DE3850196D1 - Modified splenopentins, process for their preparation and their use. - Google Patents
Modified splenopentins, process for their preparation and their use.Info
- Publication number
- DE3850196D1 DE3850196D1 DE3850196T DE3850196T DE3850196D1 DE 3850196 D1 DE3850196 D1 DE 3850196D1 DE 3850196 T DE3850196 T DE 3850196T DE 3850196 T DE3850196 T DE 3850196T DE 3850196 D1 DE3850196 D1 DE 3850196D1
- Authority
- DE
- Germany
- Prior art keywords
- splenopentins
- modified
- preparation
- compounds
- splenopentines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/66—Thymopoietins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The compounds have the formula I <IMAGE> are prepared by acylation of splenopentines and are used as pharmacologically active peptides. The compounds are suitable for the normalisation of the function of the immune system in cases of primary and secondary immunodeficiency.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DD30397587A DD263778A1 (en) | 1987-06-19 | 1987-06-19 | PROCESS FOR THE PRODUCTION OF ACYLATED SPLENOPENTINES |
DD31108087A DD281089A7 (en) | 1987-12-23 | 1987-12-23 | PROCESS FOR THE CHROMATOGRAPHIC CLEANING OF ACYLATED SPLENOPENTIN PEPTIDES |
DD31214488A DD268160A1 (en) | 1988-01-08 | 1988-01-08 | METHOD FOR PRODUCING A MEDIUM ACTING ON BONE MARROW STAMPS |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3850196D1 true DE3850196D1 (en) | 1994-07-21 |
Family
ID=27179904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3850196T Expired - Fee Related DE3850196D1 (en) | 1987-06-19 | 1988-06-20 | Modified splenopentins, process for their preparation and their use. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0307553B1 (en) |
JP (1) | JPS6485998A (en) |
AT (1) | ATE107311T1 (en) |
DE (1) | DE3850196D1 (en) |
ES (1) | ES2056858T3 (en) |
HU (1) | HU199878B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD296084A5 (en) * | 1989-07-27 | 1991-11-21 | Adw | PROCESS FOR THE MANUFACTURE OF HUMAN SPLENINE DERIVATIVES |
DD292382B5 (en) * | 1990-03-06 | 1994-03-24 | Berlin Chemie Ag | METHOD FOR PRODUCING A PARENTERALLICALLY APPLICABLE STORAGE-RESISTANT IMMUNOSTIMULATING PREPARATION |
DE4011207A1 (en) * | 1990-04-06 | 1991-10-10 | Stiefel Thomas | HUMANE SPLENOPENTINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF |
EP0517126A1 (en) * | 1991-05-31 | 1992-12-09 | WOGEPHARM GmbH | Use of diacetyl-splenopentin in chemotherapy and radiation therapy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2938420A1 (en) * | 1979-09-22 | 1981-04-09 | Hoechst Ag, 6000 Frankfurt | NEW PEPTIDES AND METHOD FOR THEIR PRODUCTION |
US4309340A (en) * | 1980-03-31 | 1982-01-05 | American Home Products Corporation | Polypeptide compositions |
US4298523A (en) * | 1980-06-17 | 1981-11-03 | Ortho Pharmaceutical Corporation | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R |
HU185263B (en) * | 1981-06-12 | 1984-12-28 | Richter Gedeon Vegyeszet | Process for producing peptides effective on the immuncontroll analogous with the tp5 |
DE3401545A1 (en) * | 1983-08-03 | 1985-02-14 | Hoechst Ag, 6230 Frankfurt | NEW PEPTIDES WITH IMMUNE-STIMULATING EFFECT, METHOD FOR THE PRODUCTION AND THEIR USE |
US4629723A (en) * | 1984-06-27 | 1986-12-16 | Ortho Pharmaceutical Corporation | Potent thymopentin analogs |
-
1988
- 1988-06-16 HU HU883100A patent/HU199878B/en not_active IP Right Cessation
- 1988-06-20 AT AT88109774T patent/ATE107311T1/en not_active IP Right Cessation
- 1988-06-20 EP EP88109774A patent/EP0307553B1/en not_active Expired - Lifetime
- 1988-06-20 ES ES88109774T patent/ES2056858T3/en not_active Expired - Lifetime
- 1988-06-20 JP JP63150377A patent/JPS6485998A/en active Pending
- 1988-06-20 DE DE3850196T patent/DE3850196D1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0307553A3 (en) | 1990-05-09 |
EP0307553A2 (en) | 1989-03-22 |
JPS6485998A (en) | 1989-03-30 |
HU199878B (en) | 1990-03-28 |
ATE107311T1 (en) | 1994-07-15 |
HUT47310A (en) | 1989-02-28 |
EP0307553B1 (en) | 1994-06-15 |
ES2056858T3 (en) | 1994-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |