DE50108086D1 - METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATION - Google Patents
METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATIONInfo
- Publication number
- DE50108086D1 DE50108086D1 DE50108086T DE50108086T DE50108086D1 DE 50108086 D1 DE50108086 D1 DE 50108086D1 DE 50108086 T DE50108086 T DE 50108086T DE 50108086 T DE50108086 T DE 50108086T DE 50108086 D1 DE50108086 D1 DE 50108086D1
- Authority
- DE
- Germany
- Prior art keywords
- receptors
- cell activation
- exogenous
- endogenous cell
- exogenerous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/50—Lipopolysaccharides; LPS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Analyzing exogenous and endogenous cell activation comprises measuring the assembly of receptors into a CD14-containing receptor cluster (RC), is new. Independent claims are also included for the following: (1) diagnosing: (i) systemic inflammation: or (ii) arteriosclerosis or inflammatory disease of coronary/cerebral arteries, or their precursors, by using the new method to determine energy transfer in monocytes; and (2) treatment of the specified conditions with compounds (I) that neutralize exogenous or endogenous proinflammatory molecules, phospholipids, complement-regulating proteins, Fc psi or scavenger receptors, integrin-associated proteins, lipopolysaccharide (LPS)-associated receptors and/or G-protein receptors.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE50108086T DE50108086D1 (en) | 2000-06-05 | 2001-03-05 | METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATION |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10027308A DE10027308A1 (en) | 2000-06-05 | 2000-06-05 | Analyzing endogenous or exogenous cell activation for the diagnosis of e.g systemic inflammation comprises measuring assembly of CD14-containing receptor cluster |
PCT/DE2001/000817 WO2001065257A2 (en) | 2000-03-03 | 2001-03-05 | Method for the analysis of exogenic and endogenic cell activation |
DE50108086T DE50108086D1 (en) | 2000-06-05 | 2001-03-05 | METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATION |
Publications (1)
Publication Number | Publication Date |
---|---|
DE50108086D1 true DE50108086D1 (en) | 2005-12-22 |
Family
ID=7644423
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10027308A Ceased DE10027308A1 (en) | 2000-03-03 | 2000-06-05 | Analyzing endogenous or exogenous cell activation for the diagnosis of e.g systemic inflammation comprises measuring assembly of CD14-containing receptor cluster |
DE50108086T Expired - Fee Related DE50108086D1 (en) | 2000-06-05 | 2001-03-05 | METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATION |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10027308A Ceased DE10027308A1 (en) | 2000-03-03 | 2000-06-05 | Analyzing endogenous or exogenous cell activation for the diagnosis of e.g systemic inflammation comprises measuring assembly of CD14-containing receptor cluster |
Country Status (2)
Country | Link |
---|---|
AT (1) | ATE310246T1 (en) |
DE (2) | DE10027308A1 (en) |
-
2000
- 2000-06-05 DE DE10027308A patent/DE10027308A1/en not_active Ceased
-
2001
- 2001-03-05 AT AT01929228T patent/ATE310246T1/en not_active IP Right Cessation
- 2001-03-05 DE DE50108086T patent/DE50108086D1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE310246T1 (en) | 2005-12-15 |
DE10027308A1 (en) | 2001-12-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2160714T3 (en) | ANALYSIS AND DEVICES FOR THE DETECTION OF EXTRAHEPATIC BILIAR ATRESIA. | |
BRPI0415092A (en) | diagnostic test device and method of use | |
DK0429612T3 (en) | Optical analysis method | |
ATE347594T1 (en) | MONOCYTE PROTEIN RECEPTORS FROM MAMMALS, WITH CHEMOATTRACTION TRIGGERING EFFECT | |
DE69837087D1 (en) | ANALYSIS DEVICE WITH REMOVABLE ELEMENT | |
SE8404895D0 (en) | MEANS AND SET FOR A SENSITIVITY TEST | |
DK0516746T3 (en) | Oral collection for immunoassay | |
BG104275A (en) | Method and device for express analysis of tested parameters in biological samples | |
ES532954A0 (en) | A TEST DEVICE TO DETERMINE THE PRESENCE OF A SUBSTANCE IN A SAMPLE TO BE TESTED | |
EP1505364A3 (en) | Apparatus and method for parallel interferometric measurement using an expanded local oscillator signal | |
EA199800493A1 (en) | ANALYSIS OF BLOOD AT THE RATIO OF ACTIVITY OF FACTOR V FOR EVALUATING THE PROBABILITY OF DISEASE BY THROMBOEMBOLIA | |
IT1206532B (en) | MUCOSAL ALLERGY-DIAGNOSTIC METHOD AND ITS DEVICE FOR IN VIVO SURVEYING OF SPECIFIC AND TOTAL IGE | |
ATE258310T1 (en) | TEST METHODS FOR COLLAGEN PEPTIDE | |
DK1285301T3 (en) | Device for sequential observation of samples as well as methods to which it is used | |
DE50108086D1 (en) | METHOD FOR THE ANALYSIS OF EXOGENEROUS AND ENDOGENOUS CELL ACTIVATION | |
BR0211350A (en) | Homogeneous biopolymer binding assay by multiple measurements under varying conditions | |
RU2004109985A (en) | METHOD AND KIT FOR DETERMINATION OF ALLERGEN-INDUCED BASOPHILES ACTIVATION FOR DETERMINING HYPERSENSITIVITY TO SOME SUBSTANCES | |
ATE223055T1 (en) | METHOD FOR DIAGNOSING CHLAMYDIA IN A BIOLOGICAL EXTRACELLULAR FLUID | |
BR0206233A (en) | Test device | |
AR009406A1 (en) | METHOD AND DEVICE TO MEASURE THE CONCENTRATION OF AIRPORTED FIBERS | |
ES2173146T3 (en) | IMMUNOLOGICAL TEST FOR THE QUANTIFICATION OF THE HUMAN ESTIMULATION FACTOR OF HUMAN GRANULOCIT COLONIES MODIFIED BY PEG. | |
Vogt Jr | Use of laboratory tests for immune biomarkers in environmental health studies concerned with exposure to indoor air pollutants. | |
ATE421093T1 (en) | RAPID DETERMINATION OF DIFFERENT FORMS OF HGF (HEPTOCYTE GROWTH FACTOR) IN THE BODY FLUID | |
BR9608331A (en) | Method for spectroscopic analysis of inhomogeneous sample | |
DE50113202D1 (en) | METHOD FOR THE ANALYSIS OF CHAIR SAMPLES FOR DIAGNOSTIC PURPOSES |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |