DE4412190A1 - Prevention of snoring - Google Patents

Prevention of snoring

Info

Publication number
DE4412190A1
DE4412190A1 DE19944412190 DE4412190A DE4412190A1 DE 4412190 A1 DE4412190 A1 DE 4412190A1 DE 19944412190 DE19944412190 DE 19944412190 DE 4412190 A DE4412190 A DE 4412190A DE 4412190 A1 DE4412190 A1 DE 4412190A1
Authority
DE
Grant status
Application
Patent type
Prior art keywords
substance
biocompatible
snoring
prevention
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19944412190
Other languages
German (de)
Inventor
Hans Dr Dr Schreiber
Original Assignee
Schreiber Hans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Abstract

Prevention of rhenchopathy (snoring) comprises injecting a biocompatible substance, esp. a biological substance, into or around the velum in order to tighten the tissue. The biocompatible substance is pref. a cross-linked collagen or a substance having a similar activity.

Description

Die Rhenchopathie oder in der Umgangssprache das Schnarchen ist eine Form der Belästigung des sozialen Umfeldes, das oft zu familiären Spannungen führt. The Rhenchopathie or in slang snoring is a form of harassment of the social environment, which often leads to family tensions.

Sie oder es tritt überwiegend in Schlafrückenlage auf und ist durch Schwingungen oder Flattern des weichen Gaumensegels, auch Velum genannt, bedingt. She or it occurs predominantly in sleep supine and is called by vibrations or fluttering of the soft palate, and velum caused. Das Zurückfallen der Zunge, die Behinderung der Nasenatmung und andere Faktoren sind zusätzlich zu benennen. Falling back of the tongue, nasal congestion and other factors are to be named in addition. Eine besondere pathologische Form stellt die Rhenchopathie in Kombination mit der sog. Schlafapnoe dar, bei der es zum kurzfristigen Atemstillstand kommt. A special pathological form, the Rhenchopathie is combined with the so-called. Sleep apnea, when it comes to short-term respiratory arrest.

Als Gegenmaßnahmen werden va eine Verhinderung der Rückenlage und in Extremfällen eine straffend Gaumensegelplastik empfohlen. As countermeasures preventing the supine position and, in extreme cases, a firming soft palate plastic are recommended va.

Nun ist seit einigen Jahren in der plastischen Chirurgie als Alternative zum Skalpell bei Narbenkorrekturen die gezielte Injektion von Rindercollagen bekannt, das allerdings einen hohen Grad an früher Resorption aufweist. Now the targeted injection of bovine collagen for several years in plastic surgery as an alternative to scalpel in scar correction is known which, however, has a high degree of earlier resorption.

Fibrilläres Collagen besteht aus sich wiederholenden Polypeptid-Untereinheiten, genannt Tropocollagen. Fibrillar collagen consists of repetitive polypeptide subunits, called tropocollagen. Diese sind zu parallelen Bündeln angeordnet und weisen eine charakteristische 64-nm lange Querstreifung zumindest bei den meisten Collagenen auf. These are arranged to be parallel bundles and have a characteristic 64-nm long striations at least for the most collagens on.

Es besteht die Möglichkeit, über den Chemismus Collagen mit seinem ungewöhnlich hohen Anteil von Prolin- und Hydroxyprolinresten zusätzlich kovalent quer zu vernetzen. It is possible to crosslink by the chemistry of collagen, with its unusually high proportion of proline and hydroxyproline residues additionally covalently cross.

Im Falle der kosmetischen Applikation ist damit die Möglichkeit geschaffen, das Collagen nicht nur subcutan zu injizieren und die Resorption zu verzögern. In the case of cosmetic application thus creates the possibility to inject the collagen not only subcutaneously and delay absorption.

Aus diesem Grundgedanken heraus entstand der erfinderische Gedanke, quervernetztes Collagen, bevorzugt mit biologischen und/oder bioaktiven Füllstoffen ins Velum zu applizieren, um auf diesem Wege eine angestrebte Velumstraffung ohne phonetische Beeinträchtigungen zu schaffen. For this reason, thought out the inventive concept, cross-linked collagen, preferably to be applied to biological and / or bioactive fillers into the soft palate to create in this way a target Velumstraffung without phonetic impairment arose.

Wirkstoff und Anwendung sind in Verbindung mit der Beschreibung den Ansprüchen zu entnehmen. Drug application and can be found in connection with the description of the claims.

Claims (9)

  1. 1. Verfahren zur Anwendung rhenchodepressiver Substanzen, dadurch gekennzeichnet, daß biokompatibles, besser biologisches Material ins bzw. um das weiche Gaumensegel injiziert wird, um dessen Straffung bei Indikation der Rhenchopathie zu bewirken. 1. A method for application rhenchodepressiver substances, characterized in that biocompatible, better biological material is injected into or around the soft palate to cause its tightening on the indication Rhenchopathie.
  2. 2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Substanz nach Verträglichkeitstestung angewandt wird. 2. The method according to claim 1, characterized in that the substance is applied after compatibility testing.
  3. 3. Verfahren nach mindestens einem der Ansprüche 1, 2, dadurch gekennzeichnet, daß bevorzugt die Substanz sukzessive und beginnend mit kleinen Dosen unter Beachtung der Stimmveränderung injiziert wird. 3. A method according to any one of claims 1, 2, characterized in that preferably, the substance is successively and starting injected with small doses in accordance with the voice change.
  4. 4. Verfahren nach mindestens einem der Ansprüche 1-3, dadurch gekennzeichnet, daß die Substanz nach Grenzresorption nachinjiziert wird. 4. The method according to any one of claims 1-3, characterized in that the substance is re-injected after Grenzresorption.
  5. 5. Verfahren nach mindestens einem der Ansprüche 1-4, dadurch gekennzeichnet, daß bevorzugt mit inerten oder bioaktiven Füllkörpern quervernetztes Collagen seitlich und/oder um die Umgebung des Frenulums injiziert wird. 5. The method according to any one of claims 1-4, characterized in that preferably crosslinked with inert packings or bioactive collagen is injected laterally and / or around the vicinity of the frenulum.
  6. 6. Verfahren nach mindestens einem der Ansprüche 1-5, dadurch gekennzeichnet, daß das Ende der Rhenchopathie das Ende des vorläufigen therapeutischen Vorgehens bedeutet. 6. The method according to any one of claims 1-5, characterized in that the end of Rhenchopathie means the end of the preliminary therapeutic procedure.
  7. 7. Rhenchodepressive Substanz nach Anspruch 1, dadurch gekennzeichnet, daß diese als Grundgerüst ein quervernetztes Collagen oder eine bioverträgliche Substanz gleicher Wirkung aufweist. 7. Rhenchodepressive substance according to claim 1, characterized in that it comprises the same as the basic structure is a crosslinked collagen or a biocompatible substance effect.
  8. 8. Rhenchodepressive Substanz nach Anspruch 1, 7, dadurch gekennzeichnet, daß miniaturisierte, bevorzugt bioaktive Füllkörper in das quervernetzte Collagen passiv und/oder über chemische Bindung aktiv ins Collagen oder die Substanz gleicher Wirkung eingelagert sind. 8. Rhenchodepressive substance according to claim 1, 7, characterized in that miniaturized, preferably bioactive filler in the crosslinked collagen passive and / or are incorporated via chemical binding to the active substance, the collagen, or an equivalent effect.
  9. 9. Rhenchodepressive Substanz nach mindestens einem der Ansprüche 1, 7, 8, dadurch gekennzeichnet, daß diese bei korrekter Anwendung zu einem Straffungseffekt des Velums geführt hat, ohne negative phonetische Auswirkungen bewirkt zu haben. 9. Rhenchodepressive substance according to at least one of claims 1, 7, 8, characterized in that this has resulted in a correct application at a tightening effect of the velum to have no negative effect phonetic effects.
DE19944412190 1994-04-08 1994-04-08 Prevention of snoring Withdrawn DE4412190A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19944412190 DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19944412190 DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Publications (1)

Publication Number Publication Date
DE4412190A1 true true DE4412190A1 (en) 1995-10-12

Family

ID=6514958

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19944412190 Withdrawn DE4412190A1 (en) 1994-04-08 1994-04-08 Prevention of snoring

Country Status (1)

Country Link
DE (1) DE4412190A1 (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6742524B2 (en) 2000-08-10 2004-06-01 Restore Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
JP2004154583A (en) * 1999-09-17 2004-06-03 Restore Medical Inc Medical treatment implant for respirator tract condition
US6848447B2 (en) 1999-09-17 2005-02-01 Restore Medical, Inc. Braided implant for snoring treatment
US7017582B2 (en) 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US7063089B2 (en) 1999-09-17 2006-06-20 Restore Medical Inc. Airway stiffening implant
US7107992B2 (en) 2002-10-04 2006-09-19 Pavad Medical, Inc. System and method for preventing closure of passageways
US7146981B2 (en) 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US7213599B2 (en) 2003-10-31 2007-05-08 Restore Medical, Inc. Airway implant
JP2007512090A (en) * 2003-11-20 2007-05-17 アプネオン,インコーポレイテッド Device for anchoring the tissue in the body region of the pharynx conduit system and method
US7237554B2 (en) 2003-10-31 2007-07-03 Restore Medical, Inc. Airway implant
US7237553B2 (en) 1999-09-17 2007-07-03 Restore Medical, Inc. Needle with pre-loaded implant for snoring treatment
US7322356B2 (en) 2005-02-24 2008-01-29 Restore Medical, Inc. Combination sleep apnea treatment
WO2008097890A2 (en) * 2007-02-02 2008-08-14 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
US7836888B2 (en) 2004-09-21 2010-11-23 Pavad Medical, Incorporated Airway implant and methods of making and using
US7882842B2 (en) 2004-09-21 2011-02-08 Pavad Medical, Inc. Airway implant sensors and methods of making and using the same
US20130087155A1 (en) * 2001-08-31 2013-04-11 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US8578937B2 (en) 2004-09-21 2013-11-12 Medtronic Xomed, Inc. Smart mandibular repositioning system
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US9492592B2 (en) 2007-02-28 2016-11-15 Orthopeutics, L. P. Crosslinker enhanced repair of knee meniscus
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea

Cited By (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7100613B2 (en) 1999-09-17 2006-09-05 Restore Medical Inc. Braided implant for snoring treatment
JP2004154583A (en) * 1999-09-17 2004-06-03 Restore Medical Inc Medical treatment implant for respirator tract condition
US6848447B2 (en) 1999-09-17 2005-02-01 Restore Medical, Inc. Braided implant for snoring treatment
JP4699690B2 (en) * 1999-09-17 2011-06-15 メドトロニック ゾメド, インコーポレイテッドMedtronic Xomed, Inc. Therapeutic implants of the state of the respiratory tract
US7255109B2 (en) 1999-09-17 2007-08-14 Restore Medical, Inc. Polymer palate implant
US7028691B2 (en) 1999-09-17 2006-04-18 Restore Medical Inc. Braided implant for snoring treatment
US7036515B2 (en) 1999-09-17 2006-05-02 Restore Medical Inc. Braided implant for snoring treatment
US7047979B2 (en) 1999-09-17 2006-05-23 Restore Medical Inc. Soft palate implant with fiber construction
US7063089B2 (en) 1999-09-17 2006-06-20 Restore Medical Inc. Airway stiffening implant
US7237553B2 (en) 1999-09-17 2007-07-03 Restore Medical, Inc. Needle with pre-loaded implant for snoring treatment
US7077143B2 (en) 2000-08-10 2006-07-18 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US7077144B2 (en) 2000-08-10 2006-07-18 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US6742524B2 (en) 2000-08-10 2004-06-01 Restore Medical, Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US6971396B2 (en) 2000-08-10 2005-12-06 Restore Medical Inc. Method and apparatus to treat conditions of the naso-pharyngeal area
US7255110B2 (en) 2000-08-10 2007-08-14 Restore Medical, Inc. Injection sleep apnea treatment
US20130087155A1 (en) * 2001-08-31 2013-04-11 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US9192507B2 (en) * 2001-08-31 2015-11-24 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US20160015555A1 (en) * 2001-08-31 2016-01-21 Orthopeutcs. L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US9918870B2 (en) * 2001-08-31 2018-03-20 Orthopeutics, L.P. Tissue crosslinking for treatment of snoring and obstructive sleep apnea
US8037885B2 (en) 2002-02-04 2011-10-18 Restore Medical, Inc. Treatment for sleep apnea or snoring
US7322993B2 (en) 2002-02-04 2008-01-29 Restore Medical Inc. Stiffening pharyngeal wall treatment
US7017582B2 (en) 2002-02-04 2006-03-28 Restore Medical Inc. Stiffening pharyngeal wall treatment
US8864788B2 (en) 2002-02-04 2014-10-21 Medtronic Xomed, Inc. Pharyngeal wall treatment
US8430900B2 (en) 2002-02-04 2013-04-30 Medtronic Xomed, Inc. Pharyngeal wall treatment
US8424531B2 (en) 2002-02-04 2013-04-23 Medtronic Xomed, Inc. Pharyngeal wall treatment
US7669603B2 (en) 2002-02-04 2010-03-02 Medtronic Xomed, Inc. Pharyngeal wall treatment
US7146981B2 (en) 2002-02-04 2006-12-12 Restore Medical, Inc. Pharyngeal wall treatment
US8413662B2 (en) 2002-02-04 2013-04-09 Medtronic Xomed, Inc. Stiffening pharyngeal wall treatment
US7686021B2 (en) 2002-02-04 2010-03-30 Medtronic Xomed, Inc. Pharyngeal tissue stabilization
US7107992B2 (en) 2002-10-04 2006-09-19 Pavad Medical, Inc. System and method for preventing closure of passageways
US7213599B2 (en) 2003-10-31 2007-05-08 Restore Medical, Inc. Airway implant
US7703460B2 (en) 2003-10-31 2010-04-27 Medtronic Xomed, Inc. Tongue implant
US7401611B2 (en) 2003-10-31 2008-07-22 Restore Medical, Inc. Airway implant
US7673635B2 (en) 2003-10-31 2010-03-09 Medtronix Xomed, Inc. Soft palate implant
US7237554B2 (en) 2003-10-31 2007-07-03 Restore Medical, Inc. Airway implant
JP2007512090A (en) * 2003-11-20 2007-05-17 アプネオン,インコーポレイテッド Device for anchoring the tissue in the body region of the pharynx conduit system and method
US7882842B2 (en) 2004-09-21 2011-02-08 Pavad Medical, Inc. Airway implant sensors and methods of making and using the same
US8578937B2 (en) 2004-09-21 2013-11-12 Medtronic Xomed, Inc. Smart mandibular repositioning system
US7836888B2 (en) 2004-09-21 2010-11-23 Pavad Medical, Incorporated Airway implant and methods of making and using
US7322356B2 (en) 2005-02-24 2008-01-29 Restore Medical, Inc. Combination sleep apnea treatment
WO2008097890A3 (en) * 2007-02-02 2009-09-17 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
WO2008097890A2 (en) * 2007-02-02 2008-08-14 Thomas Jefferson University Method and use of a bioreplaceable tissue material implant for treating snoring
US9492592B2 (en) 2007-02-28 2016-11-15 Orthopeutics, L. P. Crosslinker enhanced repair of knee meniscus
US9445936B2 (en) 2011-02-04 2016-09-20 Joseph E. Kovarik Method of treating snoring and obstructive sleep apnea
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: SCHREIBER, HANS, DR. DR., 69469 WEINHEIM, DE

8139 Disposal/non-payment of the annual fee