in einer anderen, die einzelnen Teile der dispersen Phase hüllenartig von dem Schutzkolloid umgeben werden; zweitens, daß man viele als Schutzkolloid verwendbare Körper organischen Ursprungs durch Gerbstoffe härten kann.It is based on two facts that were already known per se: first, that in a disperse system to which a protective colloid is added, e.g. B. the emulsion of one liquid in another, the individual parts of the disperse Phase are surrounded by the protective colloid like a shell; second, that there are many Hardening bodies of organic origin that can be used as protective colloids by means of tannins can.

Bei der Anwendung des Verfahrens emulgiert man die betreffende Flüssigkeit in einem geeigneten Dispersionsmittel, dem ein härtbares Schutzkolloid zuzufügen ist. Durch Zusatz eines gerbenden Mittels zu der Emulsion werden alsdann die Schutzhüllen, in denen die Teile der dispersen Phase eingeschlossen sind, gehärtet. Die Emulsion erstarrt dadurch zunächst zu einem Gel, aus dem sich nach Entfernung des Dispersionsmittels ein glasharter Körper abscheidet. Die spröde Masse dieses Körpers wird von dem gehärteten Schutzkolloid gebildet, in dem die emulgiert gewesene Flüssigkeit in mikroskopisch kleinen Tropfen eingeschlossen ist. Durch Zerkleinern läßt sich die Masse in die Form eines Pulvers bringen, dessen Korngröße nicht kleiner sein darf als ein einzelnes eingeschlossenes Teilchen der Flüssigkeit mit seiner Hülle, weil sonst die Flüssigkeit austreten würde. Wird bei der Zerkleinerung ein Teil der gehärteten Schutzhüllen zertrümmert, so muß der Anteil ausgetretener Flüssigkeit durch Waschen mit einem Lösungsmittel entfernt werden.When the process is used, the liquid in question is emulsified in a suitable dispersant to which a hardenable protective colloid is added is. By adding a tanning agent to the emulsion, the protective covers, in which the parts of the disperse phase are included, hardened. The emulsion thereby initially solidifies to a gel, from which after removal of the dispersant a glass-hard body is deposited. The brittle mass of this body is hardened by the one Protective colloid formed in which the liquid was emulsified in microscopic small drop is included. The mass can be broken up into the Bring the form of a powder, the grain size of which must not be smaller than a single one trapped particle of the liquid with its shell, otherwise the liquid would emerge. Becomes a part of the hardened protective cover during the shredding smashed, so the portion of leaked liquid must by washing with a Solvents are removed.

Beispiel i 3 g Gelatine werden in 379 Wasser bei gelinder Wärme gelöst, die Lösung wird mit 2o g Ricinusöl zu einer Emulsion verschüttelt. Nach Zusatz von i g Tannin D. A. B. 6 erstarrt die Emulsion zu einem Gel, das getrocknet einen glasigen, spröden Rückstand läßt, der -- notfalls mit nachfolgender kurzer Waschung - durch Mahlung oder auf andere Weise zerkleinert werden kann. Die Endmasse, ein weißes Pulver; ist bei einem Gehalt von 8o bis 85 Hundertteilen Ricinusöl völlig geschmacklos.Example i 3 g of gelatin are dissolved in 379 g of water under gentle heat, the solution is shaken with 20 g of castor oil to form an emulsion. After adding ig Tannin DAB 6, the emulsion solidifies to a gel which, when dry, leaves a glassy, brittle residue which - if necessary with a subsequent brief washing - can be comminuted by grinding or in some other way. The final mass, a white powder; is completely tasteless at a content of 80 to 85 percent castor oil.

Beispiele 39 getrocknetes Hühnereiweiß werden in 37 g Wasser gelöst und die Lösung mit 2o g Lebertran emulgiert. Durch Formaldehydzusatz (3 ccm Formaldehydlösung D. A. B. 6) wird das Eiweiß gehärtet. Man verfährt weiter wie in Beispiel i und erhält ein gelbes, geschmackloses Pulver mit 8o bis 85 Hundertteilen Gehalt an Lebertran.EXAMPLES 39 Dried chicken egg whites are dissolved in 37 g of water and the solution is emulsified with 20 g of cod liver oil. The protein is hardened by adding formaldehyde (3 ccm formaldehyde solution DAB 6). Proceed as in Example i and a yellow, tasteless powder with 80 to 85 percent content of cod liver oil is obtained.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung von flüssigen Körpern in hoch angereicherter fester Gebrauchsform, dadurch gekennzeichnet, daß die Gebrauchsflüssigkeit mit einem Dispersionsmittel unter Zusatz eines härtbaren Schutzkolloids emulgiert und aus der Emulsion nach Zusatz eines gerbenden Mittels in Form eines Gels ausgefällt wird, 'das nach Entfernung des Dispersionsrnittels zu einer mahlbaren Masse erhärtet, in der die Flüssigkeit in mikroskopisch kleinen Umhüllungen enthalten ist. Claim: method for the representation of liquid bodies in highly enriched solid form, characterized in that the liquid is emulsified with a dispersant with the addition of a hardenable protective colloid and precipitated from the emulsion after the addition of a tanning agent in the form of a gel, 'which after removal of the Dispersion agent hardens to a grindable mass in which the liquid is contained in microscopic envelopes.
DED51489D 1926-10-21 1926-10-21 Process for the representation of liquid bodies in a highly enriched solid form Expired DE504499C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DED51489D DE504499C (en) 1926-10-21 1926-10-21 Process for the representation of liquid bodies in a highly enriched solid form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DED51489D DE504499C (en) 1926-10-21 1926-10-21 Process for the representation of liquid bodies in a highly enriched solid form

Publications (1)

Publication Number Publication Date
DE504499C true DE504499C (en) 1930-08-04

Family

ID=7053415

Family Applications (1)

Application Number Title Priority Date Filing Date
DED51489D Expired DE504499C (en) 1926-10-21 1926-10-21 Process for the representation of liquid bodies in a highly enriched solid form

Country Status (1)

Country Link
DE (1) DE504499C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570604A1 (en) * 1984-09-25 1986-03-28 Pharmedis Sa New method of encapsulation of volatile substances and phyto-aromatic compositions thereby obtained

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570604A1 (en) * 1984-09-25 1986-03-28 Pharmedis Sa New method of encapsulation of volatile substances and phyto-aromatic compositions thereby obtained

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