DE3918736C2 - Plastic coated metal mesh stents - Google Patents
Plastic coated metal mesh stentsInfo
- Publication number
- DE3918736C2 DE3918736C2 DE19893918736 DE3918736A DE3918736C2 DE 3918736 C2 DE3918736 C2 DE 3918736C2 DE 19893918736 DE19893918736 DE 19893918736 DE 3918736 A DE3918736 A DE 3918736A DE 3918736 C2 DE3918736 C2 DE 3918736C2
- Authority
- DE
- Germany
- Prior art keywords
- characterized
- metal
- stent
- coating
- metal mesh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
Description
Gegenstand der Erfindung sind kunststoffüberzogene Metallgitter stents zur permanenten Dehnung von arteriellen Verengungen. The invention relates to plastic-coated metal mesh stents for the permanent elongation of arterial narrowing.
Nach transluminaler Dehnung von arteriellen Stenosen mit einem Ballonkatheter oder nach Wiedereröffnung komplett verschlossener Gefäße kann in vielen Fällen das Lumen nicht bleibend offen gehalten werden, da sich Teile der Intima wie ein Ventil verschließend nach innen legen. After transluminal expansion of arterial stenosis with a balloon catheter or by re-opening completely blocked blood vessels, the lumen in many cases can not be kept permanently open, since parts of the intima lay like a valve occlusive inside.
Dies führt bei bestimmten Lokalisationen (z. B. der Koronar arterien) zu einer kritischen Situation, die eine notfallmäßige Bypass-Operation mit hohem Risiko für den Patienten erforderlich macht; This results in certain locations (. Eg coronary arteries) to a critical situation that requires an emergency even bypass surgery at high risk for the patient; in jedem Fall verhindert es jedoch den angestrebten Akuterfolg. but in any case it prevents the targeted acute success.
Seit einigen Jahren wird mit Gefäßendoprothesen, sogenannten Stents, experimentiert, die aus einem Geflecht von Metalldrähten (meist in Gitterform) bestehen und entweder als selbstexpan dierende (aktive) Stents (Sigwart, U., Puel, J. Mirkovitch, V., Joffre, F., Kappenberger, L.: "Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty", New Engl. J. Med. 316, 701 (1987) und Palmaz, JC, Richter, GM, Noeldge, G. et al: Intraluminal stents in atherosclerotic iliuc artery stenoses. Preliminary report of an multicenter study, Radiology 168 (1988), 727) oder mit dem Ballonkatheter an Ort und Stelle aufzudehnende (passive) Stents (Strecker, EP, Romaniuk, R., Schneider, B., Westphal, M., Zeitler, E., Wolf, HRD, Freudenberg, N.: Perkutan implantierbare, durch Ballon aufdehn bare Gefäßprothese DMW 113 (1988), 538) vorliegen und als innere Stütze das Gefäß offenhalten. For several years, experimented with vascular endoprostheses, so-called stents (usually in grid form) are made of a mesh of metal wires and either selbstexpan rocketing (active) stent (Sigwart, U., Puel, J. Mirkovitch, V., Joffre, .. F., Kappenberger, L .: "Intravascular stents to prevent restenosis and occlusion after transluminal angioplasty," New Engl J Med 316, 701 (1987) and Palmaz JC, judges, GM, Noeldge, G. et al: intraluminal stents in atherosclerotic iliuc artery stenoses. Preliminary report of an multicenter study, Radiology 168 (1988), 727) or with the balloon catheter in place aufzudehnende (passive) stents (Strecker, EP, Romaniuk, R., Schneider, B. , Westphal, M. Zeitler, E., Wolf, HRD, Freudenberg, N .: percutaneously implantable aufdehn by balloon bare vascular prosthesis DMW 113 (1988), there are 538) and as inner support hold open the vessel.
Obwohl diese Gefäßendoprothesen aus einem blut- und gewebever träglichen Material, z. Although these vascular endoprostheses from a blood and tissue sealing träglichen material, eg. B. vergoldetem Stahldraht, hergestellt werden, weisen sie jedoch eine nicht zu unterschätzende Thrombogenität auf, der, um Frühverschlüsse zu vermeiden, mit hohen (potentiell gefährlichen) Dosen von gerinnungshemmenden Medikamenten begegnet werden muß. However, for example, gold-plated steel wire are prepared, they have a not to be underestimated thrombogenicity, which, in order to prevent premature closures, with high (potentially hazardous) doses must be countered of anticoagulant drugs. Danach, dh in wenigen Wochen, werden die Metalldrähte durch die Gefäß-Innenhaut, das Endothel, überwachsen, so daß eine glatte, relativ athrombogene Oberfläche entsteht. Thereafter, ie within a few weeks, the metal wires are overgrown by the vessel inner skin, the endothelium so that a smooth, relatively athrombogeneous surface. Die Hoffnung, die Rate der Rezidive durch die Einlage solcher Gefäßendoprothesen senken zu können, hat sich jedoch bisher nicht bestätigen lassen (Mahler, F., Do, D., Triller, J., Thalmann, R., Walpoth, B.: Verlaufsergebnisse nach perkutaner Einlage arterieller Endoprothesen (stents) in die Beinarterien, VASA, Suppl. 23, 176-177 (1988). Das Problem scheint in der Durchwachsung des Gitters durch Gewebszellen zu sein. Deren Wachstum, welches durch das eingeführte Stent stimuliert wurde, hört nämlich nicht nach vollständiger Umkleidung des Geflechts auf, sondern geht weiter und kann dadurch zu einem erneuten vollständigen oder teilweisen Verschluß des Gefäßes führen. The hope of being able to reduce the rate of relapses by the deposit of such vascular endoprostheses, has come up so far not confirmed (Mahler, F., Do, D., trills, J., Thalmann, R., Walpoth, B .: History results after percutaneous insert arterial prostheses (stents) in the leg arteries, VASA, Suppl. 23, 176-177 (1988). the problem seems to be in the intergrowth of the grating by tissue cells. Their growth, which was stimulated by the inserted stent hears namely, not after complete casing of the braid, but rather goes on and can thereby lead to a complete or partial re-occlusion of the vessel.
Die EP 0 150 608 offenbart eine Ventilvorrichtung, insbesondere eine künstliche Herzklappe aus einem Grundkörper, welcher ebenfalls "Stent" genannt wird und blattförmigen Ventilklappen, wobei alle beweglichen Teile mit einem biokompatiblen Material aus einem synthetischen Polymer, welches unter anderem auch PTFE sein kann, überzogen sind. EP 0150608 discloses a valve device, particularly an artificial heart valve of a base body, is which is also called a "stent" and sheet-shaped valve flaps, wherein all the moving parts with a biocompatible material of a synthetic polymer, which may be, inter alia, PTFE, coated are. Dieser Überzug soll einerseits die Oberflächen glätten und andererseits den Reibungswiderstand und damit den Abrieb der äußeren Oberflächen verringern. This coating on the one hand smooth the surfaces and on the other hand reduce the frictional resistance and the abrasion of the outer surfaces. Auf die Problematik der Stimulation des Gewebswachstums geht dies Schrift nicht ein. On the issue of stimulation of tissue growth, it is not a font.
In der US 4 768 507 ist ein Stent aus einem Spiralfedermaterial und eine spezielle Vorrichtung, mit der eine solche Spiralfeder in ein vergleichsweise dünnes Gefäß eingebracht werden kann offenbart. In US 4,768,507 a stent made of a coil spring material, and a special device with which such a spiral spring can be introduced in a comparatively thin vessel is disclosed. Ein Problem dieser Spiralstents scheint eine Verletzung der Gefäßwand beim Einbetten in die Gefäße zu sein, welche einen Verschluß des Gefäßes innerhalb von 24 Stunden durch Blutablagerungen bewirkt Um diese Thrombose zu verhindern, wird die Spirale mit ULTI-Kohlenstoff (ultra low temperature isotropic carbon) umkleidet, wobei eine solche Umkleidung direkt auf das Federmaterial (Stahl oder Titanlegierungen) aufgebracht werden kann, oder nach vorheriger Beschichtung mit PTFE, welches als Primer wirken soll. One problem with this spiral stents appears to be an injury to the vessel wall when embedding into the vessels to be, which causes occlusion of the vessel within 24 hours by blood deposits To this thrombosis to prevent the spiral is clothed with ULTI carbon (ultra low temperature isotropic carbon) , such a casing may be applied directly on the spring material (steel or titanium alloys), or by prior coating with PTFE, which is to act as a primer. Das Problem eines Zuwachsens der Gefäße durch Zellbildungsstimulierung über längere Zeiträume wird auch in dieser Schrift nicht angesprochen. The problem of Zuwachsens of vessels by stimulating cell formation over extended periods is not addressed in this document.
Aufgabe der vorliegenden Erfindung war es daher, eine Gefäßendo prothese zu entwickeln, welche einerseits ein verengtes Gefäß dauerhaft aufweitet; It is an object of the present invention to develop a Gefäßendo prosthesis, on the one hand widening a narrowed vessel permanently; andererseits nicht thrombogen wirkt und eine Durchwachsung durch Gewebszellen verhindert. on the other hand does not affect thrombogenic and an intergrowth prevented by tissue cells.
Diese Aufgabe wird überraschenderweise gelöst, indem man ein an sich bekanntes Metallgitterstent innen (und eventuell außen) mit einem dünnen Überzug aus Polytetrafluorethylen (PTFE oder PTF) überkleidet. This object is surprisingly solved by the inside a per se known metal mesh stent (and possibly exterior) clothed with a thin coating of polytetrafluoroethylene (PTFE or PTF).
Polytetrafluorethylen, ein Polymerisat der Formel -(CF 2 -CF 2 ) n mit n = 5000-100 000 ist ein bekanntes Produkt, welches aufgrund seiner großen chemischen Beständigkeit in großem Umfang für vielfältige Beschichtungen und Auskleidungen im chemischen Apparatebau verwendet wird. Polytetrafluoroethylene, a polymer of the formula - (CF 2 -CF 2) n with n = 5000-100000 is a known product, which is used because of its high chemical resistance on a large scale for a variety of coatings and linings in chemical apparatus. Seit einiger Zeit findet dieses Material auch medizinische Anwendung zur Beschichtung von Gelenkprothesen. For some time, this material is also medical application for coating prosthetic joints. Seit längerem werden dünne Schläuche aus PTFE mit großem Erfolg auch als Gefäßprothesen (Bypässe) eingesetzt. Has long thin tubes made of PTFE with great success as vascular prostheses (grafts) are used. Eine spezielle mikroporöse Struktur sorgt für ein organisches Verwachsen der Enden mit den zu verbindenden Gefäßen. A special microporous structure provides for an organic coalescence of the ends to be joined vessels.
Erfindungsgemäß wird entweder eine Dispersion aus PTF um ein entsprechendes Stent aus Metallgitter herumgesintert oder eine sehr dünne, von einem Block aus PTF abgeschälte Folie von innen in das Stent eingelegt und unter Erwärmen bis zu 370-380°C und/oder unter Anwendung von Druck mit dem Stent verbunden. According to the invention either herumgesintert a dispersion of PTF to a corresponding stent of metal grid or a very thin, peeled by a block of PTF film from the inside inserted into the stent and with heating up to 370-380 ° C and / or under application of pressure with connected to the stent. Gegebenenfalls kann eine weitere Folie von außen um das Stent gelegt werden, um eine vollständige Einschließung des Metalls zu erreichen. Optionally, a further film from the outside can be placed around the stent to achieve a complete enclosure of the metal. Die Folie kann gegebenenfalls auch zu einem Schlauch vernäht werden. The film can also be sewn into a tube, if appropriate.
Auf diese Weise wird die Thrombogenität, die zu Frühverschlüssen führen kann und die Durchwachsbarkeit, die die Spätverschlüsse der Gefäßendoprothesen bewirkt, vermieden. In this way, the thrombogenicity, which can lead to early closures and Durchwachsbarkeit which causes the late closures of vascular endoprostheses avoided.
Da das Metall des Stents somit nicht mehr mit dem Blut und dem Gewebe in Berührung kommt, kann das Geflecht aus relativ preiswertem Stahldraht, vorzugsweise einem rostfreien Stahl, bestehen, wobei natürlich auch gewebeverträgliche Metalle genügender Härte wie Titan oder Edelmetalle eingesetzt werden können. Since the metal of the stent is thus no longer comes into contact with the blood and the tissue web of relatively inexpensive steel wire may, preferably a stainless steel, wherein, of course, also tissue-compatible metals sufficient hardness such as titanium or noble metals may be used.
Die erfindungsgemäßen Stents werden in üblicher Weise über einen in das Gefäß eingebrachten Katheter in die verengte Stelle eingebracht. The stents according to the invention are introduced in a conventional manner through a catheter introduced into the vessel in the restricted site. Damit der Stent dabei das Gefäß passieren kann, muß er vorher nach Möglichkeit um den Katheter komprimiert werden, um erst am Wirkort durch die eigene Spannkraft oder mit Hilfe eines Ballon-Katheters auf die benötigte Weite ausgedehnt zu werden. Thus, the stent can thereby pass through the vessel, it must be previously compressed as far as possible around the catheter to be extended only at the site of action by its own resilience or by using a balloon catheter to the required size.
Die vorgeformte endgültige Weite beginnt bei etwa 2 mm Durch messer, größere Durchmesser von z. The preformed final length starts at about 2 mm diameter larger diameters of z. B. 3-12 mm ermöglichen den Einsatz in anderen Gefäßgebieten (z. B. Bein-, Becken- oder Nierenarterien, Aorta, Halsschlagadern, Koronararterien usw.). B. 3-12 mm enable use in other vascular regions (z. B. leg, pelvic or renal arteries, aorta, carotid arteries, coronary arteries, etc.).
Während die bekannten, nur aus einem Metallgitter bestehenden Stents dehnbar sind und sich zusammendrücken oder durch Längsdehnung im Querschnitt verengen lassen, ist der erfindungs gemäße PTFE-Überzug nicht bzw. nur sehr wenig dehnbar. While the known, consisting only of a metal mesh stents are expandable and compress or constrict blank by longitudinal expansion in cross-section, the fiction, modern PTFE coating is not or only very slightly extensible. Die notwendige Querschnittsverringerung beim Einführen in das Gefäß wird daher vorzugsweise durch eine oder mehrere Längsfalten erreicht und der ursprüngliche Querschnitt durch Dehnung mit einem Ballon-Katheter erreicht, wobei die Falte ausgeklappt wird. The necessary cross-sectional reduction during insertion into the vessel is thus preferably accomplished by one or more longitudinal folds and the original cross-section achieved by expansion with a balloon catheter, where the fold is expanded. Alternativ kann bei einer schraubenförmigen Metalleinlage die Querschnittsverengung durch Verdrillen erzeugt werden. Alternatively, the cross-sectional constriction can be produced by twisting in a helical metal insert. Die Erfindung soll jedoch nicht auf diese Ausführungsformen beschränkt sein. However, the invention is not limited to these embodiments.
Die notwendige Flexibilität des Stents wird durch den PTFE-Über zug nicht beeinträchtigt; The flexibility of the stent is affected by the PTFE About not train; dies ist für den Einschub in Gefäß biegungen wichtig. this is for insertion into vessel bends important.
In den folgenden Figuren ist die Erfindung näher erläutert, ohne daß diese dadurch begrenzt sein soll. In the following figures, the invention is explained in more detail, without that this should be limited thereby.
Fig. 1 zeigt ein konventionelles Metallgitterstent. Fig. 1 shows a conventional metal mesh stent.
Fig. 2 zeigt ein Metallgitterstent mit PFTE-Innenauskleidung. Fig. 2 shows a metal mesh stent with PTFE liner.
Fig. 3 zeigt ein Metallgitterstent mit Innenauskleidung in komprimiertem Zustand. Fig. 3 shows a metal mesh stent having inner liner in the compressed state.
Fig. 4 zeigt ein Metallgitterstent mit Innen-und Außenbelag von PTFE. Fig. 4 shows a metal mesh stent having interior and exterior coating of PTFE.
Im einzelnen zeigt die Fig. 1 ein konventionelles Metallgitter stent, wobei aus dünnen Drähten, die beispielsweise aus Tantal oder einem Edelmetall bestehen können, ein Schlauch ( 1 ) gewirkt ist, dessen Drahtmaschen ( 2 ) zur Einführung in ein Gefäß komprimiert oder in die Länge gezogen werden können, so daß sich der Querschnitt des Stents verringert. In detail, the FIG. 1 shows a conventional metal mesh stent, being knitted from thin wires, which can consist, for example, tantalum or a noble metal, a hose (1), the wire mesh (2) is compressed or for introduction into a vessel in the length can be drawn so that the cross section of the stent is reduced. Nach Einbringen in das Gefäß kann das Stent dann auf den Gefäßdurchmesser wieder aufgeweitet werden. After introduction into the vessel, the stent may then be expanded to the vessel diameter again.
Die Fig. 2 zeigt ein entsprechendes Metallgitterstent ( 1 ) im Querschnitt, wobei die Metalldrahtmaschen ( 2 ) durch dicke und dünne Umfangslinien angedeutet sind. Fig. 2 shows a corresponding metal mesh stent (1) in cross-section, the metal wire mesh (2) are indicated by thick and thin circumferential lines. Das Stent ist innen mit einer PTFE-Schicht ( 3 ) ausgekleidet, wobei aus zeichentechnischen Gründen ein Abstand zu den Drahtmaschen ( 2 ) angedeutet ist, im Gebrauch liegen Schlauch und Maschen allerdings eng aneinander. The stent is lined with a PTFE-layer (3), from sign reasons, a distance from the wire mesh (2) is indicated, are in use, and hose mesh but close to each other.
In Fig. 3 ist ein entsprechender Stent ( 1 ) aus Tantaldraht ( 2 ) mit einer Innenauskleidung aus PTFE ( 3 ) in komprimiertem Zustand abgebildet, was dadurch angedeutet ist, daß die Metalldraht maschen sich fast berühren. In Fig. 3 a corresponding stent (1) made of tantalum wire (2) is shown with an inner lining of PTFE (3) in the compressed state, which is indicated by the fact that the metal wire meshes are almost touching. Der PTFE-Innenschlauch ist zum Ausgleich des verringerten Umfangs mit einer zusätzlichen Falte ( 4 ) abgebildet, welche sich beim Ausdehnen des Stents, wie in Fig. 2 dargestellt, glatt an das Metallgitter anliegt. The PTFE tube is ready to compensate for the reduced circumference with an additional fold (4) which is applied to upon expansion of the stent, as shown in Fig. 2, straight to the metal grid.
In Fig. 4 ist ein weiterer Metallgitterstent ( 1 ) mit einem Innenschlauch ( 3 ) und einem Außenmantel ( 5 ) wiedergegeben. In FIG. 4, a further metal mesh stent (1) with an inner tube (3) and an outer jacket (5) is reproduced. Je nach Herstellungsweise sind diese beiden PTFE-Hüllen zwischen den Drahtmaschen ( 2 ) miteinander verbunden. Depending on the production, both of these cases PTFE between the wire mesh (2) are connected together.
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19893918736 DE3918736C2 (en) | 1989-06-08 | 1989-06-08 | Plastic coated metal mesh stents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19893918736 DE3918736C2 (en) | 1989-06-08 | 1989-06-08 | Plastic coated metal mesh stents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3918736A1 DE3918736A1 (en) | 1990-12-13 |
DE3918736C2 true DE3918736C2 (en) | 1998-05-14 |
Family
ID=6382362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19893918736 Expired - Lifetime DE3918736C2 (en) | 1989-06-08 | 1989-06-08 | Plastic coated metal mesh stents |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE3918736C2 (en) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6352561B1 (en) | 1996-12-23 | 2002-03-05 | W. L. Gore & Associates | Implant deployment apparatus |
US6352553B1 (en) | 1995-12-14 | 2002-03-05 | Gore Enterprise Holdings, Inc. | Stent-graft deployment apparatus and method |
US6361637B2 (en) | 1995-12-14 | 2002-03-26 | Gore Enterprise Holdings, Inc. | Method of making a kink resistant stent-graft |
US6517570B1 (en) | 1994-08-31 | 2003-02-11 | Gore Enterprise Holdings, Inc. | Exterior supported self-expanding stent-graft |
US6551350B1 (en) | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
US6613072B2 (en) | 1994-09-08 | 2003-09-02 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
US6758858B2 (en) | 1995-03-10 | 2004-07-06 | Bard Peripheral Vascular, Inc. | Diametrically adaptable encapsulated stent and methods for deployment thereof |
US7927368B2 (en) | 2002-03-25 | 2011-04-19 | Kieran Murphy Llc | Device viewable under an imaging beam |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8157940B2 (en) | 1995-03-10 | 2012-04-17 | Bard Peripheral Vascular, Inc. | Methods for making a supported graft |
US8196279B2 (en) | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
US8206427B1 (en) | 1994-06-08 | 2012-06-26 | Medtonic Vascular, Inc. | Apparatus and methods for endoluminal graft placement |
US9375203B2 (en) | 2002-03-25 | 2016-06-28 | Kieran Murphy Llc | Biopsy needle |
US9427254B2 (en) | 2002-03-25 | 2016-08-30 | Kieran Murphy Llc | Apparatus for use in a surgical procedure |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4102550A1 (en) * | 1990-02-02 | 1991-08-08 | Stephan Prof Dr Bockenheimer | Sealing blood vessel fistula - involves inserted sleeve with spiral support with turns bridged by impervious elastic material |
ES2085435T3 (en) * | 1990-10-09 | 1996-06-01 | Cook Inc | Percutaneous dilator device. |
US5662713A (en) * | 1991-10-09 | 1997-09-02 | Boston Scientific Corporation | Medical stents for body lumens exhibiting peristaltic motion |
US5876445A (en) | 1991-10-09 | 1999-03-02 | Boston Scientific Corporation | Medical stents for body lumens exhibiting peristaltic motion |
US5683448A (en) | 1992-02-21 | 1997-11-04 | Boston Scientific Technology, Inc. | Intraluminal stent and graft |
FR2688401B1 (en) * | 1992-03-12 | 1998-02-27 | Thierry Richard | Expandable endoprosthesis for human or animal tubular member, and setting tool. |
JP2660101B2 (en) * | 1992-05-08 | 1997-10-08 | シュナイダー・(ユーエスエイ)・インコーポレーテッド | Esophageal stents and vehicles |
DE4222380A1 (en) | 1992-07-08 | 1994-01-13 | Ernst Peter Prof Dr M Strecker | In the body of a patient percutaneously implantable endoprosthesis |
US5707376A (en) * | 1992-08-06 | 1998-01-13 | William Cook Europe A/S | Stent introducer and method of use |
US6336938B1 (en) | 1992-08-06 | 2002-01-08 | William Cook Europe A/S | Implantable self expanding prosthetic device |
DK0653924T3 (en) * | 1992-08-06 | 1997-07-14 | Cook William Europ | prosthetic device for sustaining the lumen of a vessel or a hollow organ. |
CA2146156C (en) * | 1992-10-13 | 2004-11-30 | Erik Andersen | Medical stents for body lumens exhibiting peristaltic motion |
BE1006440A3 (en) * | 1992-12-21 | 1994-08-30 | Dereume Jean Pierre Georges Em | Luminal endoprosthesis AND METHOD OF PREPARATION. |
JP3583801B2 (en) * | 1993-03-03 | 2004-11-04 | ボストン サイエンティフィック リミテッドBoston Scientific Limited | Stent and graft of the luminal cavity |
ES2114964T3 (en) | 1993-04-23 | 1998-06-16 | Schneider Europ Ag | Endoprosthesis with a coating of elastic material and method for applying the layer on the endoprosthesis. |
CA2158757C (en) * | 1993-04-23 | 2000-01-04 | Joseph E. Laptewicz Jr. | Covered stent and stent delivery device |
DE69431302D1 (en) * | 1993-08-18 | 2002-10-10 | Gore & Ass | Rohrfoermiges intraluminal usable tissue |
US6027779A (en) * | 1993-08-18 | 2000-02-22 | W. L. Gore & Associates, Inc. | Thin-wall polytetrafluoroethylene tube |
US6159565A (en) * | 1993-08-18 | 2000-12-12 | W. L. Gore & Associates, Inc. | Thin-wall intraluminal graft |
US5735892A (en) | 1993-08-18 | 1998-04-07 | W. L. Gore & Associates, Inc. | Intraluminal stent graft |
US6025044A (en) | 1993-08-18 | 2000-02-15 | W. L. Gore & Associates, Inc. | Thin-wall polytetrafluoroethylene tube |
US5723004A (en) | 1993-10-21 | 1998-03-03 | Corvita Corporation | Expandable supportive endoluminal grafts |
US5632772A (en) * | 1993-10-21 | 1997-05-27 | Corvita Corporation | Expandable supportive branched endoluminal grafts |
US5639278A (en) * | 1993-10-21 | 1997-06-17 | Corvita Corporation | Expandable supportive bifurcated endoluminal grafts |
US5855598A (en) * | 1993-10-21 | 1999-01-05 | Corvita Corporation | Expandable supportive branched endoluminal grafts |
US6051020A (en) | 1994-02-09 | 2000-04-18 | Boston Scientific Technology, Inc. | Bifurcated endoluminal prosthesis |
US5609627A (en) | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US5584876A (en) * | 1994-04-29 | 1996-12-17 | W. L. Gore & Associates, Inc. | Cell excluding sheath for vascular grafts |
DE69532636D1 (en) | 1994-05-06 | 2004-04-08 | Impra Inc | An apparatus for treating a body vessel |
DE69530891T2 (en) * | 1994-06-27 | 2004-05-13 | Corvita Corp., Miami | Bistable luminal graft endoprosthesis |
WO1996000103A1 (en) | 1994-06-27 | 1996-01-04 | Endomed, Inc. | Radially expandable polytetrafluoroethylene and expandable endovascular stents formed therewith |
US5522881A (en) * | 1994-06-28 | 1996-06-04 | Meadox Medicals, Inc. | Implantable tubular prosthesis having integral cuffs |
DE4424242A1 (en) * | 1994-07-09 | 1996-01-11 | Ernst Peter Prof Dr M Strecker | In the body of a patient percutaneously implantable endoprosthesis |
JPH0847540A (en) * | 1994-08-09 | 1996-02-20 | Olympus Optical Co Ltd | Stent for indwelling in vascular cavity and its production |
US6124523A (en) * | 1995-03-10 | 2000-09-26 | Impra, Inc. | Encapsulated stent |
ES2151082T3 (en) * | 1995-03-10 | 2000-12-16 | Impra Inc | Encapsulated endoluminal support and processes for their manufacture and endoluminal. |
DE69533289D1 (en) | 1995-08-24 | 2004-08-26 | Bard Peripheral Vascular Inc | The assembling method of an enveloped, endoluminal stent |
DK171865B1 (en) * | 1995-09-11 | 1997-07-21 | Cook William Europ | An expandable endovascular stent |
US5788626A (en) | 1995-11-21 | 1998-08-04 | Schneider (Usa) Inc | Method of making a stent-graft covered with expanded polytetrafluoroethylene |
AT218052T (en) | 1995-11-27 | 2002-06-15 | Schneider Europ Gmbh | Stent for application in a bodily passage |
DK0886501T3 (en) * | 1996-03-07 | 2003-11-24 | Med Inst Inc | An expandable stent |
US5928279A (en) * | 1996-07-03 | 1999-07-27 | Baxter International Inc. | Stented, radially expandable, tubular PTFE grafts |
US6315791B1 (en) | 1996-12-03 | 2001-11-13 | Atrium Medical Corporation | Self-expanding prothesis |
US6010529A (en) | 1996-12-03 | 2000-01-04 | Atrium Medical Corporation | Expandable shielded vessel support |
US5925074A (en) * | 1996-12-03 | 1999-07-20 | Atrium Medical Corporation | Vascular endoprosthesis and method |
US6039755A (en) * | 1997-02-05 | 2000-03-21 | Impra, Inc., A Division Of C.R. Bard, Inc. | Radially expandable tubular polytetrafluoroethylene grafts and method of making same |
DE19723723C2 (en) * | 1997-05-30 | 1999-05-20 | Fraunhofer Ges Forschung | Polymer coating for prostheses, implants and body electrodes and methods for their preparation |
US20030171804A1 (en) * | 1997-06-24 | 2003-09-11 | Werner Krause | Stents coated with fluoroalkyl groups |
US6398803B1 (en) | 1999-02-02 | 2002-06-04 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Partial encapsulation of stents |
DE20014019U1 (en) * | 2000-08-16 | 2002-01-03 | Allstent Ag | stent |
CA2981561A1 (en) | 2001-10-04 | 2003-04-10 | Neovasc Medical Ltd. | Flow reducing implant |
US6814561B2 (en) | 2001-10-30 | 2004-11-09 | Scimed Life Systems, Inc. | Apparatus and method for extrusion of thin-walled tubes |
US7597775B2 (en) | 2001-10-30 | 2009-10-06 | Boston Scientific Scimed, Inc. | Green fluoropolymer tube and endovascular prosthesis formed using same |
US8187318B2 (en) | 2005-08-31 | 2012-05-29 | Advanced Bio Prosthetic Surfaces, Ltd. | Covered stent with proximal and distal attachment, delivery catheter, and method of making same |
US8087923B1 (en) | 2007-05-18 | 2012-01-03 | C. R. Bard, Inc. | Extremely thin-walled ePTFE |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0150608A1 (en) * | 1983-12-28 | 1985-08-07 | Shiley Inc. | Stent covering for tissue valves |
US4768507A (en) * | 1986-02-24 | 1988-09-06 | Medinnovations, Inc. | Intravascular stent and percutaneous insertion catheter system for the dilation of an arterial stenosis and the prevention of arterial restenosis |
-
1989
- 1989-06-08 DE DE19893918736 patent/DE3918736C2/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0150608A1 (en) * | 1983-12-28 | 1985-08-07 | Shiley Inc. | Stent covering for tissue valves |
US4768507A (en) * | 1986-02-24 | 1988-09-06 | Medinnovations, Inc. | Intravascular stent and percutaneous insertion catheter system for the dilation of an arterial stenosis and the prevention of arterial restenosis |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8206427B1 (en) | 1994-06-08 | 2012-06-26 | Medtonic Vascular, Inc. | Apparatus and methods for endoluminal graft placement |
US6517570B1 (en) | 1994-08-31 | 2003-02-11 | Gore Enterprise Holdings, Inc. | Exterior supported self-expanding stent-graft |
US6613072B2 (en) | 1994-09-08 | 2003-09-02 | Gore Enterprise Holdings, Inc. | Procedures for introducing stents and stent-grafts |
US8097642B2 (en) | 1995-02-15 | 2012-01-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8158670B2 (en) | 1995-02-15 | 2012-04-17 | Boston Scientific Scimed, Inc. | Therapeutic inhibitor of vascular smooth muscle cells |
US8157940B2 (en) | 1995-03-10 | 2012-04-17 | Bard Peripheral Vascular, Inc. | Methods for making a supported graft |
US6758858B2 (en) | 1995-03-10 | 2004-07-06 | Bard Peripheral Vascular, Inc. | Diametrically adaptable encapsulated stent and methods for deployment thereof |
US6797217B2 (en) | 1995-03-10 | 2004-09-28 | Bard Peripheral Vascular, Inc. | Methods for making encapsulated stent-grafts |
US7939000B2 (en) | 1995-03-10 | 2011-05-10 | Bard Peripheral Vascular, Inc. | Methods for making an encapsulated stent and intraluminal delivery thereof |
US6352553B1 (en) | 1995-12-14 | 2002-03-05 | Gore Enterprise Holdings, Inc. | Stent-graft deployment apparatus and method |
US6361637B2 (en) | 1995-12-14 | 2002-03-26 | Gore Enterprise Holdings, Inc. | Method of making a kink resistant stent-graft |
US6520986B2 (en) | 1995-12-14 | 2003-02-18 | Gore Enterprise Holdings, Inc. | Kink resistant stent-graft |
US6551350B1 (en) | 1996-12-23 | 2003-04-22 | Gore Enterprise Holdings, Inc. | Kink resistant bifurcated prosthesis |
US6352561B1 (en) | 1996-12-23 | 2002-03-05 | W. L. Gore & Associates | Implant deployment apparatus |
US7927368B2 (en) | 2002-03-25 | 2011-04-19 | Kieran Murphy Llc | Device viewable under an imaging beam |
US8465539B2 (en) | 2002-03-25 | 2013-06-18 | Kieran Murphy, Llc | Device viewable under an imaging beam |
US9028543B2 (en) | 2002-03-25 | 2015-05-12 | Kieran Murphy, Llc | Device viewable under an imaging beam |
US9375203B2 (en) | 2002-03-25 | 2016-06-28 | Kieran Murphy Llc | Biopsy needle |
US9427254B2 (en) | 2002-03-25 | 2016-08-30 | Kieran Murphy Llc | Apparatus for use in a surgical procedure |
US8196279B2 (en) | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
Also Published As
Publication number | Publication date |
---|---|
DE3918736A1 (en) | 1990-12-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Maass et al. | Radiological follow-up of transluminally inserted vascular endoprostheses: an experimental study using expanding spirals. | |
US9649209B2 (en) | Hybrid stent and method of making | |
US5824034A (en) | Method for repositioning a radially self-expanding implantable intraluminal device | |
KR0147482B1 (en) | Clad composite stent | |
US5653727A (en) | Intravascular stent | |
US6290721B1 (en) | Tubular medical endoprostheses | |
EP0707462B1 (en) | Internal graft prosthesis and delivery system | |
EP0824902B1 (en) | Expandable stent | |
ES2290302T3 (en) | Placement device for a self-expansible stent. | |
AU710134B2 (en) | Expandable supportive bifurcated endoluminal grafts | |
US5868780A (en) | Stents for supporting lumens in living tissue | |
US5824045A (en) | Vascular and endoluminal stents | |
US5195984A (en) | Expandable intraluminal graft | |
JP2933226B2 (en) | Apparatus for stretching the extensible intraluminal vascular graft and a body passageway lumen | |
DE19547617C1 (en) | Appliance for inserting and replacing surgical implant | |
JP4864889B2 (en) | Delivery device with reduced force to deploy | |
US5935161A (en) | Non-migrating vascular prosthesis and minimally invasive placement system therefor | |
KR100386784B1 (en) | Expansive branch stent and its implantation method | |
US7854760B2 (en) | Medical devices including metallic films | |
DE69735530T2 (en) | Flat wire stent | |
EP0417928B1 (en) | Endovascular support device and method | |
US4740207A (en) | Intralumenal graft | |
US5632772A (en) | Expandable supportive branched endoluminal grafts | |
AU649051B2 (en) | Endovascular grafting apparatus, system and method and devices for use therewith | |
DE60225932T2 (en) | System for fixing endoluminal devices |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
8125 | Change of the main classification |
Ipc: A61L 27/00 |
|
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8380 | Miscellaneous part iii |
Free format text: IN DER PATENTSCHRIFT WURDEN DIE ZEICHNUNGEN UNVOLLSTAENDIG VEROEFFENTLICHT. ES FOLGT ERGAENZUNGSDRUCK DER FEHLENDEN FIGUREN 2-4 |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: ATRIUM MEDICAL CORP., HUDSON, N.H., US |
|
8381 | Inventor (new situation) |
Free format text: VALLBRACHT, CHRISTIAN, DR., 36199 ROTENBURG, DE |