DE3852918T2 - Pig TGEV virus as a vaccine for dogs. - Google Patents

Pig TGEV virus as a vaccine for dogs.

Info

Publication number
DE3852918T2
DE3852918T2 DE3852918T DE3852918T DE3852918T2 DE 3852918 T2 DE3852918 T2 DE 3852918T2 DE 3852918 T DE3852918 T DE 3852918T DE 3852918 T DE3852918 T DE 3852918T DE 3852918 T2 DE3852918 T2 DE 3852918T2
Authority
DE
Germany
Prior art keywords
vaccine
dogs
tgev virus
pig
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3852918T
Other languages
German (de)
Other versions
DE3852918D1 (en
Inventor
Dale Bordt
Hans Beecham Inc Draayer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Beecham Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Inc filed Critical Beecham Inc
Application granted granted Critical
Publication of DE3852918D1 publication Critical patent/DE3852918D1/en
Publication of DE3852918T2 publication Critical patent/DE3852918T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A61K39/225—Porcine transmissible gastroenteritis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/265—Infectious rhinotracheitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20061—Methods of inactivation or attenuation
    • C12N2770/20063—Methods of inactivation or attenuation by chemical treatment

Abstract

Sterile pharmaceutical compositions for use in therapy especially inactivated vaccines for use in prophylaxis, are prepared by inactivating a live virus or bacterium with ascorbic acid and/or a salt thereof in the presence of oxygen and a source of heavy metal ions. Methods of treating animals, including humans, with such compositions are also disclosed.
DE3852918T 1987-09-28 1988-09-26 Pig TGEV virus as a vaccine for dogs. Expired - Fee Related DE3852918T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10182287A 1987-09-28 1987-09-28

Publications (2)

Publication Number Publication Date
DE3852918D1 DE3852918D1 (en) 1995-03-16
DE3852918T2 true DE3852918T2 (en) 1995-07-13

Family

ID=22286587

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3852918T Expired - Fee Related DE3852918T2 (en) 1987-09-28 1988-09-26 Pig TGEV virus as a vaccine for dogs.
DE88308908T Expired - Fee Related DE3886332T2 (en) 1987-09-28 1988-09-26 Inactivating viruses and bacteria.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE88308908T Expired - Fee Related DE3886332T2 (en) 1987-09-28 1988-09-26 Inactivating viruses and bacteria.

Country Status (14)

Country Link
EP (2) EP0310316B1 (en)
JP (2) JP2715114B2 (en)
KR (2) KR0135426B1 (en)
AT (2) ATE98680T1 (en)
AU (2) AU624081B2 (en)
CA (2) CA1332919C (en)
DE (2) DE3852918T2 (en)
DK (2) DK175308B1 (en)
ES (2) ES2067474T3 (en)
GR (1) GR3015608T3 (en)
IE (2) IE60950B1 (en)
NZ (2) NZ226333A (en)
PT (2) PT88590B (en)
ZA (2) ZA887195B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2067474T3 (en) * 1987-09-28 1995-04-01 Beecham Inc PORK TGEV VIRUSES AS A VACCINE FOR DOGS.
ES2076378T5 (en) * 1989-09-25 1999-10-16 Genetics Inst METHOD FOR THE INHIBITION OF THE DEVELOPMENT OF STEM CELLS.
US5276142A (en) * 1989-12-11 1994-01-04 American Cyanamid Company Process for purification of a 69000 dalton antigenic protein from Bordetella pertussis
ES2084057T3 (en) * 1990-06-07 1996-05-01 Bayer Ag BACTERINE FOR THE TREATMENT OF DISEASES CAUSED BY F. NECROPHORUM AND PROCEDURE FOR ITS PRODUCTION.
US6057436A (en) * 1990-11-14 2000-05-02 Pfizer Inc. Canine coronavirus S gene and uses therefor
US6372224B1 (en) 1990-11-14 2002-04-16 Pfizer Inc. Canine coronavirus S gene and uses therefor
JPH0813753B2 (en) * 1992-05-22 1996-02-14 株式会社微生物化学研究所 Bovine infectious rhinotracheitis virus infection, bovine viral diarrhea-mucosal disease virus infection, parainfluenza type 3 virus infection, bovine RS virus infection and bovine adenovirus 7 virus infection mixed vaccine
CA2146321A1 (en) * 1992-10-05 1994-04-14 Cassius M. Tucker High potency vaccines
JP2521226B2 (en) * 1993-01-28 1996-08-07 株式会社微生物化学研究所 Mixed vaccine for dogs
US5750112A (en) * 1993-02-26 1998-05-12 Solvay Animal Health, Inc. Canine coronavirus vaccine from feline enteric coronavirus
EP0612532A3 (en) * 1993-02-26 1998-02-04 Solvay Animal Health, Inc. Canine coronavirus vaccine from feline enteric coronavirus
US5362442A (en) 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
CN1103603C (en) * 1993-08-06 2003-03-26 康诺特实验室有限公司 Vaccin respiratory syncytial viral vaccines
CA2184132C (en) * 1995-09-21 2011-03-15 Kristina J. Hennessy An adjuvanted vaccine which is substantially free of non-host albumin
US6682746B2 (en) 1995-09-21 2004-01-27 Kristina J. Hennessy Adjuvanted vaccine which is substantially free of non-host albumin
US5853715A (en) * 1996-08-16 1998-12-29 Bayer Corporation Cross-protective equine herpesvirus preparations and method of making and using the same
UA78180C2 (en) * 1997-10-03 2007-03-15 Меріаль Porcine circovirus, vaccines and diagnostic reagents
EP0978286A1 (en) * 1998-08-07 2000-02-09 Bayer Corporation Cross-protective equine herpesvirus preparations and method of making and using the same
US6682695B2 (en) 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US7252799B2 (en) 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US20030095890A1 (en) 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US6908591B2 (en) 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
CN103709248B (en) * 2013-12-24 2019-07-16 北京大北农科技集团股份有限公司动物医学研究中心 A kind of anti-swine infectious enterogastritis virus hyper-immune serum and preparation method thereof
DE202020001666U1 (en) 2020-04-21 2020-06-08 Walther Enßlin Impregnation of the surface of clothing, protective clothing, tissue gloves against viruses from the droplets in the air we breathe
DE202020003865U1 (en) 2020-09-11 2021-09-22 Karin Emde Trapping and destruction of viruses and other microorganisms in room air and room air filters
DE102021001635A1 (en) 2021-03-27 2022-09-29 Karin Emde Trapping and destroying viruses and other microorganisms on surfaces, in room air, in the exhaust air from vacuum cleaners and in room air filters.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145144A (en) * 1951-08-09 1964-08-18 Takeda Pharmacentical Ind Ltd Process for manufacturing chromium treated vaccines
FR1488212A (en) * 1964-06-22 1967-07-13 Behringwerke Ag Method for reducing the foot-and-mouth disease virus
DE1253412B (en) * 1964-09-22 1967-11-02 Diamond Lab Inc Process for obtaining a vaccine against infectious swine gastroenteritis
US3925544A (en) * 1971-07-12 1975-12-09 Univ Southern Illinois Bovine vaccines and methods of making and using same
US3907986A (en) * 1972-12-18 1975-09-23 Rit Rech Ind Therapeut Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof
JPS5531762B2 (en) * 1973-03-28 1980-08-20
EP0000677B1 (en) * 1977-07-22 1981-08-05 Merck & Co. Inc. Parainfluenza virus vaccine and its preparation
JPS55104215A (en) * 1979-02-06 1980-08-09 Merck & Co Inc Parainfluenza virus vaccine and its manufacture
GB8502399D0 (en) * 1985-01-31 1985-03-06 Akzo Nv Canine parvovirus vaccines
ES2067474T3 (en) * 1987-09-28 1995-04-01 Beecham Inc PORK TGEV VIRUSES AS A VACCINE FOR DOGS.

Also Published As

Publication number Publication date
EP0310316A3 (en) 1990-02-14
CA1332919C (en) 1994-11-08
EP0310317A3 (en) 1990-02-14
ES2067474T3 (en) 1995-04-01
KR0135426B1 (en) 1998-04-23
EP0310316A2 (en) 1989-04-05
DK175308B1 (en) 2004-08-16
ATE117899T1 (en) 1995-02-15
JP2733844B2 (en) 1998-03-30
GR3015608T3 (en) 1995-06-30
IE66015B1 (en) 1995-11-29
ES2061673T3 (en) 1994-12-16
EP0310316B1 (en) 1995-02-01
KR890004725A (en) 1989-05-09
DK534288A (en) 1989-03-29
IE882908L (en) 1989-03-28
ZA887195B (en) 1989-07-26
DK175379B1 (en) 2004-09-20
PT88591B (en) 1992-11-30
PT88590B (en) 1993-04-30
PT88590A (en) 1988-10-01
DK534188A (en) 1989-03-29
NZ226333A (en) 1991-09-25
DE3886332D1 (en) 1994-01-27
AU624339B2 (en) 1992-06-11
CA1331562C (en) 1994-08-23
IE60950B1 (en) 1994-09-07
ZA887196B (en) 1989-07-26
AU2284388A (en) 1989-04-06
JP2715114B2 (en) 1998-02-18
DK534188D0 (en) 1988-09-26
AU624081B2 (en) 1992-06-04
IE882909L (en) 1989-03-28
DE3852918D1 (en) 1995-03-16
NZ226332A (en) 1991-10-25
JPH01230532A (en) 1989-09-14
AU2281488A (en) 1989-04-06
JPH01230523A (en) 1989-09-14
EP0310317B1 (en) 1993-12-15
DK534288D0 (en) 1988-09-26
ATE98680T1 (en) 1994-01-15
PT88591A (en) 1988-10-01
EP0310317A2 (en) 1989-04-05
DE3886332T2 (en) 1994-03-31
KR890004728A (en) 1989-05-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER INC. (N.D.GES.D. STAATES DELAWARE), NEW YOR

8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee