DE50015133D1 - NUCLEIC ACID SEQUENCES OF HYPERPLASIEN AND TARGETS OF THE THYROID - Google Patents

NUCLEIC ACID SEQUENCES OF HYPERPLASIEN AND TARGETS OF THE THYROID

Info

Publication number
DE50015133D1
DE50015133D1 DE50015133T DE50015133T DE50015133D1 DE 50015133 D1 DE50015133 D1 DE 50015133D1 DE 50015133 T DE50015133 T DE 50015133T DE 50015133 T DE50015133 T DE 50015133T DE 50015133 D1 DE50015133 D1 DE 50015133D1
Authority
DE
Germany
Prior art keywords
nucleic acid
hyperplasien
thyroid
targets
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50015133T
Other languages
German (de)
Inventor
Joern Bullerdiek
Volkhard Rippe
Maren Meiboom
Gazanfer Belge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Bremen
Original Assignee
Universitaet Bremen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Bremen filed Critical Universitaet Bremen
Application granted granted Critical
Publication of DE50015133D1 publication Critical patent/DE50015133D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

The invention relates to a nucleic acid which codes for a polypeptide. Said polypeptide comprises a KRAB domain and/or at least one zinc finger motif, whereby the KRAB domain contains the amino acid sequence of SEQ ID NO: 1 and the zinc finger motif is of the type contained in the zinc finger domain with the amino acid sequence of SEQ ID NO: 2.
DE50015133T 1999-10-12 2000-10-11 NUCLEIC ACID SEQUENCES OF HYPERPLASIEN AND TARGETS OF THE THYROID Expired - Lifetime DE50015133D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19949179A DE19949179A1 (en) 1999-10-12 1999-10-12 Nucleic acid sequences from hyperplasias and thyroid tumors
PCT/DE2000/003600 WO2001027265A1 (en) 1999-10-12 2000-10-11 Nucleic acid sequences of hyperplasia and tumours of the thyroid

Publications (1)

Publication Number Publication Date
DE50015133D1 true DE50015133D1 (en) 2008-06-05

Family

ID=7925380

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19949179A Ceased DE19949179A1 (en) 1999-10-12 1999-10-12 Nucleic acid sequences from hyperplasias and thyroid tumors
DE50015133T Expired - Lifetime DE50015133D1 (en) 1999-10-12 2000-10-11 NUCLEIC ACID SEQUENCES OF HYPERPLASIEN AND TARGETS OF THE THYROID

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19949179A Ceased DE19949179A1 (en) 1999-10-12 1999-10-12 Nucleic acid sequences from hyperplasias and thyroid tumors

Country Status (7)

Country Link
US (1) US20070020275A1 (en)
EP (1) EP1220921B1 (en)
JP (1) JP2003511069A (en)
AT (1) ATE393224T1 (en)
AU (1) AU1993201A (en)
DE (2) DE19949179A1 (en)
WO (1) WO2001027265A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1266001A2 (en) * 2000-03-13 2002-12-18 Incyte Genomics, Inc. Human transcription factors
US7906477B2 (en) * 2002-11-18 2011-03-15 Genspera, Inc. Activation of peptide prodrugs by hK2
ATE481936T1 (en) * 2007-06-25 2010-10-15 Terumo Corp MEDICAL DEVICE
AU2008307643B9 (en) 2007-09-28 2014-04-17 Intrexon Corporation Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
EP2473628A1 (en) 2009-08-31 2012-07-11 Alcedo Biotech GmbH Microrna-based methods and compositions for the diagnosis, prognosis and treatment of tumor involving chromosomal rearrangements

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763209A (en) * 1988-09-26 1998-06-09 Arch Development Corporation Methods and materials relating to the functional domains of DNA binding proteins

Also Published As

Publication number Publication date
JP2003511069A (en) 2003-03-25
WO2001027265A1 (en) 2001-04-19
EP1220921A1 (en) 2002-07-10
EP1220921B1 (en) 2008-04-23
DE19949179A1 (en) 2001-05-03
ATE393224T1 (en) 2008-05-15
US20070020275A1 (en) 2007-01-25
AU1993201A (en) 2001-04-23

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Legal Events

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8364 No opposition during term of opposition